Gene Information

Name : pyk (HMPREF0351_11002)
Accession : YP_006375608.1
Strain : Enterococcus faecium DO
Genome accession: NC_017960
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 982334 - 984118 bp
Length : 1785 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAACCAAAATCGTTAGTACATTAGGACCAGCAAGTAACTCAGTAGAAATTATTTCTCAATTGATTGAATCTGG
GGCAAATGTCTTCCGCTTTAATTTTTCTCATGGTGACCATGAAGAACAATTATCACGTATGACTATGGTCCGTGAAGCAG
TTAAAAAGACAGGAAAAGATGTCGGTATTCTTTTAGATACAAAAGGAGCTGAAATCCGTACAACTGTTCAAGGCACAACA
GAAGCTGATTTTGGTCGTGCAGGATACATCAAATTTGAAGTAGGAGATCAAACACGCATCTCTATGGATCCTGAACATGT
AGGTTCAAAAGAAAAAATCGCGGTTACTTACCCAGGATTATTTGACGATGTTCACGTTGGCGGACACATTTTATTTGATG
ATGGTTTGATCGATATGCAAATCATTGAAAAAGACGAAGCAAACCGTGAATTAGTCGTAGAAGTTAAAAATGCAGGTATG
CTAGGATCACGTAAAGGGGTAAATGCACCAGGCGTTTCTATTAGTTTGCCAGGTATTACTCCAAAAGATGCTGACGATAT
TCGTTTTGGTTTAGACAACGATATCGACTTTATCGCTGCAAGTTTTGTACGTAAAGCACAAGACGTTCTAGATATCCGCG
AAATCTTAGAAGAAAAAGACATGACTCATGTTCAAATCTTCCCTAAAATCGAATCTCAAGAAGGTATCGACAACATTGAC
GAAATCATCAAAGTTTCTGACGGTGTTATGATTGCCCGCGGAGATATGGGTGTTGAAATCCCAGCTGAACTAGTACCAAT
GGTTCAAAAACGCATTATCAAAAAATGTAATGCTGCTGGTATCCCAGTTATCACTGCTACACAAATGTTAGAATCAATGC
AAGAAAACCCACGTCCAACACGTGCGGAAGCTTCTGACGTTGCTAACGCTGTATTTGATGGCACAGATGCAACAATGCTA
TCTGGTGAATCTGCAAACGGGGACTACCCAGTTGAAGCTGTTTCAACAATGGCACGTATCGACCAAGAAGCTGAAAATGC
ATTATCAGAATTAGGTACATTCCAATTGAACGAATTCGATAAAACAGATGTAACTGAAACAATCGGTTTATCTGTAGCTC
GTGCTGCAAAAAATCTAGGCGTGAAAACAATCGTTGCTGCAACTGAATCAGGATACACTGCAAAAATGATTTCAAAATAT
CGTCCAGATGCAGATATCTTGGCTGTTACTTTTGACGAACGCACAAAACGTGGTTTGATGTTAAACTGGGGCGTTTACCC
AACAGTTGCTGAAAAACCATCAACAACTGATGAAATGTTTGAACTAGCAGCTAAAAAAGCTGTTGAATTAGGTTTCGCAT
CAGAAGGCGATTTAATCTTGATCACTGCTGGTGTACCAGTTGGTGAACGCGGAACAACTAACGTGATGAAAATTCAAATG
ATTGGTTCTAAATTATTAGAAGCTCAAGGCGTTGGACAAAAATCTGTCGTTGCAAATGCAGTTATTGCTTCATCTGCTGA
AGAAGCTGTAAAAAAAGCAAAAGACGGAATGGTTCTAGTTGTACCATCAACTGACAAAGAATATATGCCTGCAATCGAAA
AAGCAGCTGCTGTTATCGTTGAAGAAGGCGGATTGACTTCTCACGCTGCAGTTGTAGGAATTGCACAAGATATTCCTGTA
ATCGTTGGTGCTAAAGGCGCAACAACAACAATTACAGAAGGTGAATTGATTACCGTTGATTCACGTCGCGGCATCGTTTA
CCGTGGCGAAACAACAGCTATCTAA

Protein sequence :
MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQLSRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTT
EADFGRAGYIKFEVGDQTRISMDPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEEKDMTHVQIFPKIESQEGIDNID
EIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKCNAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATML
SGESANGDYPVEAVSTMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGYTAKMISKY
RPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVELGFASEGDLILITAGVPVGERGTTNVMKIQM
IGSKLLEAQGVGQKSVVANAVIASSAEEAVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPV
IVGAKGATTTITEGELITVDSRRGIVYRGETTAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-88 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-88 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-88 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-88 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006375608.1 pyruvate kinase VFG0479 Protein 2e-88 46