Gene Information

Name : Tsac_1363 (Tsac_1363)
Accession : YP_006391969.1
Strain : Thermoanaerobacterium saccharolyticum JW/SL-YS485
Genome accession: NC_017992
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1430743 - 1432494 bp
Length : 1752 bp
Strand : +
Note : KEGG: txy:Thexy_0635 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region

DNA sequence :
ATGCGTAGAACTAAGATAATATGCACGATTGGTCCTGCCAGTGAAAAATATGAGATATTGAAAGAGCTTATAGAAAGCGG
TCTTAATATTTGCAGGTTGAATTTTTCACATGGGGATCATGAAGAGCATGGAAGCAGAATAGACAATATTATAAAGATTA
GAGAAGAACTTAAGCTGCCTATTGCAATTATGCTTGATACAAAAGGGCCTGAAATAAGGACTGGCAGATTTAAAGGCGGT
GTTGCAGAGCTTAAAGAAGGCCAGACATTTACGATAACATCAAGGGAAATTGAAGGAGATAACACTATTTGTTCTGTTTC
ATACAAGGGGCTTCCTCAAGATGTGGAGAGAGGTTCTCGCATATTGATTGATGACGGATTAGTATCATTGAAAGTCAATG
ACGTAAAAGGTGAAGATATAGTATGCACTGTGGAGAATTCTGGTACAATAGGTGATCACAAAGGTGTAAATGTACCTGGT
ACAAAGCTTAATTTGCCTGCCATAACGCAAAAAGACGTGGATGATATAGAGTTTGGAATAAAAAAAGGAATCGACATGAT
TGCAGCGTCTTTTGTCAGAAAAGCAGCAGATGTAATTGCCATAAGGAGATTGTTAGAAGACAATGACGCTGGCCATATAC
TTATCATATCAAAAATTGAAAATCGCGAAGGCGTAGAAAATATTGACGAAATAATCAAAGTCTCTGATGGCATAATGGTA
GCCCGCGGCGATTTGGGTGTCGAAATTCCTATAGAGGAAATACCTATCGTTCAGAAAAGGATAATTGAAAAATGCAACAA
AGCAGGTAAACCAGTAGTTACTGCTACACAGATGCTTGACTCTATGATAAGAAATCCAAGGCCAACAAGGGCAGAAGTAA
CAGATGTAGCCAATGCTATATTGGATGGCACTGATGCGATAATGTTGTCTGGTGAAACAGCGCAAGGCAAATATCCTGTA
GAGGCTTTTAAGACGATGTCAAAGATAGCTGAAAAGATTGAGACGTATATAAATTACAAAGAAAATTTAGATAAAAATGT
GGATTACAATATTTCTATGACAAATGCCATAAGCCATGCTACGTGCACTACCGCGAGAGATATAGGCGCAACTGCCATTA
TTACATCTACAATATCAGGTTATACTGCGAGAATGGTGTCTAAGTATAGACCGTCAGCACCTATAATAGCAGTGACGCCA
AACAAAGATGTTGCAAGAAGGCTTAGCATCGTGTGGGGTGTACATCCATTGATATCACAGGAAGTCAATTCTACAGATGA
AATGATAGAAGTATCAGTAAATACGGCTTTAAATGAAGGATTAATTCGAAATGGCGATATTGTAGTAATATCGGCAGGAA
TACCTGTCGCGACTACAGGCACAACAAATATGTTGAAGGTTCATATTGTGGGAGATGTAATAGTAAAAGGCACAGGCATA
GGCACTAAATCCATAAGTGGTGTTGTTTCCATCATAAGAGATCCATACAAGGACAAAGATAAGTTCAGAGAAGGAGATAT
CATCGTTGCTCAAAAAACTGAAAGGGATTATATGCCTATAATTGAGAAGGCTTCAGCTATCATAACAGAAGAAGGTGGAC
TAACGTCCCATGCTGCAATAGTTGGATTGAACTATGGATTACCTGTCATTGTAGGCTGTGAAGGAGTAACTTCAAAGCTT
AAAGATGGAATGACGGTAACTCTCGATACTGCCAGAGGATTGGTCTACAAAGGTATAGTGAATATAAAATAG

Protein sequence :
MRRTKIICTIGPASEKYEILKELIESGLNICRLNFSHGDHEEHGSRIDNIIKIREELKLPIAIMLDTKGPEIRTGRFKGG
VAELKEGQTFTITSREIEGDNTICSVSYKGLPQDVERGSRILIDDGLVSLKVNDVKGEDIVCTVENSGTIGDHKGVNVPG
TKLNLPAITQKDVDDIEFGIKKGIDMIAASFVRKAADVIAIRRLLEDNDAGHILIISKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPIEEIPIVQKRIIEKCNKAGKPVVTATQMLDSMIRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPV
EAFKTMSKIAEKIETYINYKENLDKNVDYNISMTNAISHATCTTARDIGATAIITSTISGYTARMVSKYRPSAPIIAVTP
NKDVARRLSIVWGVHPLISQEVNSTDEMIEVSVNTALNEGLIRNGDIVVISAGIPVATTGTTNMLKVHIVGDVIVKGTGI
GTKSISGVVSIIRDPYKDKDKFREGDIIVAQKTERDYMPIIEKASAIITEEGGLTSHAAIVGLNYGLPVIVGCEGVTSKL
KDGMTVTLDTARGLVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-95 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-95 49
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-94 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tsac_1363 YP_006391969.1 pyruvate kinase VFG0479 Protein 4e-95 49