Gene Information

Name : Fleli_0174 (Fleli_0174)
Accession : YP_006432466.1
Strain : Flexibacter litoralis DSM 6794
Genome accession: NC_018018
Putative virulence/resistance : Virulence
Product : helicase, type I site-specific restriction-modification system restriction subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 200927 - 203968 bp
Length : 3042 bp
Strand : +
Note : PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family

DNA sequence :
ATGTACTCCAAAACTAATGAAATCGCTTTAGAAATTGCTATTGAAAAATATCTAGTAGGTATTTCTTCCGAAGAATTGAA
AACAAATGAAACTCATCATACAGATAATTTGTATGGTGGCGACCATTTTTATAGTGGAAAAAGTATAGATTTTAATAAAC
GCTATGCTATTGATGAACATCGTTTTTGGCATTTTTTGGAAAACACACAAGAAGAAGAACTCAAAAAATTACAGCGTTCT
GCCGATTGGAAACTAAAAATAATGGAGCGTTATGACCGTACCGTAAAAAAATACGGTTTGTTGCGTGTTTTGCGTAAAGG
ATTAGATGTAGAAGACGCTCATTTTACTTTCTTTTATCAATATCCGTTGGTAAGTAGTAGCCAGTCGGTAAAGGATAATT
TTGAAAAAAATGAATTTAGTCTTACTCGTCAGCTTCATTACAATTCGGACAAACCAGCCGAATCCATAGACATTGTTTTG
TTTGTCAATGGTTTGCCTATTTCTACTATTGAACTCAAAAACCCTTGGACAGGACAGACAGCAAAAGTAGAAGGCATTCG
TCAGTACCAAAAAGACAGAGATACAAATCAGCCTTTGCTTAATTTTGGTAGATGTTTGGTTCATTTTACGCTAGATACTG
ATGAGGCGTATATGACAACAAAATTAGTAGGCGAAAAAACATTTTTTCTTCCTTTCAATAAAGGAAACAATAACGGAAAA
GGAAACCCAGTCAATCCAAATGGACATAAAACGGCTTATGTTTGGGAAGAGGTTTATACTCGTAAGAGTTTGGCAAATAT
CATTCAACATTTTGTCCGTTTTGATGGAAAATCTACTGATGCACTAAGCAAAAGAACGTTGTTTTTTCCACGTTATCATC
AAATGGACGTAGTAAGAAAAATTGTACAAGACACCACACAAAAAGGAGTAGGCAAAACCTATTTGATTCAGCATTCAGCA
GGCTCTGGAAAGTCTAATTCAATTACATGGTTAGCTTATCAGCTTATAGAAGTCTATCCGACCGAAAGCACAAACTCTAT
TGAGCGTCCGTTATTTGATTCTGTAATTGTAGTAACAGATAGACGTTTATTAGACAAACAGCTTCGCCAAAACATCAAAG
AATTTTCGGAAGTCAAAAATATTGTCGCTCCTGCTTTTTCCTCAAAAGAATTGAGAGAAAGTTTAGAACAAGGAAAGAAA
ATTATCATTACAACGATACAAAAATTCCCTTTTATCATTGATGGAATAGCAGATTTGAGTAAAAGTCGTTTTGCTGTAAT
TATTGATGAAGCGCATAGTTCACAAGGAGGTTCGACAGCAGGAAAAATGAATGCTGCGATGGGAAGTTCAGAGGAAAACA
GCAATGAAGACAGCGAAACAGAGGACATTCAAGACAAAATCGTAAAAGCGATGCAGGCTCGTAAAATGAAAGGCAATGCT
TCTTATTTTGCTTTCACAGCCACGCCAAAAAACACGACTTTAGAGAAGTTTGGAGAATTACAAACTGATGGTTCTTTCAA
GCCTTTTCATTTGTACTCAATGAAACAAGCGATTGAAGAAGGATTTATTTTAGATGTAATTGCAAATTATACGACGTATC
AAAGTTATTACGAAATTCAAAAATCTATTGAAGACAATCCTTTATTTGATACCAAAAAGGCGCAGAAAAAACTAAAAGCA
TTCGTAGAAACAGATAAACGAACCATTAATACAAAAGCAGAAGTAATTTTTGAGCATTTTATGAGTCAAGTAGTCAATAG
AAAAAGACTCAAAGGAAAAGCAAAAGGAATGGTCATTACTCAAAATATAGAAACGACTGTTCGTTATTATACTGCTCTGA
AAAGAATTTTAGAAGAAAAAGGAAATCCATTTAAAATAGTGGTTGCTTTTTCAGGAAAAAAAGAAGTTGATGGTATCGAA
CAGACAGAAACATTATTAAATGGTTTTTCCGAATCTGATACAAGAGAAAATTTTGATACTGATGAGTATAGATTATTGGT
TGTAGCCAATAAATATTTGACAGGTTTTGACCAGCCTAAATTGTGTGTTATGTATGTTGATAAAAAACTACAAGGCGTTT
TGGCAGTTCAAGCACTTTCTCGTATCAATAGAGCAGCCAGTAAGTACGGCAAAAAAACAGAAGATTTGTTTGTTTTAGAT
TTTTTCAACTCTATTGTAGATATAAAAGCATCTTTTGACCCTTTTTATACTTCCACTACACTAAGTGAAGCCACAGATAT
AAATGTTTTACACGAACTCAAATCTAGTCTTGATGAAGTAGGTGTTTATGAAACAAGTGAAATAGAAGAGTTTGTAGAAA
AATTCTTTCAAGGCAAAGATGCACAAGGGTTAAGTCCGATTATAGACACAGCAGCTGCTCGTTTTAATGAAGAATTGGAA
CTAGAAGACAAAGAAAAAGCAGATTTTAAAATTAAAGCCAAACAGTTTGTAAAAGTATATGGACAAATTTCTTCTATCAT
TCCGTATGAAATGGTTGCTTGGGAAAAACTATTTTGGTTTCTCAAATTCTTAATTCCTAAACTTATCATCAAAACAAAAG
ATGATGACATTATAGATGAGCTTTTAGAATCAGTTGATTTATCTACGTATGGATTAGAGAGAAAAACATTAAGTCATTCC
ATTGTTTTAGATGATGAAGAGTCAGAACTAAAACCTCAAAATGCAAATCCTAGAGGAGCGCATGACAGTGAAGATGAACA
TGATTTATTAGATGAGATTATCAATACTTTCAATCAAAGATGGTTTCATGGGTGGAATGTAACACCAGAAGACCAACGAG
TAAAGTTTGTAACTCTTAGCAAACATGTACAAGCTCACCCAGACTTTGAAACAAAAGTAGCCAACAACAAAGACATACAA
AATAGAGAAATTGCTTTTCAAAAAATCTTAGAGGAAGTAATGATGCAACAGCGCAAAAAAGAGTTGGATTTATACAAACT
CTACACACAAGATGATTCTTTTAGACAAGCCTTTTTTGATACTATGAAACAAATGATGGGTAATTCTTCATCTTCTTTGT
AG

Protein sequence :
MYSKTNEIALEIAIEKYLVGISSEELKTNETHHTDNLYGGDHFYSGKSIDFNKRYAIDEHRFWHFLENTQEEELKKLQRS
ADWKLKIMERYDRTVKKYGLLRVLRKGLDVEDAHFTFFYQYPLVSSSQSVKDNFEKNEFSLTRQLHYNSDKPAESIDIVL
FVNGLPISTIELKNPWTGQTAKVEGIRQYQKDRDTNQPLLNFGRCLVHFTLDTDEAYMTTKLVGEKTFFLPFNKGNNNGK
GNPVNPNGHKTAYVWEEVYTRKSLANIIQHFVRFDGKSTDALSKRTLFFPRYHQMDVVRKIVQDTTQKGVGKTYLIQHSA
GSGKSNSITWLAYQLIEVYPTESTNSIERPLFDSVIVVTDRRLLDKQLRQNIKEFSEVKNIVAPAFSSKELRESLEQGKK
IIITTIQKFPFIIDGIADLSKSRFAVIIDEAHSSQGGSTAGKMNAAMGSSEENSNEDSETEDIQDKIVKAMQARKMKGNA
SYFAFTATPKNTTLEKFGELQTDGSFKPFHLYSMKQAIEEGFILDVIANYTTYQSYYEIQKSIEDNPLFDTKKAQKKLKA
FVETDKRTINTKAEVIFEHFMSQVVNRKRLKGKAKGMVITQNIETTVRYYTALKRILEEKGNPFKIVVAFSGKKEVDGIE
QTETLLNGFSESDTRENFDTDEYRLLVVANKYLTGFDQPKLCVMYVDKKLQGVLAVQALSRINRAASKYGKKTEDLFVLD
FFNSIVDIKASFDPFYTSTTLSEATDINVLHELKSSLDEVGVYETSEIEEFVEKFFQGKDAQGLSPIIDTAAARFNEELE
LEDKEKADFKIKAKQFVKVYGQISSIIPYEMVAWEKLFWFLKFLIPKLIIKTKDDDIIDELLESVDLSTYGLERKTLSHS
IVLDDEESELKPQNANPRGAHDSEDEHDLLDEIINTFNQRWFHGWNVTPEDQRVKFVTLSKHVQAHPDFETKVANNKDIQ
NREIAFQKILEEVMMQQRKKELDLYKLYTQDDSFRQAFFDTMKQMMGNSSSSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 65
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 65
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fleli_0174 YP_006432466.1 helicase, type I site-specific restriction-modification system restriction subunit VFG1098 Protein 0.0 65