Gene Information

Name : Mycch_2798 (Mycch_2798)
Accession : YP_006453238.1
Strain : Mycobacterium chubuense NBB4
Genome accession: NC_018027
Putative virulence/resistance : Virulence
Product : urease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2922524 - 2924245 bp
Length : 1722 bp
Strand : +
Note : PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit

DNA sequence :
ATGAGCGCACTCTCCCGGCCGCGGTATGCCGCGCTGTACGGTCCCACCACCGGCGACCGCATCCGGCTCGCCGACACCGA
CCTTTTCGTCGAGATCACCGAAGATCGCAGCGGCGGGCCGGGGCTGGCCGGTGACGAGGCGGTGTTCGGCGGCGGCAAGG
TGCTGCGCGAGTCGATGGGTCAGTCGCGGGCCACCCGCGCCGACGGCGCCCCCGACACCGTGATCACCGGCGCGGTGATA
CTCGACTACTGGGGAATCATCAAGGCCGACATCGGGATTCGTGATGGGCGCGTCACCGCGATCGGCAAGGCGGGCAACCC
CGACATCATGTCGGGTGTGCACCCCGGCCTGGTGGTCGGCCCGTCGACGGAGATCATCGCCGGAAATGGGCGCATCCTCA
CCGCGGGCGCCATCGACTGCCACGTCCACCTGATCTGCCCGCAGATCATGGAGGAGGCGCTCGGCGGCGGCATCACCACG
ATCGTCGCCGGAGGCACGGGCCCCGCCGAAGGCAGCAAGGCCACCACCGTCACGCCGGGCGCGTGGCATCTGGCCCGCAT
GCTCGAAGCGCTCGACGGGTGGCCGCTCAACATCGCCCTCCTGGGCAAGGGGAACACCGTCAGCGCCGAGGCGATGTGGG
AGCAATTGCGCGGCGGCGCAGCCGGTTTCAAGCTGCACGAGGACTGGGGCACCACCCCGGCCGCCATCGACGCGTGCCTG
AGTGTGGCCGACGCGGCGGGCGTGCAGGTCAACATCCACACCGACACGCTCAACGAGGCGGGCTTCGTCGAGAACACCCT
CGCCGCGGTCAGGGGCCGGTCCATCCACGCCTACCACACCGAAGGCGCCGGCGGCGGCCACGCACCCGACATCATCACCG
TCGTCGGAGCGCCCAACGTGCTGCCCAGTTCCACGAATCCGACCCGGCCGCACACCGTCAACACACTCGACGAGCACCTC
GACATGCTGATGGTCTGCCATCACCTCAACCCCGCCGTCCCCGAGGATCTCGCGTTCGCCGAGAGCAGGATCCGGCCGTC
GACCATCGCTGCGGAGGACCTGCTGCACGACATCGGCGCGATCTCGATGATCGGCAGTGACGCGCAGGCGATGGGGCGCA
TCGGCGAGGTGGTGATGCGGACCTGGCAGACGGCGCATGTGATGAAGCGGCGCCGCGGGTTCCTGCCGGGGGACACGGCC
GCTGACAACACCCGCGCTCAGCGATACGTCGCCAAATACACGATCTGCCCGGCCGTCGCCCACGGACTCGACCGGGAGAT
CGGCTCCGTGGAGGTCGGCAAGCTGGCCGATCTGGTGCTGTGGGAGCCGGCGTTCTTCGGGGTGCGCCCGCACGCGGTGC
TCAAGGGCGGCATGATCGCGTGGGCGGCGATGGGGGATGCGAACGCCTCGATCCCCACACCGCAGCCGGTGCTGCCGCGA
CCGATGTTCGGTGCCGCGCCGGCGGCGGCCGCCGCGACGTCGGTGCACTTCGTCGCACCCCAGGCGATCGACGACGGGCT
GGCCGATCGGATCGCGGTGCGCCGGCGGCTCGTCGCGGTCGAGGACGTCCGCGCGATCGGCAAGGCGCAGATGCCGCTCA
ACGACGCGACTCCCGACATCGAGGTGGACCCGGACACGTTCACCGTGCGGATCGACGGCCAGGTGTGGCAGGAGCAGCCC
GCGGCCGAACTGCCGATGGCCCAGAGGTACTTCCTGTTCTGA

Protein sequence :
MSALSRPRYAALYGPTTGDRIRLADTDLFVEITEDRSGGPGLAGDEAVFGGGKVLRESMGQSRATRADGAPDTVITGAVI
LDYWGIIKADIGIRDGRVTAIGKAGNPDIMSGVHPGLVVGPSTEIIAGNGRILTAGAIDCHVHLICPQIMEEALGGGITT
IVAGGTGPAEGSKATTVTPGAWHLARMLEALDGWPLNIALLGKGNTVSAEAMWEQLRGGAAGFKLHEDWGTTPAAIDACL
SVADAAGVQVNIHTDTLNEAGFVENTLAAVRGRSIHAYHTEGAGGGHAPDIITVVGAPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPAVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKRRRGFLPGDTA
ADNTRAQRYVAKYTICPAVAHGLDREIGSVEVGKLADLVLWEPAFFGVRPHAVLKGGMIAWAAMGDANASIPTPQPVLPR
PMFGAAPAAAAATSVHFVAPQAIDDGLADRIAVRRRLVAVEDVRAIGKAQMPLNDATPDIEVDPDTFTVRIDGQVWQEQP
AAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-158 60
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-158 60
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-157 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycch_2798 YP_006453238.1 urease VFG0270 Protein 2e-139 53