Gene Information

Name : Mycch_2596 (Mycch_2596)
Accession : YP_006453047.1
Strain : Mycobacterium chubuense NBB4
Genome accession: NC_018027
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase (class II)
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 2685747 - 2689055 bp
Length : 3309 bp
Strand : -
Note : PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial

DNA sequence :
ATGACCTCCACGAGCGGGATGAGGACGCGCCCGGCCTCCAGTTACCGGTGGGTGCCCGCCGCGGCGGGATGGATCGTGGG
CGTCATCGCGACGCTGTCGCTGATGGCCAGCATCTCCCCGCTGATCCGGTGGCTGATCAAGGTCCCGCGCGAATTCGTCG
ACCACTACATCTTCAACTTTCCCGACACCAGCTTCGCCTGGGCGTTCGTCCTCGCGCTGCTGGCCGCCGCGTTGGCGGCG
CGCAAACGCATCGCCTGGTGGATCCTCGTGCTCTACATGGTCGGGTCGATCGGGTGGAACATTGTCGACATCGCGGGCCG
CGGCGAGACCTGGATGCGCGAATCCGGCGAGATGATCGGCCTCGCCTTCCACATCGCCTCGGTCGTCTTCCTCGTGCTGG
CCCGCAAGGAGTTCTGGGCCCGGGTGCGGCCCGGTGCGCTGCTGAAGGCGGCCGGAGTGCTCGTCGTCGGCATGGGTATC
GGCACACTGATCGGCTGGGCGCTGCTGGAGTTCTTCCCCGGAACCCTGGCCCGCCAGGACCGCTTCCTATACGCCCTCAA
CCGCGTCAGCGCCTTCGCCGGCGCCGGTGCCGAGTCCTTCAGCGGCCATCCGCACGTCTTCGTCAACGCCCTGCTCGGAC
TGTTCGGCGCGGTGGCCCTGATGGTCACGGCAGTGGTGCTCTTCCAATCGCAGCGCGCCGAGAACGCGCTGACCGGTGAG
GACGAGTCCGCGATCCGCGGGCTGCTCGAGCTCTGCGGCAAGAACGACTCCCTGGGCTACTTCGCCACACGGCGCGACAA
GGCCGTGGTGTTCGCCCCGAATGCCCGCGCCGCCATCACCTACCGCGTCGAGGTCGGGGTGTGTCTGGCCAGCGGCGACC
CGATCGGCGACCCCCGAGCCTGGCCCCAGGCCATCGACGCGTGGCTGCAGCTGTGCCAGACCTATGGCTGGGCCCCGGGC
GTGATGGGCGCCAGCGCCACCGGCGCACAGGCCTTCCGTGAGGCCGGGCTCAACGCGTTGCAGCTCGGCGACGAGGCGAT
CCTGCACCCCGACCGGTTCCGGCTCTCCGGCTCCGACATGCGGGCCGTGCGCCAGGCCGTCACGCGGGCGCGCCGGGCCG
GAGTCGCGGTCCGCATGCGCCGGCACCGCGACCTGTCCGCCGACGAGATGGCCGAGGCGGTCGGGCGGGCCGACGCGTGG
CGCGACACTCAGGACGAGCGCGGGTTCTCGATGGCGCTGGGCCGCCTCGGCGACCCCGCCGACGGCGACTGCCTCCTGGT
CGAAGCGGTCCAGAACGACACCGAGGTGGTCGCGATGCTGTCGCTGGTGCCGTGGGGCTCCAACGGGGTGTCGCTGGACC
TGATGCGCCGCTCGCCTCAGTCGCCCAACGGGACGATCGAGCTGATGGTCAGCGAGTTGTGCCTGCAGGCCGAGGTCATC
GGGATCACCCGAATCTCGCTGAACTTCGCGATGTTCCGCTCCGCTTTCGAGCAGGGTGCGCAGTTGGGCGCCGGACCGGT
GGCCCGGCTGTGGCGCGGGCTGCTGGTGTTCTTCTCGCGGTGGTGGCAGTTGGAGACGCTGTACCGGTCGAACATGAAGT
ATCAGCCCGAATGGGTGCCGCGCTACGCGTGTTACGAGGATGCACGGTTGGTGCCGCGCGTCGGCGTTGCGTCGGTCATC
GCCGAAGGCTTTCTGGTGCTTCCCTTTTCGCGCCGGCACGAGCAGCCTCACACCGGCCATCACATCGCCGCGCCGGGCGC
CCTGGTGGCCACGGGAGTGCTGCACAGCGACGGATCCGCACCCGACCTGGACACCCTGCAGACGGATCTGCCCACCGAGG
ACCCCCAGTCCCGGCTGCCCGACCAGGTGCGAGTGCGGATGGCCAAGCTCAAGGCGCTGCAGGCCGAGGGGGTCGACGCC
TACCCGGTCGGTAGCCCACCGACCCACACGGTCGCGGACGCGCTCGCGGTCAGCGAGGGTGCCGAAGTGACGGTGGCCGG
GCGGGTGCTGCGGCTGCGCGATTACGGCGGCGTGCTGTTCGCCCAGTTGCGTGACTGGTCGGGCGAAGCCCAGCTGTTGC
TCGACAACTCGCTGCTGAGCGCCGGCAGCACCGCCGACTTCACGCGCACGATCGACCTCGGCGACCTGATCGAGGTGACG
GGGACGATGGGTCGCAGCCGCTCCGGTGCGTGGTCGGTGCTCGTGAGCCGCTGGCGGTTGATCGGTAAGTGCCTGCGACC
GTTGCCCGACAAGTGGAAGGGCCTGGCGGACCAGGAGGCACGGGTACGGGCCCGCTACCTCGACCTGGCGATCAACGACG
ACGCCCGCGATCTGATCCGGGCACGCAGCGGTGTTCTGCGTGCGATCCGGGAAACGTTGACGGCCAAAGGCTTTCTGGAG
GTCGAGACCCCGATCCTGCAACAGGTCCACGGCGGGGCCAACGCACGCCCCTTCCTGACCCACATCAACGCCTACGACCT
GGACCTCTATCTGCGGATCGCCCCGGAGCTGTACCTGAAACGGTTGTGCGTCGGCGGTGTCGAGCGCGTCTTCGAACTCG
GCCGCGCCTTCCGTAACGAGGGTGTGGACTTCAGCCACAATCCCGAATTCACGCTGCTCGAGGCCTATCAGGCGCACGCC
GACTACACCGTGTGGATCGACGGATGTCGTGAGCTGATCCAGAACGCCGCCCGGGCCGCCAACGGCGCAGAGGTGTTCCT
CCGGCCGACCGAGGACGGCGCACTGCAGCCCGTGGACATCTCCGGCCAGTGGAGGGTCCAGACCGTGCACGACGCCGTGT
CGGAGGCGCTGGGTGAACACATCGACAGCACCACCGATCTGAGCGCGCTGCGCCGGCTCTGCGACAGGGCGGACATCCCC
TACCGGACGCACTGGGACGAGGGCGCGGTGGTACTGGAGATGTATGAGCACTTGGTCGAGGACGGCACGGAACAGCCGAC
GTTCTACACGAACTTCCCGACGTCGGTGTCGCCTCTGACCCGGCCGCACCGCAGCATCCCGGGAGTCGCCGAGCGCTGGG
ACCTGGTCGCGTTCGGCGTCGAGCTTGCAACGGCCTACAGCGAACTCACCGACCCCGTGGAACAGCGCAGGCGCCTGCAG
GAGCAGTCCCTGCTGGCGGCCGGCGGCGATCCGGAAGCCATGGAACTCGACGAGGATTTCCTGCAGGCGATGGAGTACGC
GATGCCGCCCACCGGTGGTCTGGGCATGGGTGTCGATCGCGTCGTCATGCTGATCACCGGGCGCAGCATTCGGGAGACGC
TGCCTTTCCCGTTGGCCAGACCGCGATAG

Protein sequence :
MTSTSGMRTRPASSYRWVPAAAGWIVGVIATLSLMASISPLIRWLIKVPREFVDHYIFNFPDTSFAWAFVLALLAAALAA
RKRIAWWILVLYMVGSIGWNIVDIAGRGETWMRESGEMIGLAFHIASVVFLVLARKEFWARVRPGALLKAAGVLVVGMGI
GTLIGWALLEFFPGTLARQDRFLYALNRVSAFAGAGAESFSGHPHVFVNALLGLFGAVALMVTAVVLFQSQRAENALTGE
DESAIRGLLELCGKNDSLGYFATRRDKAVVFAPNARAAITYRVEVGVCLASGDPIGDPRAWPQAIDAWLQLCQTYGWAPG
VMGASATGAQAFREAGLNALQLGDEAILHPDRFRLSGSDMRAVRQAVTRARRAGVAVRMRRHRDLSADEMAEAVGRADAW
RDTQDERGFSMALGRLGDPADGDCLLVEAVQNDTEVVAMLSLVPWGSNGVSLDLMRRSPQSPNGTIELMVSELCLQAEVI
GITRISLNFAMFRSAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARLVPRVGVASVI
AEGFLVLPFSRRHEQPHTGHHIAAPGALVATGVLHSDGSAPDLDTLQTDLPTEDPQSRLPDQVRVRMAKLKALQAEGVDA
YPVGSPPTHTVADALAVSEGAEVTVAGRVLRLRDYGGVLFAQLRDWSGEAQLLLDNSLLSAGSTADFTRTIDLGDLIEVT
GTMGRSRSGAWSVLVSRWRLIGKCLRPLPDKWKGLADQEARVRARYLDLAINDDARDLIRARSGVLRAIRETLTAKGFLE
VETPILQQVHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHA
DYTVWIDGCRELIQNAARAANGAEVFLRPTEDGALQPVDISGQWRVQTVHDAVSEALGEHIDSTTDLSALRRLCDRADIP
YRTHWDEGAVVLEMYEHLVEDGTEQPTFYTNFPTSVSPLTRPHRSIPGVAERWDLVAFGVELATAYSELTDPVEQRRRLQ
EQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-160 42
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-161 42
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-161 42
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 5e-161 42