Gene Information

Name : Mycch_1057 (Mycch_1057)
Accession : YP_006451546.1
Strain : Mycobacterium chubuense NBB4
Genome accession: NC_018027
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1058998 - 1060521 bp
Length : 1524 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACTGTGTATGCCCGACCGGGTGCCGACGGCTCGCTGATGTCGTTCAAGCCCCGCTACGAGAACTTCATCGGCGGCCA
GTGGGTACCGCCTAACGCCGGACGCTACTTCGAGAACCCGACGCCGGTGACCGGCGAGGCGTTCACCGAGGTGGCCCGCT
CCGACGAGTCCGACATCGAGAAGGCCCTCGACGCCGCGCACGCCGCCGCCCCCGCCTGGGGCAAGACCGCAGCGGCCGAG
CGCGCCGTGATCCTCAACAAGGTCGCGGACCGCATCGAGGAGAACCTCGAGTCGATCGCGCTGGCCGAGTCGTGGGACAA
CGGCAAGCCGATCCGCGAGACGCTGAACGCCGACATCCCGCTGGCCGTGGACCACTTCCGCTACTTCGCCGCGGCGATCC
GATCCCAGGAGGGATCGCTCAGCGAGATCGACGACGACACCGTCGCCTACCACTTCCACGAACCCCTCGGCGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGACGTGGAAGCTGGCCCCCGCGCTGGCCGCGGGCAACGCGGTGGT
GCTCAAGCCCGCCGAGCAGACGCCCGCGTCGATCCTCTACCTGATGGAGATCATCGCCGACCTGCTGCCCGCCGGCGTGG
TCAACGTCGTCAACGGGTTCGGCGTCGAGGCCGGCAAGCCGCTGGCCTCGAGCAACCGGATCGCCAAGATCGCGTTCACC
GGCGAGACCACCACCGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATCCCGGTGACGCTGGAGCTGGGCGGCAA
GAGCCCGAACATCTTCTTCAACGACGTGCTGGCCGCCGCGGACAGCTACCAGGACAAGGCGCTCGAGGGCTTCACGATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCTCGCTGATCCAGTCCGACATCTACGACGAGTTCCTCGCG
CTGGCCGCGATCCGCACCAAGGCCGTCCGGCAGGGCGACCCGCTGGACACCGAGACGATGATCGGTGCGCAGGCGTCCAA
CGACCAGCTCGAGAAGATCCTGTCCTACATCGAGATCGGCAAGAGCGAGGGCGCCCAGGTGGTCACCGGCGGCGAACGCG
CTCAGCTCGGCGGTGACCTGAACGGCGGATACTACGTCGCCCCAACGATTTTCACCGGACACAACAAGATGCGGGTGTTC
CAGGAGGAGATCTTCGGCCCGGTGGTGGCGGTGACGTCGTTCTCCGATTACGACGAGGCGATCAGCATCGCCAACGACAC
GCTGTACGGACTCGGGGCCGGTGTGTGGAGCCGCGACGGCAACACCGCCTACCGCGCCGGGCGCGACATCAAAGCCGGCC
GGGTGTGGACGAACTGCTACCACCAGTACCCCGCGCACGCCGCGTTCGGTGGCTACAAGCAGTCCGGCATCGGCCGGGAG
AACCACAAGATGATGCTCGACCACTATCAGCAGACCAAGAACCTGCTGGTCAGCTACAGCGACAAGGCGCAGGGCTTCTT
CTAG

Protein sequence :
MTVYARPGADGSLMSFKPRYENFIGGQWVPPNAGRYFENPTPVTGEAFTEVARSDESDIEKALDAAHAAAPAWGKTAAAE
RAVILNKVADRIEENLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAAAIRSQEGSLSEIDDDTVAYHFHEPLGVVG
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASILYLMEIIADLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAAADSYQDKALEGFTMFALNQGEVCTCPSRSLIQSDIYDEFLA
LAAIRTKAVRQGDPLDTETMIGAQASNDQLEKILSYIEIGKSEGAQVVTGGERAQLGGDLNGGYYVAPTIFTGHNKMRVF
QEEIFGPVVAVTSFSDYDEAISIANDTLYGLGAGVWSRDGNTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRE
NHKMMLDHYQQTKNLLVSYSDKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-139 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-148 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-148 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-148 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-147 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycch_1057 YP_006451546.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 4e-140 63