Gene Information

Name : HMPREF0351_11819 (HMPREF0351_11819)
Accession : YP_006376425.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Unknown
Product : RNA-directed DNA polymerase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.49
Position : 1789553 - 1791463 bp
Length : 1911 bp
Strand : -
Note : -

DNA sequence :
ATGCCTAAAAATAAAAATGAAACATTGTGTGTAGAAGATTTAAGACACGCTGAATATTACGAAATGCAAAACACCTTTGA
TGATTTATATGCCAAAAGTAAGAATGGAGATATTTTCACTCATCTTATGGATATTATCCTATCGAGAGAAAATATATTAC
TGGCATATCGAAATATCAAAGCAAATGCAGGCAGTAAAACAGCAGGAACAGACGGTACAATAATTAAAGATATTGGCAAA
TTGCCAGCAGAAACAGTTGTCAAAAAAGTAAGATACATTGTTGCAGGCAGTCCACATGGGTATCGACCTAAGCCAGTGAG
GCGAAAAGAAATACCAAAACCAAATGGTAAAACCAGACCTCTAGGTATTCCTTGTATGTGGGACAGGCTTATACAACAAT
GTATAAAACAAGTATTAGAACCAATCTGCGAAGCTAAATTTAGTGAAAACAGCTATGGTTTTAGACCTAATAGGTCAGTT
GAAAATGCAATAAAAGCAACCTATAACCGCCTACAAATCAGCCAGCTACATTATGTGATTGAATTTGATATTAAGGGTTT
CTTTGACAACGTGAACCATTCCAAGCTGATAAAACAGATATGGGCTATGGGAATACGGGACAAGCACTTGATATTCATTT
TAAAAAGGATATTAAAAGCTCCAATCAAAATGACTAACGGTACAATAACATATCCAGAGAAAGGAACTCCGCAAGGGGGA
ATAATATCCCCACTACTAGCAAACATTGTTCTTAATGAGTTAGACCATTGGGTAGAAAGCCAATGGCAGGAAAATCCTGT
TACAAAAAACTATGTGGTTCATATCAATAAAAGCGGTAGCCCATGTAAAAGCAACGCTTACAAAGAAATGAAGAAAACAA
AGTTAAAGGAAATGTATATGGTTCGTTATGCAGATGATTTTAGAGTTTTCTGCCGCTACAAGGAAAGTGCTGAAAAAGCC
AAAATAGCAATCACTCAATGGATTGAACAACGATTAAAATTGGAAGTATCACAAGAAAAAACAAGAATTGTAAATGTTAG
AAAAAGATACTCCGACTTTCTTGGTTTCAAGATTAAAATGATACCGAGAAGAAAGAAGTTAGTTGTTAAATCACATATAA
GTGATAAACAATTCAAAAACCAAAAAGACAAGCTGGTATCACAGGCAAAGAAAATTGCTTCTCCCTCAAAAGGGAAAACG
GAATTAGAAGAAACAAGACTTTATAATTCAATGGTATTAGGTATGCAAAATTATTATCAGATTGCAACGAATGTAAATCT
GGATTGTATGAAACTGAATAGAGCTGTAATGGCTATCTTCACTAACAGATTAGGTACAAACAAAAGGGGCAGATTGAGAA
AAACAGGCAGACAACTTACGACAAAGGAGGCAACAAGATATGGTAAATCTAAAATGCTTCGGTATGTTGCTGGCGAGGGC
GAACCTATTTTCCCTGTTGGATATATCCAACACAGAAAACCAATGGCAAAGGTGTATTTAGCGAATTGCTACACTCTAGA
GGGAAGAAAATTTATCCACACCAATCTAAGTGTTGATAAATTACTGATGTACCAGTTAATGAAATTATCTTTGGAAAATC
GCACAATAGAATACGCAGACAATCGAATTTCGCTATTTTCTGCTCAACATGGAAAATGTGCTATAACTCTGGAAGAATTT
CAACAAGCTAATGAAATACATTGTCATCATATTGTACCAACTGGAGCTGGTGGAAATGACGATTATAAAAATCTTATTTT
GGTAAAAGAGGCGGTACACCGTCTAATACACGCTAAAACAGAAGAAACAATACAAAAATATATAGCTCTATTGAAGCTAA
ATAAAGTCCAGCTCATAAGACTAAATAAATATAGAGTATTAGCTGGCAATCAAGAATTAAACTTGATATAG

Protein sequence :
MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMDIILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGK
LPAETVVKKVRYIVAGSPHGYRPKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRILKAPIKMTNGTITYPEKGTPQGG
IISPLLANIVLNELDHWVESQWQENPVTKNYVVHINKSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKA
KIAITQWIEQRLKLEVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKIASPSKGKT
ELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEG
EPIFPVGYIQHRKPMAKVYLANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEF
QQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKYRVLAGNQELNLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2326 NP_815981.1 group II intron reverse transcriptase maturase Not tested Not named Protein 5e-143 50
ef0012 AAM75218.1 EF0012 Not tested Not named Protein 1e-98 41