Gene Information

Name : clpC (HMPREF0351_12685)
Accession : YP_006377291.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Virulence
Product : ATPase/chaperone ClpC, specificity factor for ClpP protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2670924 - 2673416 bp
Length : 2493 bp
Strand : -
Note : -

DNA sequence :
ATGGAAGAACTTTTTACTGAAAGAGCCCAAGCAGTATTAGAAATTGCACAAGAAGAAGCAAAACGGTTGAAACATCAATC
AGTTAGTTCAGAACATGTTTTACTAGCCTTAGTGGTCGAGCAAAATGGAATTGCTGGAAAAGTATTACGTGAAATGGATT
TGAATGAAACGGAAATTTATGAAGAAATTGAACATCTGATTGGTTATGGTGGTATCCGTTCTTACCCTAAAGGAGTCTTT
CTTCCATATTCACCAAGAATGAAACAAGTTTTTGCTTTAGCTAGCAGCGAAGTGAAGAAAACTGGTTCTCAAAAAGTTGG
AACAGAACATATTTTGATGAGCTTATTAAAAGATGAAAGTATCATGGCTACTCGAATCATGATCAACTTAGGTATCAGCC
TTTCAAAAGCCCGTCAAGTTCTGAAACAAAAAATGGGGCTAGCTGGTGATTCTGCTGGAAAAGGAATGAATCGTCGTAGA
AATGTAAATGTACAAGATAAACGGCAAACACCGCAAGGAACACCTACGCTAGATTCATTAGCACGTGATTTGACGAAATT
AGCAAAAGAAAACAAGCTGGACCCAGTTGTTGGTCGTTCGAGAGAAGTGAAACGGCTTATCCAGATTCTTAGCCGACGGA
CAAAGAATAACCCTGTACTGGTGGGTGAACCTGGTGTAGGCAAAACAGCCATTGCTGAAGGGTTAGCTCAAAAAATCATT
TTAGGTGAAGTGCCAGAAGACATGCAAGAAAAGCGCCTGATGATGCTTGATATGGGATCTTTGGTTGCTGGTACGAAATA
TCGCGGTGAATTTGAAGATCGAATGAAAAAGGTCATCGACGAAATCTATAATGATGGTCAAGTAATCTTATTCATTGATG
AATTGCATACCTTAATTGGTGCAGGTGGAGCAGAAGGAGCAATTGATGCTTCGAATATCTTGAAACCGGCGTTAGCTCGA
GGAGAATTACAAACGATCGGAGCAACGACCCTAGATGAATATCAAAAATATATCGAAAAAGATTCTGCATTAGAGCGACG
TTTTGCTCGCATTCAAGTAGATGAGCCAACTCCTGAAGAAGCAGAAGTGATTCTTCAAGGATTACGTACAAGATATGAAG
AGCACCATGGAGTGGAGATCACAGATGAAGCTGTACGAGCAGCAGTCAATCTTTCTGTTCGTTATATCACTTCTCGTCAA
CTACCCGATAAAGCAATTGATTTGATCGATGAATCAGCAGCGAAAGTCCGTTTGGATCAAACCGATCACTTAACAAAATC
AACTGTGATCAAACTAGAAATCGATGAACTAGTACAAGAAAAGGAAGCAGCGATCCAAAAACAAGACTTTGAAAATGCTG
CTCAATTACGCAGACAAGAAAAAGCACTACGTAAAAAGCTGCAAAAAGTTTCTGCAATTGAAGCAAAACAGGAGCAAGGT
TATTCTGATCGTGTAACAGAAGAAGATGTTGCTACAGTTGTATCGGAGTGGACTGGTGTCCCTCTACAGCAGTTGGAGAA
AAAAGAAAGCGAACGCTTGTTAGAACTGGAAGGACTTCTGCATGAACGTGTCGTTGGTCAAGATGAGGCTGTCAAAGCAG
TTTCACGTGCGATCCGCCGTGCACGAAGCGGATTGAAAGATCCTGATCGTCCAATTGGTTCATTCATGTTCCTTGGACCA
ACTGGTGTCGGAAAAACAGAATTGGCCAAAGCACTTTCAGAAGTCATGTTTGGAAGTGAAGATGCCCTGATCCGTGTTGA
TATGTCAGAATTTATGGAAAAATACAGTACAAGCCGATTAATCGGGTCTCCTCCAGGATACGTAGGGTATGATGAAGGTG
GACAGTTGACAGAAAAAATTCGTCAAAAACCATATTCAGTGATTCTCTTAGATGAAGTGGAGAAAGCACATCCAGACGTT
TTCAATTTACTTCTGCAAGTATTGGATGATGGTCATTTAACAGATTCTAAAGGTAGAAAAGTGGACTTTAGAAATACAAT
CATGATTATGACTTCAAATATCGGAGCGACACAAATTCGAGAAGAAAAAAATGTCGGATTCAATGTCCAAGATGTTACTA
AAGATCACAAAGCCATGCAAAAACGTATCTTAGAAGAGTTAAAGAAAGCTTTCCGACCTGAATTCTTGAATCGAATCGAT
GAGACTGTCGTCTTCCATTCATTGAGTAAAGATGAAATCCATACAATCGTCCAAATCATGAGCAAAGCGATTATCAAACG
ATTGAAAGAACAAGATATTCAAGTGAAAATCACACCATCTGCAATCGATGTGATCGGGAAAGCTGGATTTGATCCTGAAT
ATGGTGCACGTCCAATCCGTCGCGCACTTCAAAAAGAAATTGAAGATCGATTGAGCGAGGCTTTGCTTGGCGGAGAAATT
CGTTTAGGTGACCACGTAACAGTAGGTGCTTCAAAAGGTAAGATCACATTGAATGTTCGCGGACCTAAAAAGGAAACAGT
AGGTTCCCTATAG

Protein sequence :
MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGIAGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVF
LPYSPRMKQVFALASSEVKKTGSQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNPVLVGEPGVGKTAIAEGLAQKII
LGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMKKVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALAR
GELQTIGATTLDEYQKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLSVRYITSRQ
LPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDFENAAQLRRQEKALRKKLQKVSAIEAKQEQG
YSDRVTEEDVATVVSEWTGVPLQQLEKKESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGP
TGVGKTELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKPYSVILLDEVEKAHPDV
FNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREEKNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRID
ETVVFHSLSKDEIHTIVQIMSKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGGEI
RLGDHVTVGASKGKITLNVRGPKKETVGSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_006377291.1 ATPase/chaperone ClpC, specificity factor for ClpP protease VFG0079 Protein 0.0 62
clpC YP_006377291.1 ATPase/chaperone ClpC, specificity factor for ClpP protease VFG0080 Protein 9e-147 50