Gene Information

Name : Alfi_1061 (Alfi_1061)
Accession : YP_006410101.1
Strain : Alistipes finegoldii DSM 17242
Genome accession: NC_018011
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1129195 - 1130913 bp
Length : 1719 bp
Strand : -
Note : PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit

DNA sequence :
ATGGCAACAATTTCACGTCAAGAATACAACAACCTTTTCGGTCCTACCGTCGGCGACAAGATCCGGCTGGGTGACACCGA
TCTTTACGTCGAGATCGAAAAAGACCTGCGCGAATACGGCGACGAGGTCGTCTACGGCGGCGGCAAGACCATCCGCGACG
GCATGGGGCTGGCCAATACGATGACTTCGGAGGAGGGGGCGCTCGACCTCGTGATTACCAACGTGACGATCATCGACGCC
AATCTGGGCGTCGTGAAGGCCGACGTGGGTGTCAAGGACGGAAAAATCGCCGGTATCGGCAAGGCGGGAAATCCCAATAT
CATGCACGGCGTGCATCCCGATCTGGTGACCAGCACCGCAACCGACGCGATATCGGGCGAGCACCTGATCCTGACGGCAG
CCGGCATCGACGGCCACGTGCACATGATCTCCCCGCAGCAGGCTTACGCCTGTCTGAGCAACGGTATTACGACCCTGTTC
GGCGGCGGAATCGGCCCTACGGACGGCAGTAACGGAACCACCATCACTTCAGGCCGCTGGAACATCGAACGCATGCTGGA
GTCGATCGAGGGGCTTCCGGTGAACGTCGGCCTGCTGGGCAAGGGCAACTGCTCGATGAACCAGCCGCTCGAAGAACAGA
TCGAGGCCGGAGCCTGCGGCCTGAAGATTCACGAGGACTGGGGCTCGACTCCCGCTGCGATCCGCGCCGCGCTGGGCGTC
GCCGATCGTTTCGACGTGCAGGTGGCCATCCACTCCGATACGCTCAACGAGAGCGGATACGTCGAGGATACGATCGCCGC
CATGGACGGCCGCACGATCCATACCTACCACACCGAAGGCGCCGGCGGCGGACACGCCCCCGACCTGCTGAAAGTGGCGT
CGATGCCCTACGTGCTGCCTTCGTCGACCAATCCGACCCTGCCGTTCGGGGTCAATTCCCAAGCCGAGCTGTTCGACATG
ATCATGGTCTGCCACAACCTAAATCCGAAGATCCCGTCGGACGTGGCCTTTGCCGAGAGCCGCGTGCGGCCCGAAACGCA
GGCCGCGGAGAACGTGCTGCACGATCTGGGCATACTGTCGATGGTTTCGTCCGACTCGCAGGCCATGGGCCGTATCGGCG
AATCGTTCATGCGCACGTTCCAGATGGCGTCGTTCATGAAGAACGCCTGCGGCAAGCTCGCCGAGGATGCCGACGGGAAC
GACAACTTCCGCGTGCTGCGCTATATCGCCAAGATCACGATCAACCCGGCCATCACCTACGGCGTTTCCGACTACCTCGG
ATCGGTCGAGAAGGGCAAGGTCGCCGACCTCGTACTCTGGGAGCCGCAGTTCTTCGGCGCCAAACCCAAGATGGTCATCA
AGGGCGGCCTGATCAACTGGTCGAACATGGGCGATCCCAACGCATCGCTCCCGACGCCGCAGCCGTGCTATTACCGTCCG
ATGTACGGCGCTTTCGGCCGTACGCTGCCCGAAACCTGCCTTTCGTTCGTATCGGGCGCCGCGTTCCAGAGCGGTATCAA
GGAGCGTCTCCACCTGCATCGTATGGTGCAGCCCGTGCGGCGCACCCGCCAGCTTACCAAATACAACATGGTGCGCAACG
GAGGAATGCCGAAGATCGACGTGAATCCCGAAACGTTCGACGTGCTGGTCAACGACATCCGCGCTTACGTCAAGCCTGCC
GACAAATTCCCCCTGAGCCAGCTGCTCTGGTTCAGTTAG

Protein sequence :
MATISRQEYNNLFGPTVGDKIRLGDTDLYVEIEKDLREYGDEVVYGGGKTIRDGMGLANTMTSEEGALDLVITNVTIIDA
NLGVVKADVGVKDGKIAGIGKAGNPNIMHGVHPDLVTSTATDAISGEHLILTAAGIDGHVHMISPQQAYACLSNGITTLF
GGGIGPTDGSNGTTITSGRWNIERMLESIEGLPVNVGLLGKGNCSMNQPLEEQIEAGACGLKIHEDWGSTPAAIRAALGV
ADRFDVQVAIHSDTLNESGYVEDTIAAMDGRTIHTYHTEGAGGGHAPDLLKVASMPYVLPSSTNPTLPFGVNSQAELFDM
IMVCHNLNPKIPSDVAFAESRVRPETQAAENVLHDLGILSMVSSDSQAMGRIGESFMRTFQMASFMKNACGKLAEDADGN
DNFRVLRYIAKITINPAITYGVSDYLGSVEKGKVADLVLWEPQFFGAKPKMVIKGGLINWSNMGDPNASLPTPQPCYYRP
MYGAFGRTLPETCLSFVSGAAFQSGIKERLHLHRMVQPVRRTRQLTKYNMVRNGGMPKIDVNPETFDVLVNDIRAYVKPA
DKFPLSQLLWFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-135 57
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-135 57
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-129 55
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-129 55
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-129 55
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-129 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alfi_1061 YP_006410101.1 urease subunit alpha VFG0270 Protein 2e-145 58