Gene Information

Name : metB (BBB_1323)
Accession : YP_006394794.1
Strain : Bifidobacterium bifidum BGN4
Genome accession: NC_017999
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 1575715 - 1576902 bp
Length : 1188 bp
Strand : -
Note : COG0626:Cystathionine beta-lyases/cystathioninegamma-synthases

DNA sequence :
ATGACCATCACCATCTCCACCAACGCCGCAGCCCTCGCCAACACCACGCTCGCCACCCGTGCCATCCACGCCGGGCAGGA
GCCCGACCCGACCACCGGAGCCGTCGTCACGCCGATCTACATGACCTCCACGTTCAAGCAGGACGGTGTGGGCGGACTGC
GTAACGGTTACGATTACAGCCGGTCCGTCAACCCCACGCGAAACAGCTTCGACGCGCAGCTCGCCGCCGTCGAAGGCGCG
AAATACGCGCTGAGCTTCTCTTCCGGACTTGCCGCGATTGACGTGCTGCTGCGGGCCACGCTGAAGCCGGGCGACAACAT
CCTGCTCGGCAACGACGTGTACGGCGGCACCTACCGTCTGCTCGCCAAGGTGTTCGTGCCGTGGGGCATCGGGCTCGACG
TGGTCGACATCACCGACACTGCCGCCGTCGCCGCCGCGCTTGAAGCCAAGCAATACCGGTACATCTGGGTGGAGACGCCC
TCCAACCCGCTGCTCAACATCACCGACATCGCCGCGACCGCCGACGTCGCGCATCGGCACGGCACCAAGGTCATGGTGGA
CAACACGTTCGCTTCCCCGGCGCTGCAGCATCCGCTCGACGATGGTGCCGACGCGGTCGTGTATTCGACCACCAAGTACA
TCGGCGGGCATTCCGATGTGGTCGGCGGCGCGATCGTGCTCAACGACGAAGAAACCCGCGACGCGGTCGCGTTCCTGCAG
AACGCCGCCGGCGCGGTGCCATCCCCGTTCGACTCGTGGCTGGACATCCGCGGCCTGAAGACCCTGGCCGTGCGAGTGCA
GCGCCACAGCGAAAACGCGCTGAAGATCGCGCAATGGCTGGAAACCCGTCCGGAAGTGGAGCGCGTGTGGTACCCGGGAC
TGGAATCCCACCCGGGTCACGAGATTGCCGCCCGTCAGATGCACGGCGGCTTCGGCGGCATGATTTCCGTGCAGCTCGCG
GCCGGTTTCGAGGCGGCCAAGCGGTTCGCCGGCGCCACGCAGATCTTCACGCTCGCCGAGTCGCTGGGCGGAGTGGAGAG
CCTGATCGAGCACCCGGGCGCGATGACCCACGCCTCAGTGGCCGGTACCACGCTGGAGGTGCCCGCGAATCTGGTGCGCC
TGTCCGTCGGCATCGAAGGTGCCGACGACCTGATCGCCGACCTGGAGCAGGCCTTCGCCGCCATCTGA

Protein sequence :
MTITISTNAAALANTTLATRAIHAGQEPDPTTGAVVTPIYMTSTFKQDGVGGLRNGYDYSRSVNPTRNSFDAQLAAVEGA
KYALSFSSGLAAIDVLLRATLKPGDNILLGNDVYGGTYRLLAKVFVPWGIGLDVVDITDTAAVAAALEAKQYRYIWVETP
SNPLLNITDIAATADVAHRHGTKVMVDNTFASPALQHPLDDGADAVVYSTTKYIGGHSDVVGGAIVLNDEETRDAVAFLQ
NAAGAVPSPFDSWLDIRGLKTLAVRVQRHSENALKIAQWLETRPEVERVWYPGLESHPGHEIAARQMHGGFGGMISVQLA
AGFEAAKRFAGATQIFTLAESLGGVESLIEHPGAMTHASVAGTTLEVPANLVRLSVGIEGADDLIADLEQAFAAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-70 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-69 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-52 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_006394794.1 cystathionine gamma-synthase BAC0207 Protein 4e-59 43