Gene Information

Name : Desfe_0454 (Desfe_0454)
Accession : YP_006401934.1
Strain : Desulfurococcus fermentans DSM 16532
Genome accession: NC_018001
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 430082 - 431653 bp
Length : 1572 bp
Strand : +
Note : PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0519 GMP

DNA sequence :
ATGACGCGAGAGAACATTACCAATATACCTGGAAGCAGGATCCTGATAGTGGACTACGGTGGGCAGTACACACATTTAAT
AGCTAGGAGAATCAGGGAACTCGAAGTATACTCCGAGATAGTCTTCTATAGGGATTTAAATCGCGTTAACATCGAGGACT
ATGACGCGGTAATATTATCAGGCAGTCATTTAAGCGTGAAAAGCCTTGACAAAGACGCCGTGGAGACAGCTAGGAAGATC
CTCATGGAGGGAGATAAGCCATTACTAGGAATATGCTTCGGCCACCAGTTAATAGGATACCTCCTCGGCGCCAAGCTGTC
TACAGGGTGCAGCGAGTATGGTAGAACCACCATGAAGATACTGAGTAGTGATGAATTGTTTAATGGATGGGGCAACAGCG
AGGTAGTCTGGATGAGCCACGGTGAATGCATCGAAGACCTCCCCGACTCCATTACATTACTGGCTGAAAGCGAGAATAAA
GTGGTGGCAGCTATTAAAGCAGTCGTGAACAACAGGGCTGTCTACGGTGTCCAATTTCATCCAGAGGTACATCACACTGT
GAAAGGCCGGAGGCTCCTGGATAACTTCCTCGGGATCATTAATGCGAAAAAGGCTTGGAGGACCGAGAACTACTATAGGT
ACATAATTGATGAACTCGGCAGGGAGGTAACCAGGAATGGTGTAGCCGTTGTCGGTGTCAGCGGCGGCATAGATTCAACT
GTTACAGCCTTGATAGGGAAGAAGCTCTTCGGCGATAAATTAATATCCGTGTTCGTTGACCATGGTTTACTAAGGGAGGG
GGAAAGAGAGCTTGTTGTCTCATCCCTCGAGAAACTCGGGTTAAACCCCTTAATAGTGGATGCCGGAGAGAGATTCATCT
CGAAGCTCGAGGGCTCCACTGACTGCGAGGAGAGGCGTAGAGTAATAGGTGAGGAGTTTGCGAGAATATTCTCTGAAATC
ATTGAAAAAGAAGGTGCCGAATACTTCCTACAGGGTACAACATACCCTGATATAATCGAGAGTGGTGGAACCCGTAAGGC
AGCCTCAGTGATCAAATCACACCATAACGTCGGAGGATTACCCGAGTGGTTTAGGGGTAGGGTTAAGATATTGGAGCCGC
TGCGTTTCCTCTACAAGGATGAGGTGAGAGAGATAGCTAGGTTACTCGGCGTTCCCCGTGAAATAATCGAGAGACATCCG
TTTCCGGGACCTGGGTTAGCTGTCAGGATTACAGGTATCTTCACAAAGAAGAAGCTGGATGTGTGCAGGAGGGCCTCTAA
GATAGTTGAGGACGTGCTCGGAGAGTACGGGTTATACAGTAGAGTGTGGCAGGCCTTCGCTGTTGTAGGCGATGATAGAT
GGGTCGGGGTAAAGGGTGATGCTAGAAGCCACGGCTACATAGTCACCGTTAGAATAGTCGAAAGCGTTGACGGGATGACT
GCCGACTACTCAAAGATACCCTATGATGTACTCGATGAGATTAGTAGGAGGATCACTAATAGTATCCAGGATGTGACAAT
GGTTACCTACGCTATCACATCCAAGCCCCCCAGCACTATAGAGCCCTGCTGA

Protein sequence :
MTRENITNIPGSRILIVDYGGQYTHLIARRIRELEVYSEIVFYRDLNRVNIEDYDAVILSGSHLSVKSLDKDAVETARKI
LMEGDKPLLGICFGHQLIGYLLGAKLSTGCSEYGRTTMKILSSDELFNGWGNSEVVWMSHGECIEDLPDSITLLAESENK
VVAAIKAVVNNRAVYGVQFHPEVHHTVKGRRLLDNFLGIINAKKAWRTENYYRYIIDELGREVTRNGVAVVGVSGGIDST
VTALIGKKLFGDKLISVFVDHGLLREGERELVVSSLEKLGLNPLIVDAGERFISKLEGSTDCEERRRVIGEEFARIFSEI
IEKEGAEYFLQGTTYPDIIESGGTRKAASVIKSHHNVGGLPEWFRGRVKILEPLRFLYKDEVREIARLLGVPREIIERHP
FPGPGLAVRITGIFTKKKLDVCRRASKIVEDVLGEYGLYSRVWQAFAVVGDDRWVGVKGDARSHGYIVTVRIVESVDGMT
ADYSKIPYDVLDEISRRITNSIQDVTMVTYAITSKPPSTIEPC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-84 42
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-83 42
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-84 42
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-85 42