Gene Information

Name : Desti_1100 (Desti_1100)
Accession : YP_006446078.1
Strain : Desulfomonile tiedjei DSM 6799
Genome accession: NC_018025
Putative virulence/resistance : Resistance
Product : cation/multidrug efflux pump
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1315541 - 1318567 bp
Length : 3027 bp
Strand : -
Note : PFAM: AcrB/AcrD/AcrF family

DNA sequence :
ATGAATCTTGCGGGATATGCCATTCGACACAATGTCGTCACGCTTGTGTCCATCATTCTGGTCACCGTGGGAGGAATTCT
GGCGTACGGAAAACTCGGTCGTTTGGAAGACCCGGAGTACACGATCAAGGAAGCAGTGATTTATACCGAATATCCGGGGG
CCACCGCCGAGGAAGTTGAACTGGAAGTCACCGAGCCTCTGGAGACAGCCATCCAACAACTAAAACAGTTGAAGGAGGTG
CGGTCCATTTCCCGGCCTGGACTCTCGATCATCTTCGCTGAGATGCAGGAAATCTATGACAAAGAAACTCTTCCGCAAGT
GTGGGACGAACTCCGCCGAAGGGTCGACACAGCTGCGAGTCACTTGCCTCCCGGCTGCAAGGCCTCGGTTGTTAACGACG
ATTTCGGAGACGTGTATGGTGTCCTCTTTGCCATCACAGGCGACGGTTACTCCCAGCATGACTTGAAAGAGGTCTCAGAG
GACCTGCGCCGAGAGCTGTTATTATGCCCGAACGTTGGGCGTATCGACTTCTGGGGCATACACAGCGAAGCAATATATGT
CGAAGTAGATCGGGTCAAGCTTGCCCAACTCGGACTGCCGCCCACGGCGATTTTTGATGCGATCAACCAACAGAACGCGG
TCACAGAAGCGGGACGGGTCAAAGTAGGCCCCGAAGATGTTCGTCTCCGCGTTACTGGCGATTATTCGCGCATAGAAGAC
CTGGGGGAACAACTTGTTCAAGGCGGATCGCAAAGACGCATGATCCGCTTGAAGGATGTGGCTCGAATCGAGCGAGGGTA
TCTCGATCCACCCAACGAAATCTTGCGCTGGAACGGAAGCACCGCTGTCGGCCTCGGCGTTTCCACGGGTTCCGGGGGAA
ATGTCATTGCCATGGGCGAAGCGATAAAGGAACGACTCGCCCAATTGGAGGCACGGATTCCTGTAGGCATCGAAATCCAT
CCGATCGCGCACCAGGGTGAAAAGGTGAGGGAAGCGGTGCGAGAGTTCGTGCTTGGCCTCTTCGAGGGTGTGCTCATTGT
GATTCTGCTCCTGGTGGTCTTTATGGGGCTGCGCGAAGGGTGCATCATGGGCGCGGTTCTTCTCATCATCGTTTTTGTCA
CGTTTTTGTGCATGTACACGTTGGGTATCACGTTGCAGCGCATCTCGCTGGGCGCGTTGATCATTGCAATGGGAATGCTG
GTTGACGACGCCATTGTGGTAGTGGAGGGAACCGTTATCAAATCGCATCAAGGCATGAGTAGATCGCAAGCGGCTGAAAA
AACGGTGGCAGAAACCCAATGGCCACTGCTCGGAGCGACGGCCATCGCGATCCTTGCATTCGCGGCCATCACGCTTTCAA
AAGACATGACCGGTGAATGGTTGAAAAGCCTTTTCCAAGTTATATGCCTGTCGCTCGGTTTGAGCTGGGTCTTCGCAATC
ACGGTTACACCATACCTGTGCGTCACTTTTCTCCCATTAGCAAAACGTAGCGAAAAAGATCCCCATGATAATCCGTTCTA
TCGCTCGTACCGAAAATTGGTAGGGTGGTGCATCGATCATCGCTGGATCACGCTGGCTGTGGTGATGGCCCAGTTGCTGA
TTGCCATATGGGGTTTCGGATTCGTCAAGCAGGACTTCATGCCGGACATGAATCGCCCTCAGTTCACGTTGGATGTTTGG
CTGCCGGAAGGTACCCATATTTATGAGACCTCCAACCAAGTGGCCGCCATTGAAACGTTCGTTCGCACCCTGGATGGCGT
CAGGGACGTAACGAGCTTTGTCGGACGCGGCCCACTGCGATTTCTGTTGACATACGAACCGGAAATGCAGAATAGCGCCT
ACGGTCAACTGCTTGTAACTGTAGATCATTATGAGAGAATCTCGACACTGCGGGAGCAGCTCACAACCTACTTGAAAAAT
CATCATCCCAACGCTGTCACGAGCGTGGATGCATTCAAGCTAGGACCCGGTGGTGGAGCTGTGGTAGCGCGTCTCAGTGG
GCATGATGTGAATACACTGCGTGATTTGGCCGAGAAGGTCAGAGCTGTCATGTACGCACATGGCAACACCCGTAGCATAA
GAACTGATTGGGGAGATCGCGTTAAAGTCGAATCACTGCGTCTGGCAGACGCGCGCTCGCGCGAGATTGGTGTTACTCGT
CCAGACATTGCCCGATCTCTGGCCATGAACTTTTCAGGTTCTGCAGCCGGATTGTACCGTAAAGGAGATGACCTGCTGCC
GGTCATGCTTCGCCCCCTTCGCGATCAGCGATGCGGCGTTGACAACGTGGATAACGTCCAGGTTTGGAGTACTGCGCAGA
GTAGATGGGTTCCTATTGACCAGGTAACGGAGGGAGCTGTGAGTTGCTGGGAAGATCCTGTGATCCATCGGCTGAATCGC
ATTCGAACAATCCGCGTGTCCTGCAAGCAAGTGACTGGAACAACCGATACATTATTTCGACAGTTGCGCATGCCAATCGA
AAGCATCGAATTGCCCCCAGGATATAAGCTTGAATGGGGTGGTGAACACGAGGAGCATGAGGAAGCGAACCAGAAGCTCA
TGTCAAACGTCCCCATCGCATTCATTGCCATGTTCCTCATCTCGATCATGTTGTTCAATACATTTCGCCACCCCCTCATC
ATTTTCCTCTGCCTTCCGTTGGCCGTGATCGGTGTAACGGCTGGAATGCTCCTTACCGCAAAACCTTTTGGCTTCATGGC
TATGTTGGGCTTTCTCAGCCTGTCGGGCATGCTCATAAGAAACTCAATCGTTCTGCTCGATCGGACAAACCTTGAAATAG
CAGAGGGCAAGAGTCGCTACGGAGCTGTCATCGACGCTGCCGTGAGCCGCGTGCGACCTGTAAGCATGGCCGCGTTCTCC
ACGGTACTTGGGATGACTCCGCTGTTGTGGGATCCTTTCTTCGCTCCCATGGCAGCGACCATTATGGGAGGCTTAACTTT
CGCAACAATACTGACTCTCGTTGTTGTACCCGTGCTATATAGCACATTTTTCAGAATTCGCCGGTAG

Protein sequence :
MNLAGYAIRHNVVTLVSIILVTVGGILAYGKLGRLEDPEYTIKEAVIYTEYPGATAEEVELEVTEPLETAIQQLKQLKEV
RSISRPGLSIIFAEMQEIYDKETLPQVWDELRRRVDTAASHLPPGCKASVVNDDFGDVYGVLFAITGDGYSQHDLKEVSE
DLRRELLLCPNVGRIDFWGIHSEAIYVEVDRVKLAQLGLPPTAIFDAINQQNAVTEAGRVKVGPEDVRLRVTGDYSRIED
LGEQLVQGGSQRRMIRLKDVARIERGYLDPPNEILRWNGSTAVGLGVSTGSGGNVIAMGEAIKERLAQLEARIPVGIEIH
PIAHQGEKVREAVREFVLGLFEGVLIVILLLVVFMGLREGCIMGAVLLIIVFVTFLCMYTLGITLQRISLGALIIAMGML
VDDAIVVVEGTVIKSHQGMSRSQAAEKTVAETQWPLLGATAIAILAFAAITLSKDMTGEWLKSLFQVICLSLGLSWVFAI
TVTPYLCVTFLPLAKRSEKDPHDNPFYRSYRKLVGWCIDHRWITLAVVMAQLLIAIWGFGFVKQDFMPDMNRPQFTLDVW
LPEGTHIYETSNQVAAIETFVRTLDGVRDVTSFVGRGPLRFLLTYEPEMQNSAYGQLLVTVDHYERISTLREQLTTYLKN
HHPNAVTSVDAFKLGPGGGAVVARLSGHDVNTLRDLAEKVRAVMYAHGNTRSIRTDWGDRVKVESLRLADARSREIGVTR
PDIARSLAMNFSGSAAGLYRKGDDLLPVMLRPLRDQRCGVDNVDNVQVWSTAQSRWVPIDQVTEGAVSCWEDPVIHRLNR
IRTIRVSCKQVTGTTDTLFRQLRMPIESIELPPGYKLEWGGEHEEHEEANQKLMSNVPIAFIAMFLISIMLFNTFRHPLI
IFLCLPLAVIGVTAGMLLTAKPFGFMAMLGFLSLSGMLIRNSIVLLDRTNLEIAEGKSRYGAVIDAAVSRVRPVSMAAFS
TVLGMTPLLWDPFFAPMAATIMGGLTFATILTLVVVPVLYSTFFRIRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desti_1100 YP_006446078.1 cation/multidrug efflux pump BAC0519 Protein 0.0 47
Desti_1100 YP_006446078.1 cation/multidrug efflux pump BAC0428 Protein 0.0 45
Desti_1100 YP_006446078.1 cation/multidrug efflux pump BAC0425 Protein 0.0 44
Desti_1100 YP_006446078.1 cation/multidrug efflux pump BAC0526 Protein 2e-176 42