Gene Information

Name : Fleli_4022 (Fleli_4022)
Accession : YP_006436115.1
Strain : Flexibacter litoralis DSM 6794
Genome accession: NC_018018
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4835649 - 4837100 bp
Length : 1452 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGAAAAAACTAAATAACTACATAGGAGGAGAATTTATAAATCCTTTTTCAGATAATTACATTGAAAACATCAACCCAGC
CACAGGAAAAGTTTTTTCATTGATTGCTGATTCTGATGAAAATGATGTAAATTTAGCTGTTGAAGCTGCAAAAGTAGCAT
TTCCAGAATGGTCTTCAAAAGGAGCAGAATATCGCTCCAAATGGCTTTTAAAATTAGCTAATTATATAGAAGAGAATGTA
GAAAAATTTGCACAAGCCGAAACTCAAGACAATGGAAAACCTATTTCTCTTTCTTGTACTATGGATATTCCTCGTGCTGT
CCAGAATTTATCATTTTTTGCAACAGCTATTTTGCATGATAAAGACGAAGCTCATCATACTTCTACAAATATTTTGAATT
ATACCTTACGCCAACCTTTAGGGGTTGTGGGTTGTATTTCACCTTGGAATTTGCCTTTGTATTTATTTACTTGGAAGATT
GCGCCTGCACTTGCTAGTGGTAATTGTGTTGTTGCCAAACCCTCTGAACTCACACCTTATACAGCTTATTTGCTTTCGGA
AGCCTGTCAAGCAATAAATTTTCCTAATGGTGTTCTGAATATTGTACATGGCTACGGACACCAAGCAGGTGCTGCCATTA
CTGCACACAAAGACACAAAGGCAATTTCTTTTACAGGAGGAACACAAACAGGAAAAACGATTGCATCAATAGCTGCACCT
ATGTTCAAAAAACTCTCTTTAGAATTAGGTGGAAAAAATGCAACTATTATTTTTGCAGATTCAGACCTAGAAGAAGCAAT
CGAAACAGCCGTAAAAGCAGCGTTTACTAATCAAGGACAAATTTGTTTATGTGGTTCTAGGATTTTGATAGAAAAAGTAA
TTTATGAAGAGTTTAAAATAAAATTCATAGAAAAAGTAAAAGAATTAAAAGTAGGCGACCCATTAGAGAAAAATACGCAA
CAAGGAGCAACAGTTTCGAAAGCACATCAAGAAAAAGTTTTATCCTATATAGAAATTGCCAAAAATGAAGGAGGAATTAT
TTTGACAGGAGGAAATAAAGTAGCTTCTGAAAACCTTCCAAACAGATGTAAAGACGGATTTTTTATTGAACCAACTGTTA
TTGAAGGCTTATCACCTTTTTGCAGAACCAATCAAGAAGAAATTTTTGGAGCAGTAACTACGCTTATTCCTTTTGAAAAT
GAAAATGAAGCCATAGAATTTGCCAACTGTACACCTTATGGACTTTCAGCATCTGTTTGGACACAAAATTTATCCAGAGC
GCACCGAGTAGCCAGTCAATTAGAAACAGGAATTGTTTGGATAAATACATGGTTATTGCGTGATTTGAGAACGCCTTTTG
GAGGTGCAAAACAATCTGGAGTAGGACGAGAAGGAGGTTATGAAGCCCTAAACTTTTTTACAGAAGAGAAAAATGTGTGT
ATAAAATTTTAG

Protein sequence :
MKKLNNYIGGEFINPFSDNYIENINPATGKVFSLIADSDENDVNLAVEAAKVAFPEWSSKGAEYRSKWLLKLANYIEENV
EKFAQAETQDNGKPISLSCTMDIPRAVQNLSFFATAILHDKDEAHHTSTNILNYTLRQPLGVVGCISPWNLPLYLFTWKI
APALASGNCVVAKPSELTPYTAYLLSEACQAINFPNGVLNIVHGYGHQAGAAITAHKDTKAISFTGGTQTGKTIASIAAP
MFKKLSLELGGKNATIIFADSDLEEAIETAVKAAFTNQGQICLCGSRILIEKVIYEEFKIKFIEKVKELKVGDPLEKNTQ
QGATVSKAHQEKVLSYIEIAKNEGGIILTGGNKVASENLPNRCKDGFFIEPTVIEGLSPFCRTNQEEIFGAVTTLIPFEN
ENEAIEFANCTPYGLSASVWTQNLSRAHRVASQLETGIVWINTWLLRDLRTPFGGAKQSGVGREGGYEALNFFTEEKNVC
IKF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-78 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-63 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-66 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-66 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-66 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-66 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fleli_4022 YP_006436115.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 4e-64 42