Gene Information

Name : clpB (BBB_0270)
Accession : YP_006393745.1
Strain : Bifidobacterium bifidum BGN4
Genome accession: NC_017999
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 332307 - 334970 bp
Length : 2664 bp
Strand : +
Note : COG0542:ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGAACAGAAGTTCACCACCATGGCCCAGGAAGTCATCGGTGATGCGATTCAGAGCGCGTCTGCCGCGGGCAACGCGCA
GGTCGAGACACTGCACGTGATGGATGCGCTGCTGCGTCAGGAAAACGGCGTGATTCAGGGGCTGATTCAGGCGGCGGGCG
GCAGCCCGCAGGCGATTGGCGCCGCGGTGCGCAATGCTCTGGTCAAGATGCCGGCGGCGAGCGGGTCCACCACATCGCAG
CCGCAGGCGAGCCGCCAGCTGACGGCGGCGCTGGCACAGGCCGAGAAGGAGATGCAGCAGATGGGCGACGAGTACGTCTC
CACCGAGCACCTGCTCATCGGCATCGCCGCATCCGCACCGAACCAGAGCGCGGACATCCTCAAAGCGAACGGCGTGACGG
CCGCGGCGCTGCGCAAGGCCGTCCCCGGCGTGCGCGGCGGCGCCAAGGTCACCAGCCCGGACGCTGAGGGCAGCTACAAG
GCGTTGGAGAAGTACTCCACCGATCTGACCGCCCGCGCCAAGGAGGGTAAGCTCGACCCGGTGATCGGGCGTGATCAGGA
GATCCGCCGTGTGATCCAGATCCTGAGCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCGTCGTGGAGGGCCTCGCCCAGCGTATCGTGGCCGGCGATGTGCCGACCACGCTGCAGAACAAGAAGCTCATCAGC
CTCGATTTGGGGTCGATGGTTGCCGGCTCGAAGTACCGTGGCGAGTTCGAGGAGCGCCTCAAGAGCGTGCTCAACGAAAT
CAAGAACGCCGACGGCCAGATCATCACGTTCATCGACGAGATTCATACGATCGTCGGCGCTGGCGCGGCCGAAGGCTCGA
TGGATGCCGGCAACATGCTCAAGCCCATGCTGGCGCGCGGTGAGCTTCGCCTGATCGGCGCGACCACGCTGGACGAGTAC
CGTGAGAACATCGAGAAGGACCCGGCGCTTGAGCGTCGTTTCCAGCAGGTGTTCGTGGGCGAGCCGAGCGTGGAGGACAC
GATCGCGATTCTGCGTGGCCTGAAGCAGCGTTACGAGGCGCACCACAAGGTGACGATCGGCGACGACGCGCTGGTCGCCG
CCGCGACGCTCTCGAACCGCTATATTTCCGGCCGTCAGCTGCCCGACAAGGCCATCGATCTGGTCGATGAGGCGGCCGCG
CACCTGCGCATGGAGCTCGACTCCTCCCCGGAGGAGATCGACGAACTGCAGCGCAAGGTCACGCGCTACGAGATGGAGGA
GATGCAGCTCAAGAAGGCCGAGGATCCGGCCAGCAAGGAGCGCTTGGAGAAGCTGCAGAACGAGCTCGCGAACACTCGCG
AGAAGCTGAGCGGCCTCAAGGCCCGCTGGGATGCGGAGAAGGCCGGCCACAACAAGGTCGGCGACCTGCGCGCCCAGCTG
GACGCCAAGCGCGTCGAGGCTGACAAGTTCACCCGTGAGGGCAACCTGGCCGAGGCGTCGAAGATCCTGTACGGCGAGAT
TCCGGCGATTCAGAAGCAGCTGGACGCGGCCGAGAAGGCCGATGCGGAAGACGGCGCGACGGGCGAGACCAAGCCCGAGC
CGATGGTGCCCGACCATGTGGACGCCGATTCGGTGGCCGGCATCGTCTCCGAGTGGACCGGCATCCCCGTCGGTCGCCTG
ATGCAGGGCGAGAACGAGAAGCTGCTGAGCATGGAGGACTATCTCGGCAAGCGCGTGATCGGCCAGAAGGAAGCGATCGC
GGCGGTGAGCGACGCGGTGCGTCGTTCGCGCGCCGGCATCAGCGACCCGAACCGTCCGACCGGCTCGTTCCTGTTCCTCG
GCCCCACCGGCGTGGGCAAGACCGAGCTCGCCAAGGCGCTCGCCGACTTCCTGTTCGACGACGAGAAGGCCATGGTCCGC
ATCGATATGTCGGAGTACATGGAGAAGGCGTCTGTGAGCCGTCTGATCGGCGCCGCGCCCGGCTACATCGGCTATGAGGA
AGGCGGCCAGCTGACCGAGGCCGTGCGTCGTCGTCCGTACTCGGTGGTGCTGTTCGACGAAGTCGAGAAAGCTAACCCCG
AAGTCTTCGACGTGCTGCTGCAGGTGCTGGACGACGGGCGTCTGACCGACGGCCAAGGCCGGACTGTGGACTTCAAGAAC
ACGATCCTGATCATGACCTCGAACCTCGGCTCGCAGTTCCTGGTGAACCAGGACATGGACGCGGATGCCAAGAAGAAGGC
CGTGATGGACGCGGTGCACATGAACTTCAAGCCGGAGTTCCTGAACCGTCTGGACGAGATCGTGATGTTCCATCCGCTGA
CCCGTGAGGAGCTGGGCGGCATCGTCAGCATCCAGGTCGCTCAGGTGGCCTCGCGTCTGACGGATCGCCGCATCAAGCTC
GACGTCACCGACGCGGCTCGCGAATGGCTCGCCAACACCGGCTATGACCCGGCGTACGGCGCTCGTCCGCTGCGCCGTCT
GGTGCAGACCGAGGTCGGCGACCAGCTGGCGCGCATGCTGCTCGCCGGCAAGGTACACGACGGCGACACCGTGCTCGTCA
ACCAGACCGGTGGCGAGCATCTGGAACTCGGTACCATGCCCGAGGATCCGGATGCCGGCTCCGATACCGACGTCACGGTC
GAAGACGTCACCGAAGACAAATGA

Protein sequence :
MEQKFTTMAQEVIGDAIQSASAAGNAQVETLHVMDALLRQENGVIQGLIQAAGGSPQAIGAAVRNALVKMPAASGSTTSQ
PQASRQLTAALAQAEKEMQQMGDEYVSTEHLLIGIAASAPNQSADILKANGVTAAALRKAVPGVRGGAKVTSPDAEGSYK
ALEKYSTDLTARAKEGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKKLIS
LDLGSMVAGSKYRGEFEERLKSVLNEIKNADGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDEY
RENIEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYISGRQLPDKAIDLVDEAAA
HLRMELDSSPEEIDELQRKVTRYEMEEMQLKKAEDPASKERLEKLQNELANTREKLSGLKARWDAEKAGHNKVGDLRAQL
DAKRVEADKFTREGNLAEASKILYGEIPAIQKQLDAAEKADAEDGATGETKPEPMVPDHVDADSVAGIVSEWTGIPVGRL
MQGENEKLLSMEDYLGKRVIGQKEAIAAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEKAMVR
IDMSEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEVEKANPEVFDVLLQVLDDGRLTDGQGRTVDFKN
TILIMTSNLGSQFLVNQDMDADAKKKAVMDAVHMNFKPEFLNRLDEIVMFHPLTREELGGIVSIQVAQVASRLTDRRIKL
DVTDAAREWLANTGYDPAYGARPLRRLVQTEVGDQLARMLLAGKVHDGDTVLVNQTGGEHLELGTMPEDPDAGSDTDVTV
EDVTEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-106 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 8e-107 42
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-102 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_006393745.1 ATP-dependent chaperone VFG2076 Protein 4e-117 42
clpB YP_006393745.1 ATP-dependent chaperone VFG2084 Protein 7e-110 42