Gene Information

Name : Desti_0842 (Desti_0842)
Accession : YP_006445830.1
Strain : Desulfomonile tiedjei DSM 6799
Genome accession: NC_018025
Putative virulence/resistance : Virulence
Product : peptide arylation enzyme
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 986748 - 988436 bp
Length : 1689 bp
Strand : +
Note : PFAM: AMP-binding enzyme; TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase

DNA sequence :
ATGGAAGGCTTCACACCGTGGCCCATGGATTTCGCTGAGAAGTATCGATCCGCGGGCTATTGGATCGATCAGACAATAAG
CGAGGTCATGGATGAGAGCTTTGCCAAATATGCGTCGCGAACGGCGCTCATCACATCAGGAGGACGAGAGTTCAAGTACA
GCGACCTGGGAAATCTCGCCACTCGACTCGCTCTTCATCTAGTAAATCTCGGTCTGAGGCCCTATGACCGTCTCATCCTG
CAGATGCCCAACATCCCCGAGGTGGCGATCACGTACCTCGCTGCTCTGAAAGCCGGGGTCATTCCGATAATGGCCCTCTT
TGCTCACAGAGAAGCGGAAATCGGCTTTTTTGCCGAGCTGGCCGAGGCTCGAGCAATTGCAGTCGGAACTGCCTGGCGTG
GATTCGATTATGAAGAGATGGCTGCAAATGTGCAAACCAAGAACCCTCAGTTGAAAATGGTCCTCGTTGCCGGGGGTGAA
CCCAAGAAAGGCAACTATTCCATTGATGCCATGCTTCAGGATCCCATCGAGAAGCGTATGGGGCTGAACGAGCTTCCCAG
ACAGGACCCCAATCTTCCCGCGGTTCTTCTTCTTTCAGGTGGAACGACAGGTATTCCCAAACTTATTCCGAGAACGCATA
ACGACTACACATACAACTTCCTCTGCAATGCAGATATTTGCGGGCTGAACGAGAATACGGTCAGTCTCGTTGCCATCCCA
CAGGAACACAATTTTGCAGTAGCGTGTCCCGGATTAAAAGGCGTCCTCTCCAAAGGCGGTTGCGAGATTCTCTCGGATAA
TCCGAGCCCTGAAGCGATGATGGAGCTGATTGCCAAGCATCATGTCACACATTGCATTGCAGTGCCGACCATGATTGTGG
GTATGCTGAATCATCCCAACCGCCGGAAGTACGACATGAGCTCTCTGGAAGTGATCCTGACCGGTGGCTCGAAATTAAAC
CCGGAAGTCGCCTTGCGTATAAAGCCGGAACTGGGATGCGATGTACAGCAGGTACTCGGCATGGCCGAAGGCCCCCTGTA
TTGGACACGAAGAGACGACCCACTGGAAGTACAGCTCCACACTCAGGGGCGTCCACAATCTCCGGGGGATGAATTCAGGA
TCGTCGACCCGGTCACGGAGACGGATGTCCAACAAGGGGAGGTGGGGGAACTTTGGTGTCGAGGGCCGCACATCATCAGA
GGCTACTATCGGGCGCCCGATCACAATGCCAAGGCATTTACGGAAGAGGGTTTTTACAAATCAGGCGACCTCGTTCGCCT
GCATCACACAGGCAACGTGGTGGTCGAAGGTCGAATCAAGGACTGCATCAACCGAGGTGGCGAAAAGATCAGTGCTGAAG
AGGTCGAAGATCATATTCTGGCCCATCCTGCAGTAGCCAACTGTGCCTATGTCGCTATGCCGGATCCTCTTATGGGAGAG
CGAGCGTGTGTATACGTAATCCCGCGGCATGATTCGTCCATCAACCTTAAAACCTTGAATGAGTTTCTCCTGCAAGAGAG
AAAAATAGCAAAATTCAAGCTACCTGAACGCCTGGAGTTAGTTGATGCCTTTCCCCTCACCCCTGTTGGAAAGGTCAACA
AGAAAGCCCTGCGTCAGATGATAGCAGAGAGGGTAGAGCTGGAACGCCAAGCCAGTGGCGGCAAGCTCGACGGAACGAAG
ATACGATGA

Protein sequence :
MEGFTPWPMDFAEKYRSAGYWIDQTISEVMDESFAKYASRTALITSGGREFKYSDLGNLATRLALHLVNLGLRPYDRLIL
QMPNIPEVAITYLAALKAGVIPIMALFAHREAEIGFFAELAEARAIAVGTAWRGFDYEEMAANVQTKNPQLKMVLVAGGE
PKKGNYSIDAMLQDPIEKRMGLNELPRQDPNLPAVLLLSGGTTGIPKLIPRTHNDYTYNFLCNADICGLNENTVSLVAIP
QEHNFAVACPGLKGVLSKGGCEILSDNPSPEAMMELIAKHHVTHCIAVPTMIVGMLNHPNRRKYDMSSLEVILTGGSKLN
PEVALRIKPELGCDVQQVLGMAEGPLYWTRRDDPLEVQLHTQGRPQSPGDEFRIVDPVTETDVQQGEVGELWCRGPHIIR
GYYRAPDHNAKAFTEEGFYKSGDLVRLHHTGNVVVEGRIKDCINRGGEKISAEEVEDHILAHPAVANCAYVAMPDPLMGE
RACVYVIPRHDSSINLKTLNEFLLQERKIAKFKLPERLELVDAFPLTPVGKVNKKALRQMIAERVELERQASGGKLDGTK
IR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-89 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 43
ybtE CAA21394.1 - Virulence HPI Protein 1e-89 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-90 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-89 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-90 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-89 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desti_0842 YP_006445830.1 peptide arylation enzyme VFG0168 Protein 6e-94 45
Desti_0842 YP_006445830.1 peptide arylation enzyme VFG1817 Protein 4e-88 42