Gene Information

Name : Alfi_0581 (Alfi_0581)
Accession : YP_006409653.1
Strain : Alistipes finegoldii DSM 17242
Genome accession: NC_018011
Putative virulence/resistance : Unknown
Product : type I restriction system adenine methylase HsdM
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 651850 - 653403 bp
Length : 1554 bp
Strand : -
Note : PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM)

DNA sequence :
ATGAGTGAAGAACTGCAACAGAAACTCCGTGACCAGCTTTGGGCGGTCGCAAACCGTTTGCGCGGCAATATGTCGGCAAG
CGATTTTATGTATTTTACTTTGGGATTCATTTTCTATAAATACCTGTCGGAGAAGATAGAAACATACGCCAACAGTGCAT
TGGAGGATGATGAAGTTACATTCAAGGAATTATGGGAAATGACCGATTCGGATGCTGCGGAATTGCAGGAAGAGGTCAAG
AACCAATGCTTGGAAAATATAGGCTATTTCATTGAACCGAAATTCTTGTTTTCGTCTGTAATCGAAACTATCAAGCGGAA
AGAAAATATCCTTCCGATGCTGGAACGCTCATTGAAACGCATTGAGGATAGTACGCTCGGACGTGACAGCGAAGAGGATT
TTGGTGGTCTGTTTTCGGATATTGACCTTGCTTCCCCTAAGCTCGGAAAGACAACCGATGACAAGAATACGCTTATAAGC
AATGTTCTGCTTGCACTTGATGATATAAAATTCGGAGTGGAGGCCTCTCAGGAGATTGATATTTTGGGCGATGCTTATGA
GTATATGATCAGTCAGTTTGCTGCCGGTGCAGGCAAGAAAGCCGGTGAGTTCTATACTCCGCAAGAGGTCAGCCGCATAT
TGGCGGAGATTGTTACTCTTGGGCATAACCGTTTGCGTAATGTTTACGACCCTACTTGCGGTAGTGGTTCACTATTGCTC
CGTGCAGCAAGTATCGGTAAGGCGGCATATATCTATGGACAGGAGAAAAATCCGACTACTTACAACCTTGCCCGAATGAA
TATGTTGCTGCACGGTATCCGATTCAGCAGCTTCAAAATAGAGAATGGCGATACGCTTGAATGGGACGCATTCGATGATA
TGCAGTTCGATGCAGTGGTTGCAAATCCTCCGTTCTCTGCCGAATGGAGTGCTGCCGACAAATTCAACAACGACGACCGT
TTCAGTAAAGCAGGACGACTTGCACCTAAGAAAACAGCCGACTATGCTTTTATTCTGCATATGGTTCATCACCTCAATGA
AGGTGGTACGATGGCTTGCGTTGCTCCGCACGGAGTTCTGTTCCGAGGGAATGCAGAGGGCGTTATACGCCGTTTCCTGA
TAGAGAAGAAAAACTATATTGATGCCATTATCGGGCTGCCTGCCAATATTTTCTATGGTACAAGCATTCCGACCTGTATT
CTCGTATTGAAGAAATGCCGTAAGGAAGACGATAATATCTTGTTCATTGATGCCAGCAAAGAGTTTGAAAAGGTCAAGAC
CCAAAACAAACTCCGCCCTCAGCATATACAGAAGATTGTAGAAACCTACCGTGACCGCAAGGAAATTGAAAAGTACAGTC
ACCTCGCTACGTTACAGGAGGTTGCCGAAAATGACTATAATCTGAATATTCCTCGTTATGTCGATACTTTTGAGGAAGAA
GAGCCTATTGACATCAAAGCAGTCATGGCTGAAATAAAGGAATTGGAAGCCAAGCGAGCCGAACTGGATAAGGAGATAGA
AGGCTATTTGAAAGAATTGGGACTGGTTGAATAA

Protein sequence :
MSEELQQKLRDQLWAVANRLRGNMSASDFMYFTLGFIFYKYLSEKIETYANSALEDDEVTFKELWEMTDSDAAELQEEVK
NQCLENIGYFIEPKFLFSSVIETIKRKENILPMLERSLKRIEDSTLGRDSEEDFGGLFSDIDLASPKLGKTTDDKNTLIS
NVLLALDDIKFGVEASQEIDILGDAYEYMISQFAAGAGKKAGEFYTPQEVSRILAEIVTLGHNRLRNVYDPTCGSGSLLL
RAASIGKAAYIYGQEKNPTTYNLARMNMLLHGIRFSSFKIENGDTLEWDAFDDMQFDAVVANPPFSAEWSAADKFNNDDR
FSKAGRLAPKKTADYAFILHMVHHLNEGGTMACVAPHGVLFRGNAEGVIRRFLIEKKNYIDAIIGLPANIFYGTSIPTCI
LVLKKCRKEDDNILFIDASKEFEKVKTQNKLRPQHIQKIVETYRDRKEIEKYSHLATLQEVAENDYNLNIPRYVDTFEEE
EPIDIKAVMAEIKELEAKRAELDKEIEGYLKELGLVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 1e-150 60
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 7e-146 58
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 7e-146 58
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 7e-146 58
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 9e-146 58
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 7e-146 58
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 9e-146 58
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 9e-146 58
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 8e-146 58
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 8e-146 58
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 1e-145 58
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 3e-144 58
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 8e-145 58
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 4e-146 58
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 8e-145 58
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 2e-146 58
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 6e-145 58
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 2e-145 58
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 8e-146 58
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 1e-145 58
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 1e-145 58
ORF6 BAC22943.1 - Not tested etd PI Protein 3e-145 57