Gene Information

Name : pyk (BBB_0742)
Accession : YP_006394215.1
Strain : Bifidobacterium bifidum BGN4
Genome accession: NC_017999
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 902117 - 903559 bp
Length : 1443 bp
Strand : +
Note : COG0469:Pyruvate kinase

DNA sequence :
ATGCGTAAAGCCAAGATCGTAGACACCATCGGTCCTTCCACCGAGTCTCCCGAAGGCATCACCAAGCTGGTTGAGGCCGG
TATGGACGTGGCCCGTCTGAACCGTTCCCACGGCACTCCGGAGGATCACCTCAAGGTCTACAACAACGTGCGCGCGGCCT
CCAAGGCGACCGGTCGTAACGTCGCCGCCATGGTCGATCTCCAGGGCCCGAAGATCCGCTGCGGCTGGTTCAAGAAGAAC
GCCGAGGGCGAGGACAAGGTCCAGCTTGAGGAAGGCCAGGAGTTCATCATCACCACCGACGATGTCGAAGGCGACGAGCA
CATCACCTCCACCACCTTCAAGGGCCTGCCCGGCGACTGCCACCCCGGCGACCCGATCCTGATCGACGACGGCAAGGTTC
GTCTGGAGGTCACCAAGGTCGAGGGCAACAACGTGCACACCAAGGTCGTCGTTGCCGGCCCGGTCTCCTCCCACAAGGGC
ATCAACCTGCCCGGCGTGGCCGTGAGCCTGCCCGCCCTGACCGAGAAGGATGAGGCCGATCTGCGTTGGGCCATCCGCAC
CGGCGCCGACATCATCGCCATGTCCTTCGTGCGTTTCGCCACCGACATCGACCGCGCCCACGAGATCATGGACGAGGAAG
GCCGTCGTATCCCGATCGTCGCCAAGATCGAGAAGCCGCAGGCTCTGGAGAACCTTGAGGACATCGTCAAGACGTTCGAC
GGTGTCATGGCCGCCCGTGGCGACATGGCCGTCGAGTGCCCGCTGGAAGAGGTCCCGCTGGCCACCAAGCGCATCATCGA
GCTGGCTCGTCAGTACGCCAAGCCCGTCATCGTCGCCACCGAGGTCCTGGGCTCCATGGTCCACTCCCCGGTTCCGTCCC
GTGCAGAGGCTTCCGACTGCGCCAACGCCGTGCTTGACGGTGCCGACGCCACGATGACCTCCAACGAGACCGCCGTCGGC
GAGTACCCGACCGAGACCGTCGCCACGATGAGCCGCATTTCCGGCTTCGCCACCGAGCACGGCTTCGACCGCATCCCCGA
GCTGAAGAACCTCGACATGTCCTCCACCGGCGCCGTTTCCTCCGCCGCCGTCGACCTGGCCGAGAAGCTCAACGCCAAGG
CCATCGTCGCTTACACCCAGACCGGCAACACCGTGCACCGTGTGTCCCGCGAGCGTCCGGCCGCCCCGATCTACGGCCTG
ACCACCAACGAGCACACCTACCACTGGCTGGCCCTCTCCTGGGGCACCGAGGCCTTCCTGCTCGATGAGGACTACCACGA
CAAGACCCGCAAGGATCTCATGGCCTTCACCGACAAGGTCCTCAAGAACGCCGGCAAGGTCTCCGACGGCGACAAGATCG
TCGTGCTGAGCTCCGCTCAGGGCGAGCACGCCGCTGGCAGCACCGACACCATCTACGTGCACACCGTCGGTGCCAACGAC
TGA

Protein sequence :
MRKAKIVDTIGPSTESPEGITKLVEAGMDVARLNRSHGTPEDHLKVYNNVRAASKATGRNVAAMVDLQGPKIRCGWFKKN
AEGEDKVQLEEGQEFIITTDDVEGDEHITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVHTKVVVAGPVSSHKG
INLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEGRRIPIVAKIEKPQALENLEDIVKTFD
GVMAARGDMAVECPLEEVPLATKRIIELARQYAKPVIVATEVLGSMVHSPVPSRAEASDCANAVLDGADATMTSNETAVG
EYPTETVATMSRISGFATEHGFDRIPELKNLDMSSTGAVSSAAVDLAEKLNAKAIVAYTQTGNTVHRVSRERPAAPIYGL
TTNEHTYHWLALSWGTEAFLLDEDYHDKTRKDLMAFTDKVLKNAGKVSDGDKIVVLSSAQGEHAAGSTDTIYVHTVGAND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-65 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-64 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-65 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006394215.1 pyruvate kinase VFG0479 Protein 2e-65 41