Gene Information

Name : metC (HMPREF0351_10471)
Accession : YP_006375077.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 469495 - 470640 bp
Length : 1146 bp
Strand : -
Note : -

DNA sequence :
ATGCACATTCAAACAAAATTGATCCACGGAGGCATCAGTGAAGATCCCACAACAGGAGCTGTCAGTGTACCTATTTATCA
AACATCCACTTATCGGCAAGATGGCGTCGGCCAGCCTAAACAATATGAATATTCAAGATCTGGTAATCCTACTCGTTTTG
CATTGGAAGAACTGATTGCTGATTTGGAAGGCGGTGTTCGAGGATTCGCTTTTTCTTCTGGTCTTTCTGGGATTCATGCC
GTTTTTTCTCTTTTTCAAGCTGGCGATCATATCTTATTAGGAGATGATGTCTATGGAGGAACATTCCGTCTATTTGACAA
AGTTCTTACTAAAAATGGTCTCGAGTACACGATCATAGATACGAGTAATCTTGATAAAATAGAACAATCCATCAAACCCA
ATACAAAAGCACTTTATCTTGAAACACCTAGCAATCCGCTTCTAAAGATTACTGATTTAGAAAAAAGTGCCACTCTGGCT
CATCAACATGGATTGATAGTTATTGCTGACAATACATTTGCTACTCCTTATTTTCAAAGACCTTTAGATCTCGGTTCTGA
TATCGTTGTCCATAGCGGTACCAAATATCTAGGCGGACACAGCGATGTAGTAGCTGGTTTAGTGACTTCTAACCATAAAG
ATCTAGCCGATCAGATCGGATTTTACCAAAATGCTATCGGAGCCGTACTTGGTCCCCAAGATAGCTGGTTACTTCAGCGC
GGAATCAAGACACTAAGTGTTCGTATGGAGGAACATCAAAAAAATGCTTTTGTGGTAGCTGATTTTCTATTTTCTCATCC
AGCAGTAGAAAAGGTCTACTATCCAGGATTACCCGATCATGAACTCCATGGAGTTGCTAAGCAGCAGATGAGCGGCTTTA
GCGGAATGATTTCTTTTACTTTAAAAAATGAAGAATCTGCTATTCCATTTGTTGAATCACTCCAACTATTTACTTTAGCA
GAAAGTTTAGGTGGCGTAGAAAGTTTAGTGGAAATTCCTTCTGTCATGACTCATGCGTCTATTCCAAAAGAAAAACGAGA
AGAGGCTGGCATAAAGGACGGCTTGATCCGTCTTTCTGTAGGAATTGAGTATGGTCAGGATCTCATAAACGATTTAGCTC
AGGCATTTGACAGAATCAAGAACTAG

Protein sequence :
MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEYSRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHA
VFSLFQAGDHILLGDDVYGGTFRLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQIGFYQNAIGAVLGPQDSWLLQR
GIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPGLPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLA
ESLGGVESLVEIPSVMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-100 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-101 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-71 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_006375077.1 cystathionine gamma-synthase BAC0207 Protein 5e-67 43