Gene Information

Name : Desde_3522 (Desde_3522)
Accession : YP_006431597.1
Strain : Desulfitobacterium dehalogenans ATCC 51507
Genome accession: NC_018017
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.15
Position : 3524845 - 3526146 bp
Length : 1302 bp
Strand : -
Note : PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGACCGATTGGAATAATCTGCTTCATAGAATAGATGATTTGGATTTGATCGTCTCTCATGGCCGGGTGGCCAAAATCGT
GGGGCTGATGATTGAATCCGACGGTCCTCGTGTCAGTGTGGGAGAATACTGTAAGATCCATACCCGGCAGGGAAAAGAAA
TTCCGGCTGAGGTGGTGGGCTTTCGCAATTCCACCACCCTGCTGATGCCTCTAGCTGAATTAGAAGGAATCGCTCCGGGG
GATCGGGTGGTTCCTCAACAACATAAGCTGGAAGTCGGAGTCGGGCAGGCCCTTCTGGGTAGAATTCTCGATGGACTGGG
CCGGCCCTTGGATGGGCGTCCTATGGTTACTCATAAGGATTATCCATTGCAAAATTCTCCTCCCAGTGCTTTTCTAAGAC
CAAGAATTCGCGACCCTCTCAGTGTGGGGGTTCGCACGGTGGATGGGATGCTAACCATTGGCCGGGGACAGAGAATTGGG
ATTTTCGCTGGTTCAGGAGTGGGTAAAAGTACCCTGCTGGGAATGATGGCAAGGAATACCACAGCCGATGTGAATGTCAT
TGCTCTGGTTGGAGAACGGGGAAGAGAACTTCGGGACTTTATCGAGAAGGATCTCGGCGAAGAGGGCTTAGAGCGTTCCG
TACTCGTGGTAGCAACCTCTGACCAACCCGCCTTGGTTCGCCTCAAGGCTGCTTTCACAGCCACGGCCATCGCCGAATAC
TTCCGGGACCAAGGCCAGGATGTACTCTTAATGATGGATTCCGTGACCCGCTTTGCCATGGCTCAACGGGAAGTGGGGTT
GACCACCGGGGAACCGCCGGCAACCCGTGGCTATCCGCCTTCAGTATTTGCTTTGCTGCCCAAACTTCTTGAGCGCTCCG
GCATGAGCGAGGTCGGAAGCATTACAGGGATTTACACAGTCCTTGTGGATGGGGACGATCATAACGAACCTATCGCCGAC
ACAGTCCGTGGAATCCTGGACGGACATATCGTCCTAACCCGGGAATTAGCCATGCAGAACCATTATCCGGCCATTGATAC
GCTCCAATCCGTAAGCCGGGTCATGAATGATATTATCTCACCGGAACATAAAGAGCTGGCCGGAAAACTCCGGGAGCATC
TTGCTATCTATCATGATGCTAAGGATTTAATTGACATCGGAGCCTATGTGGCAGGAAGCAACCCCCGTATCGATGCCGCA
ATCCAGCATATAGAAGGAATCAATGGTTTCCTCCGTCAGGACGTGGAGGAGAAAGTCTCCTTCGACGAAATGATCCAGCA
ACTTCATCAGGCCCTTATGTAA

Protein sequence :
MTDWNNLLHRIDDLDLIVSHGRVAKIVGLMIESDGPRVSVGEYCKIHTRQGKEIPAEVVGFRNSTTLLMPLAELEGIAPG
DRVVPQQHKLEVGVGQALLGRILDGLGRPLDGRPMVTHKDYPLQNSPPSAFLRPRIRDPLSVGVRTVDGMLTIGRGQRIG
IFAGSGVGKSTLLGMMARNTTADVNVIALVGERGRELRDFIEKDLGEEGLERSVLVVATSDQPALVRLKAAFTATAIAEY
FRDQGQDVLLMMDSVTRFAMAQREVGLTTGEPPATRGYPPSVFALLPKLLERSGMSEVGSITGIYTVLVDGDDHNEPIAD
TVRGILDGHIVLTRELAMQNHYPAIDTLQSVSRVMNDIISPEHKELAGKLREHLAIYHDAKDLIDIGAYVAGSNPRIDAA
IQHIEGINGFLRQDVEEKVSFDEMIQQLHQALM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-108 54
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-105 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-106 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-105 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-106 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-104 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-107 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-104 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-106 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-106 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-92 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-96 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-95 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-95 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-95 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-95 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-91 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-91 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-93 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-93 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-92 48
escN AAL57542.1 EscN Virulence LEE Protein 1e-92 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-92 48
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-93 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-92 48
escN AAC38383.1 EscN Virulence LEE Protein 7e-93 48
escN AAC31513.1 L0034 Virulence LEE Protein 1e-92 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-92 48
escN AAK26715.1 EscN Virulence LEE Protein 1e-92 48
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-91 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-93 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-84 47
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-81 47
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-81 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-88 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-87 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-88 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-91 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-80 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-94 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-86 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-87 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-87 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-77 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-74 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-73 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-73 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-73 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-73 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 5e-113 54
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 6e-108 54
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 9e-112 54
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 5e-106 54
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 3e-103 51
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 8e-96 50
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 7e-93 49
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 7e-93 48
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 4e-93 48
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-94 47
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 2e-73 42
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 3e-73 42
Desde_3522 YP_006431597.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 2e-82 41