Gene Information

Name : Mycch_5946 (Mycch_5946)
Accession : YP_006442877.1
Strain :
Genome accession: NC_018022
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 613751 - 615268 bp
Length : 1518 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family; manually curated; IMG reference gene:2506874477_SP

DNA sequence :
ATGGTGTTTGCACGGCCGGGGGCTGAGGGCAGCGTGGTTGAGTTCGCTGACCGGTACGAGAATTTTATTGGCGGTGACTG
GGTCGCGCCGGTTGAGGGGGCGTATTTCGATAATTCGTCACCGGTGACCGGTGAGGTGTTCACGCAGGTGGCGCGGTCGT
CGGCGGCCGATGTTGAGTTGGCGTTGGACGCCGCGCACGCCGCGGCGGGCAGATGGGCGGCGACCTCCACGGCGGAGCGT
TCTGGGGTGTTGCTGAAGATCGCTGATCGCATGGAGCAGCATCTGGAATCGTTGGCGGTGGCCGAGACGTGGGATAACGG
CAAGGCGGTGCGGGAAACCCTGGCCGCAGATCTGCCGTTGGCGGTGGATCATTTACGGTATTTCGCCGGAGTGCTGCGCG
CCCAGGAGGGTTCGATCGCCCAGATCAACGAGGACACGGTGGCCTATCATTTCCAGGAGCCGTTGGGTGTGGTGGCGCAG
ATCATTCCGTGGAACTTCCCCATCTTGATGGCGATCTGGAAGGTGGCCCCGGCGCTGGCGGCCGGTAACACGGTGGTGCT
CAAGCCTGCTGAGCAGACCCCGGTGTCGATTCTGAAGGTCATCGAGCTGATCGCGGATCTGTTGCCACCTGGTGTGCTCA
ACGTGGTCAACGGGTTCGGGGTAGAGGCGGGTAAGCCGCTGGCCTCCAGTGCGCGGGTGGCCAAGGTGGCGTTCACCGGG
GAGACCACCACGGGGCGGCTGATCATGCAGTACGCCAGCGAGAACATCATCCCGGTGACCTTGGAGCTGGGTGGTAAGAG
CCCGAATATCTTTTTGGCCGATGTCGCTGCAGCCGATGATGAGTTTTTGGACAAGGCGGTCGAGGGTTTTGTGATGTTTG
CCCTCAACCAGGGTGAGGTGTGCACGTGTCCGTCGCGGGCGTTGATCCATTCGTCGATCTATGACGAGTTCATCAGCCGC
TGTGTGGCGCGCACCGAAGCGATCGTCAGTGGTGACCCGTTGAATCCGGCCACCATGATCGGCGCACAGGCCAGCAATGA
TCAGTTCGAAAAAATCATGTCCTACATCGACATTGGCCGCAAAGAGGGGGCGCAGGTGCTCACCGGTGGTGGGGCGCGCA
AGGTTGCCGAGTATCCCGGCGGCTATTACGTGGAACCCACCATCTTCAAGGGCACCAACGATATGCGGATCTTCCAGGAG
GAGATCTTTGGACCCGTGGTGTCGGTGACGACGTTCGATTCCACCGATGAGGCGCTCAAGCTGGCCAACGACACCCTCTA
CGGCCTAGGTGCGGGAGTGTGGACCCGCGATTCCAACACCGCCTACCGGTTAGGCCGGGGTATCAAGGCCGGCCGCGTGT
GGACTAACTGCTACCACGACTACCCCGCGCACGCCGCGTTCGGTGGCTACAAGAAATCCGGCATCGGCCGCGAATGCCAC
AAGATGATGCTCGACCACTACCAACAAACCAAAAACCTGTTGGTCAGCTACTCACCGAACAAGCTCGGCTTCTTCTGA

Protein sequence :
MVFARPGAEGSVVEFADRYENFIGGDWVAPVEGAYFDNSSPVTGEVFTQVARSSAADVELALDAAHAAAGRWAATSTAER
SGVLLKIADRMEQHLESLAVAETWDNGKAVRETLAADLPLAVDHLRYFAGVLRAQEGSIAQINEDTVAYHFQEPLGVVAQ
IIPWNFPILMAIWKVAPALAAGNTVVLKPAEQTPVSILKVIELIADLLPPGVLNVVNGFGVEAGKPLASSARVAKVAFTG
ETTTGRLIMQYASENIIPVTLELGGKSPNIFLADVAAADDEFLDKAVEGFVMFALNQGEVCTCPSRALIHSSIYDEFISR
CVARTEAIVSGDPLNPATMIGAQASNDQFEKIMSYIDIGRKEGAQVLTGGGARKVAEYPGGYYVEPTIFKGTNDMRIFQE
EIFGPVVSVTTFDSTDEALKLANDTLYGLGAGVWTRDSNTAYRLGRGIKAGRVWTNCYHDYPAHAAFGGYKKSGIGRECH
KMMLDHYQQTKNLLVSYSPNKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 61
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-141 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-149 61
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 2e-97 60
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 1e-97 59
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 1e-96 59
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 1e-96 59
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 2e-97 59
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 2e-97 59
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 2e-97 59
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 2e-97 59
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-68 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycch_5946 YP_006442877.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 9e-142 61