Gene Information

Name : copB (HMPREF0351_11880)
Accession : YP_006376486.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Resistance
Product : P-ATPase superfamily P-type ATPase copper (Cu) transporter
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1840575 - 1842746 bp
Length : 2172 bp
Strand : -
Note : -

DNA sequence :
ATGAATGGGAACGATATGGAGAAAAAACATGAGCATAAAAAAGAAGTAGTAAACAAAGAAAGTACAGAATCTCATGAAAA
ACAGATGGAGATGAAACATGACCATAGTCAGATGGATCATTCCATGCACATGGGACATAACCATGGAGATATAGCAAACA
GCAAACAAATGGACCATTCGATGCACATGGATCACGAACACGGCGGCATGGATCATTCCATGCACATGGGGAATTTCAAA
CAAAAATTTTGGCTATCGCTTATCCTAGCTATCCCAATCATTCTTTTTTCACCAATGATGGGAATGGAATTTCCATTTCA
AGTAACGTTTCCTGGTTCTGATTGGCTCGTATTGATCTTAGCAACTATACTATTTATCTATGGCGGTCAGCCATTTTTAA
GTGGAGCTAAGATGGAATTGAAACAAAAAAGTCCTGCTATGATGACACTGATCGCGATGGGGATTACAGTTGCATATATT
TATAGTGTCTATTCGTTTATCGCAAATCTGCTCAATCCACATACACACGTCATGGATTTCTTCTGGGAATTGGCTACTTT
GATCGTTATTATGCTACTAGGTCACTGGATTGAAATGAATGCTGTGTCGAATGCCAGCAATGCTTTACAAAAACTAGCAG
AATTACTGCCAGAATCAGTGAAACGCTTGACGAAAGATGGAAAAGAAGAGACAGTTTCATTGAAAGAAGTAAACGAAGGT
GATCGTTTGATCGTCCGGTCTGGTGATAAAATGCCAACAGATGGTGTAATCTTGAAAGGTGAAACAATTGTTGACGAATC
AGCTGTGACTGGCGAATCAAGAGGAATCAAAAAACAAGCCAATGACAAAGTGATTGGCGGTTCTATCAATGGGGATGGAA
CGATCGAAATCGAAGTAACTGGAACTGGTGAAAATGGTTATCTAGCGAAGGTTATGGAAATGGTGCGAAAAGCACAAGGA
GAAAAATCCAAGCTAGAGTCATTATCTGACAAAGTGGCAAAATGGCTGTTTTATGTCGCATTAATTGTGGGTATCCTGGC
ATTCATCGCCTGGTTGTTCTTGACAGATCTTCCTAATGCATTAGAACGTATGGTAACAGTCTTTATCATCGCCTGTCCTC
ATGCTCTAGGTTTAGCTATCCCATTAGTTGTTGCTCGTTCCACATCAATAGCAGCTAAAAACGGATTACTTTTGAAAAAC
CGCAATGCACTGGAGCAAGCCAATGATCTAGATGTGATCATGCTGGACAAAACAGGAACACTAACAGAAGGAAAATTTAC
TGTAACGGGTGTCGAAGTACTTGATGATGCGTTCAATAAAAATGAAATCCTTCAATATCTAGGAGCCTTGGAAGCGAATG
CCAATCATCCATTGGCTGTTGGCATTATGAATTATTTGAAAGAACATGAAATCAAGCCTTATCAAGCTGAAAATCTAAAA
AATCTTTCAGGAGTCGGGCTAGAGGCAACAGTCAAAAAACAACAAGTGAAAATAGTTAATGAAAAAGAAGTTGAGCGTCT
CGGATTAAACGTAGAACAAGCATTATTGAAACCTTACCAAGAACAAGGAAATACCATCAGCTTCCTGATTTTAGAAAATC
ATCTAGCTGCAATCGTTGCTTTAGGTGACGTAGTAAAAACAGAAGCAAAAGAATTTATCCGAACATTGAAAGAAAGAAAA
ATCACTCCTGTCATGCTTACTGGTGACAATAAAAACGCTGCCCAAGCAGTAGCAGATTATTTAGGGATCGAAGAATATTA
TGGCGGTTTATTACCAGATGATAAAGAAGCTGTTGTCCAGAAATACCTTGACCAAGGGAAAAAAGTAATCATGGTGGGTG
ATGGGATCAATGATGCGCCAAGTTTAGCCCGTGCTTCAATCGGGATGGCAATCGGTGCAGGGACAGATATCGCAATCGAT
TCTGCGGATGTCGTATTGACAAACAGCGATCCAAAAGATATTTTGCATTTTCTTGATCTAGCCAAGCAAACGCGAAAGAA
AATGATCCAGAACCTCTGGTGGGGGGCAGGTTACAATATTCTTGCAATTCCGCTAGCAGCCGGAATTCTTGCGCCAATTG
GTATCATATTAAGTCCAGCAGTTGGTGCTGTCTTGATGTCGTTAAGTACGGTAGTTGTAGCTCTAAATGCTTTGACATTG
AAAATCAGATAA

Protein sequence :
MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHMGHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFK
QKFWLSLILAIPIILFSPMMGMEFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPESVKRLTKDGKEETVSLKEVNEG
DRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGIKKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQG
EKSKLESLSDKVAKWLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLLLKN
RNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALEANANHPLAVGIMNYLKEHEIKPYQAENLK
NLSGVGLEATVKKQQVKIVNEKEVERLGLNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERK
ITPVMLTGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARASIGMAIGAGTDIAID
SADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAIPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTL
KIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 3e-124 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copB YP_006376486.1 P-ATPase superfamily P-type ATPase copper (Cu) transporter BAC0079 Protein 0.0 86
copB YP_006376486.1 P-ATPase superfamily P-type ATPase copper (Cu) transporter BAC0383 Protein 9e-148 50
copB YP_006376486.1 P-ATPase superfamily P-type ATPase copper (Cu) transporter BAC0629 Protein 3e-126 44