Gene Information

Name : guaA (HMPREF0351_10034)
Accession : YP_006374640.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 39153 - 40718 bp
Length : 1566 bp
Strand : -
Note : -

DNA sequence :
TTGACAAACGTTGCCGATATGACGAACGTTGAAAAGATTATCGTATTAGACTACGGTAGTCAGTATAACCAATTGATCAC
AAGACGTATTCGTGATCTTGGAGTCTTTTCCGAATTATTGAGCCACCGCATTACTGCAGAAGAAGTAAAAGCGATGAATC
CAAAGGGAATCATTCTTTCTGGCGGACCAAACAGTGTATATGATGAGAATGCATTTGGGATCGATCCTGAGATCTTCAAT
TTAGGTATTCCTGTATTAGGGATTTGCTATGGTATGCAATTGATCACGTACAAACTTGGCGGTTCCGTAGAGCCTGCTAA
AAACCGCGAATATGGGAAAGCCTTGTTAGAAGTAACAAGCGATCAAGCTGTCTTGTTTAAAGAAACACCAAAACAACAAA
CAGTATGGATGAGCCATGGTGACTTGGTAACTAAAGTTCCTGAAGGCTTTGAAACAGTCGGAACAAGCAAAGATTGTCCG
ATTGCTTCTATCCAAGACACAACACGTAATTTTTATGGTATCCAATTCCATGCAGAAGTACGTCATTCCGAATACGGAAT
CGAATTGCTGCGCCACTTTGCCTTTGATGTTTGTCACTGTGAAGGTAACTGGACAATGGATAACTTTATCGATATGCAAG
TAGAAAAAATCCGTGAACAAGTTGGTGACAAAAAAGTCTTGCTTGGTCTTTCAGGTGGCGTTGATTCTAGTGTCGTTGGG
GTTCTTTTACAAAAAGCGATCGGTGACCAATTGACATCTATCTTTGTTGACCACGGTCTGCTACGCAAAGGCGAAGCGGA
ACAAGTAATGGAAAGTCTAGGCGGAAAATTCGGCTTGAACATCATCAAAGTCAATGCAAGAGATCGCTTCTTAGACAAGT
TGAAAGGTGTATCTGACCCAGAACAAAAACGTAAAATCATTGGGAATGAATTCGTATATGTTTTTGATGACGAAGCAACA
AAACTTGCTGGTGAAGAAGGCGTCTCTTTCCTAGCACAAGGAACGTTGTATACTGACGTTATCGAATCTGGTACAGAAAC
AGCACAGACGATCAAATCTCACCATAATGTAGGTGGACTGCCAGAAGATATGCAATTTGAATTGATCGAACCATTAAACA
CATTATTCAAAGACGAAGTCCGTGAATTAGGGACTCAGTTAGGCATGCCTGATTCAATCGTTTGGCGTCAGCCATTCCCT
GGTCCTGGTCTTGGTATTCGTGTTCTTGGCGAAATCACTGAAGACAAGCTAGAAATCGTACGCGAATCTGATGCTATCTT
GCGTGAAGAAATCGCAGCTGCTGGACTTGACCGTGATATCTGGCAATATTTCACTGTTCTTCCAGGGATCCGCTCTGTCG
GTGTTATGGGTGACGGACGTACTTACGACTACACAGTCGGTATCCGTGCTGTAACTTCAATCGACGGAATGACCGCTGAC
TTTGCCCGTATCCCATGGGAAGTCTTGCAAAAAATCTCTGTACGTATCGTAAACGAAGTAGCCCACGTCAACCGTATCGT
GTATGACATCACTTCTAAACCACCAGCAACAGTGGAGTGGGAATAA

Protein sequence :
MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRITAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFN
LGIPVLGICYGMQLITYKLGGSVEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIREQVGDKKVLLGLSGGVDSSVVG
VLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGKFGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEAT
KLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFP
GPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTAD
FARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-179 75
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-179 75
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-179 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-123 51