Gene Information

Name : clpA (BBB_0642)
Accession : YP_006394115.1
Strain : Bifidobacterium bifidum BGN4
Genome accession: NC_017999
Putative virulence/resistance : Virulence
Product : putative ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 783246 - 785822 bp
Length : 2577 bp
Strand : +
Note : COG0542:ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAACGGTTTACCGACCGTGCACGGCGCGTGATCGTGTTGGCGCAGGAAGAGGCGCGTACTCTCCAGCACAACTA
CATCGGCACCGAACACCTGCTGCTCGGCCTGATCCGCGAAGGTGAGGGGGTCGCCGCCAAGGCGCTCGCATCCAAGGGAG
TGACCTTGGACGACACCCGCAAGCAGGTCGAGGAGATGATCGGCAAAGGCAATGCCGCCCCCAACGGGCACATTCCCTTT
ACTCCGCACGCCAAGCAGGTGTTGGAGCTGAGTCTGCGCGAGGCGCTGCAGCTCGGTCACAGCTATATCGGCACCGAGCA
CATCCTGCTCGGCCTGATTCGCGAAGGTGAGGGCGTGGGCACCCAGGTGCTCATCAAGATGGATGTCGACCTGGGCGAAC
TGCGTTCGGCCACTATCGACATGATCCATGGCAACAGCGGCGGCGCCAATGCCTCCGGCAAGGGCGATCTGGCCAACGCC
GGTGGCGTGCAGGACAAGCGCAGCCAGACCGGTTCGGCCATTCTGGACCAGTTCGGGCGCAACCTGACCGCCGAAGCGGC
CGAGGGCAAGCTCGACCCGGTGATCGGGCGCACCAACGAGATCGAACGTGTCATGGTCGTGCTGTCGCGCCGCACGAAGA
ACAACCCCGTGCTGATCGGCGAGCCGGGCGTCGGCAAGACCGCCGTCGTCGAAGGCCTCGCGCAGAAGATCAACGCCGGC
GACGTGCCGGAGACGCTGAAGGACAAGCAGGTCTATTCGCTGGATCTGGGCTCCATGGTGGCCGGCTCGCGCTACCGCGG
CGATTTCGAGGAACGCCTCAAGAAGGTGCTCAAGGAGATCAAGACGCGCGGCGACATCGTGCTGTTCATCGACGAGATTC
ACACGATCGTCGGTGCCGGTTCGGCGGACGGCGCCTTGGGCGCGTCTGACATGCTCAAGCCCATGCTGGCTCGCGGTGAG
CTCCAGACCATCGGCGCCACCACCACCGACGAGTACCGCAAGTACATCGAGAAGGACGCGGCGCTGGAACGTCGTTTCCA
GCCGATTCAGGTGCATGAGCCGACAATCGCGGAGACCATCGAAATCCTCAAGGGCCTGCGCTCGCGCTACGAGAACCACC
ACCACGTGACCATCACCGACGGTGCGCTGCAGTCCGCCGCGGAGCTGTCGTCCCGCTACATCCAGGACCGCAACCTGCCC
GACAAGGCCATCGACCTGATCGACGAGGCCGGCGCGCGGCTGCGCATCAAGCGCCTGACCGCCCCGCCCGAGCTCAAGGA
ACTTGACCAGAAGGTCGCGAAGGTCGCCGCCGAGAAGGACAAGGCCATCAAGGACCAGGACTTCGAGAAGGCCGCCGAGC
TGCGCGACAACCAGGAGAAGCTGGAAGCGGAGCGCAAGGAGAAGGAATCCTCCTGGCGCGAGGGCGAGTCCGATGTCGAG
ATGGTCGTGAACGAGGATGTGATCGCCCAGGTGATCTCCTCGACCACCGGCATTCCGGTGTTCAAGCTCACCCAGGCCGA
GTCGAAGAAGCTGCTCGGCATGGAGTCCGAGCTGCACAAGCGCATCATCGGCCAGGACGAAGCGGTTTCCGCGCTGTCCC
GTTCGATTCGCCGCACTCGTGTGGGCCTCAAGGATCCGAAGCGTCCTGCGGGCTCGTTCATCTTCGCCGGCCCGACCGGC
GTCGGCAAGACCGAGCTGGCCAAGGCGCTGGCCGAGTTCCTGTTCGACGATGAGGACGCGCTGATTCGCGTGGACATGTC
GGAGTTCTCCGAGAAGTATGCGGCATCGCGTCTGTTCGGTGCTCCTCCGGGATACGTCGGTTATGAGGAGGGTGGCGAGC
TCACCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTCGTGCTGTTCGACGAGATCGAGAAGGCCCATCCGGACATCTTCAAC
ACGCTGCTGCAGGTGCTGGACGACGGTCACCTGACCGATGGTCAGGGACGCAAGGTGGACTTCAAAAACACCATCATCAT
CCTGACCACCAACCTGGGTACGCGCGACATCTCCAAGGCCGCCAACACCGGCTTCAACCTTGGCTCGAACGCGGAGTCCA
GCTACCAGCGCATGAAGGATCAGGTCAGCTCCGAACTCAAGCAGCAGTTCCGCCCCGAGTTCCTGAACCGTCTTGACGAC
ATCATCGTGTTCCGTCAGCTCACCGAGCCGCAGGTGCGTCAGATTGTCGACCTCGACATCAAGCAGCTCAACGACCGTCT
GTTCGACCGTCACATGTCGCTGGAGCTCACCCCGGCCGCCAAGGACCTGCTCGCGCAGAAGGGCTTCGACCCGCTGCTCG
GTGCTCGTCCGCTGCGCCGCGTGATCCAGCGCGACATCGAGGACGCCATCTCGGAGAAGATCCTGATGGGCGAACTCGAG
GACGGTCAGCGCGTGGTGGTCGACTCCGAAGGCGAGGGCATCCTCGGCGAGTTCACCTTCCGCGGCGAACAGTTCGACGA
CGCCAAGCCCGAGAACGAGCCGGCTGCGGAGCCGGCAACGGAGGAGTCAGCTGACAAGTCGTCTGACAACGCCGCTCCCG
CCTCGCAGGAGGCCTGA

Protein sequence :
MFERFTDRARRVIVLAQEEARTLQHNYIGTEHLLLGLIREGEGVAAKALASKGVTLDDTRKQVEEMIGKGNAAPNGHIPF
TPHAKQVLELSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMDVDLGELRSATIDMIHGNSGGANASGKGDLANA
GGVQDKRSQTGSAILDQFGRNLTAEAAEGKLDPVIGRTNEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKINAG
DVPETLKDKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGE
LQTIGATTTDEYRKYIEKDAALERRFQPIQVHEPTIAETIEILKGLRSRYENHHHVTITDGALQSAAELSSRYIQDRNLP
DKAIDLIDEAGARLRIKRLTAPPELKELDQKVAKVAAEKDKAIKDQDFEKAAELRDNQEKLEAERKEKESSWREGESDVE
MVVNEDVIAQVISSTTGIPVFKLTQAESKKLLGMESELHKRIIGQDEAVSALSRSIRRTRVGLKDPKRPAGSFIFAGPTG
VGKTELAKALAEFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFN
TLLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDISKAANTGFNLGSNAESSYQRMKDQVSSELKQQFRPEFLNRLDD
IIVFRQLTEPQVRQIVDLDIKQLNDRLFDRHMSLELTPAAKDLLAQKGFDPLLGARPLRRVIQRDIEDAISEKILMGELE
DGQRVVVDSEGEGILGEFTFRGEQFDDAKPENEPAAEPATEESADKSSDNAAPASQEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_006394115.1 putative ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 57
clpA YP_006394115.1 putative ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 2e-136 50