Gene Information

Name : cadA (TMO_c0083)
Accession : YP_006373675.1
Strain :
Genome accession: NC_017958
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 78446 - 81247 bp
Length : 2802 bp
Strand : -
Note : -

DNA sequence :
ATGGATTGCCGCAATGAGGAAGCACTGGTGCGGCGAACGCTGGAGGGCATGCCCGGTGTCGAGCGGCTCCTGTTCGATCT
TCCGCAGCGTTTGTTGACCATTTCGCACCGCGAAGTCTCGGCCGATGCCTTGGAGCAAGCGCTGAATTCGGTGGGCATGA
AGGCTCAGGCTGTCCGAGACGCCGCCGTGTCGACCACCTACCGCATCGAGAACATGGACTGCCCGAGCGAGGAGAAACTC
ATCCGCTCGCACCTCGGGGCAGTCGAGGGAATTCAGGACCTCGACTTCGACCTCGCTGAGCGCACCCTGTCGGTGAAACA
CCTCGCTCAGGCACGCGCGCAGATGGAGCAGGTCCTGGCCTCGATCGGCATGCGCGCCAAGGAGCAGACCTTCGGCCACA
CGGGGCCGATCGAAGCCGCGGCTGTGATCCCATCCTCGGCCCTGCAGCAGCAACCAACCGCTGCCGTTTCCGCGCCGCCG
ATCGGCGAGCGGGTGACGTACCGGATCGAGAACATGGATTGCCCGACGGAAGAAGCGCTGATCCGCGACCGGCTGGGCAA
GCTGCCGGGTGTGACCGCGCTCGACTTCAATCTGATGCAGCGTGTGCTGGGAGTCCAGCACACGCTGGCGACCTCAGCGC
CGATCGAGAAGGCGCTTGCTTCCATTGGAATGCAGGCTGCGCGGCAGGACATGCAGACAGCCACCACGGTACTTCGCATC
GCGAAGATGGACTGTCCGACCGAGGAAAGTCTGATCCGCGGCAAGCTGCAAGGCATGCCGGGCGTGCAGGGAATGGATTT
CAACCTGATGCAGCGCACGCTCACGGTTCGGCACACACCCGACGCGATCAAGCCGGCAGTCGAAGCCATCGAATCGCTGG
GCATGGAAGCCGAGGTCCAGAGGACTGATGAGCCGCGCGATGCCCCGGTGGCCGCGCACAAGACCAATTGGTGGCCGATG
GCGGTTTCGGGCGTTGCGGCGGTGGCCGCCGAAGGCGTGTACTGGGTCAACGACGGCAATCATTGGGCCGTGATCGTGCT
GGCACTGGTTTCGATCTTCACCGGCGGCCTCAGCACCTACAAGAAGGGCTGGATCGCGCTGAAGAACCTCAACCTGAACA
TGAACGCCCTGATGGCCATCGCGGTCACCGGCGGCATGGCGATCGGCCACTGGCCGGAGGCCGCCATGGTCATGTTCCTG
TTCGCGTTGGCGGAAGTGATCGAGGCGAAGTCGCTGGACCGCGCCCGCAACGCCATTCGGGGGCTGATGGACTTGGCGCC
CGAGACCGCGACCGTGCGGCAGGCCGATGGCTCATGGACAGAGCTGCCGGCCAAGGAGGTCGCAAAGGGCGCGGTGGTCC
GCGTGCGTCCTGGCGAGCGCATCGCACTGGACGGCCTGATCACCTCGGGTCGATCGGCCATCAACCAGGCGCCCATCACC
GGCGAGAGCCTGCCCGTCGAGAAGGCCGAAGGTGACCAGGTCTTCGCCGGAACCATCAATGAGACCGGCTCTTTCGAATA
CAAGGTGACCGCAGGCGCCAGCGACTCGACGCTCGCGCGCATCATCCATGCCGTGGAGTCCGCGCAGGGCAGCCGTGCGC
CCACGCAGCGCTTCGTCGACCAGTTCGCCCGCGTCTACACGCCGGCGGTGTTCGCGGTGTCCGTGCTGGTTGCCGTCGTG
CCGCCGCTCGCCTTCGGCGGCGCATGGTTTGACTGGGTCTACAAGGCCCTGGTACTGCTGGTGATCGCCTGCCCCTGCGC
TCTGGTCATCTCCACGCCGGTCACCATCGTCAGCGGCTTGGCCGCTGCCGCCCGACGCGGCATCCTGATCAAGGGTGGCG
TCTACCTGGAGGGCGGGCGCAAGCTCAAGGCGTTGGCCCTGGACAAGACCGGCACACTCACACATGGCAAGCCCGAGCAG
ACCGACTTCGTGCCGCTGATCGGCGAGGCGCAGGAAGTTGCCGCCTGGGCCGCAAGCCTCGCGGCACGCTCGGACCATCC
TGTGTCTCAGGCCATCGCCCGCAAGGCGAACCGTGACGGCATCGCGCTGCACGAGGTCGACGACTTCGCGGCGCTGCCTG
GCCGCGGCGTGCGCGGCCGCGTCGCCGGGCGCATGTTGCACATGGGCAACCACAGGCTCGCCCAGGAGCTGGGCCTGAGC
GAAGCGACGCTCCAGGCTCGGCTGGAGACCCTGGAGCGCCAAGGCAAGACAGCGATCCTGCTGATGGACGATGCGACCGT
GCTCGGCATTTTTGCAGTGGCCGACACCGTGAAGGAAACCAGCCGTGAGGCGGTGGCCGACCTGCAGGCGCTGGGTGTGC
GCACGCTGATGCTGACGGGGGACAACCAGCACACGGCCGCGGCCATCGCTGCCCAGGTCGGAATCTCTGAAGCCCGTGGT
GACCAACTGCCCGAAGACAAGCTCAAGACCATCGAAAGCCTGGTCGGCGGCGAGGGCCAGGTGGGCATGGTGGGCGACGG
CATCAACGATTCGCCCGCGCTCGCCCGTGCCGACATCGGCTTCGCCATGGGCGCGGCCGGCACCGACACCGCGATCGAAA
CAGCCGACGTCGCCCTGATGGACGACGACCTGCGCAAGATCCCCGCCTTCATCCGGCTGTCGCGTAGCACTGCGGCGATC
CTCACGCAGAACATCGTTCTGGCCCTTGGCATCAAGGCGGTGTTCCTTGCGTTGACGTTCACAGGGCATGCCACCATGTG
GATGGCTGTGTTCGCTGACATGGGGGCAAGTCTTTTGGTTGTCGTCAATGGGCTGCGCCTCCTGAAGTTCAAGGCGGCAT
GA

Protein sequence :
MDCRNEEALVRRTLEGMPGVERLLFDLPQRLLTISHREVSADALEQALNSVGMKAQAVRDAAVSTTYRIENMDCPSEEKL
IRSHLGAVEGIQDLDFDLAERTLSVKHLAQARAQMEQVLASIGMRAKEQTFGHTGPIEAAAVIPSSALQQQPTAAVSAPP
IGERVTYRIENMDCPTEEALIRDRLGKLPGVTALDFNLMQRVLGVQHTLATSAPIEKALASIGMQAARQDMQTATTVLRI
AKMDCPTEESLIRGKLQGMPGVQGMDFNLMQRTLTVRHTPDAIKPAVEAIESLGMEAEVQRTDEPRDAPVAAHKTNWWPM
AVSGVAAVAAEGVYWVNDGNHWAVIVLALVSIFTGGLSTYKKGWIALKNLNLNMNALMAIAVTGGMAIGHWPEAAMVMFL
FALAEVIEAKSLDRARNAIRGLMDLAPETATVRQADGSWTELPAKEVAKGAVVRVRPGERIALDGLITSGRSAINQAPIT
GESLPVEKAEGDQVFAGTINETGSFEYKVTAGASDSTLARIIHAVESAQGSRAPTQRFVDQFARVYTPAVFAVSVLVAVV
PPLAFGGAWFDWVYKALVLLVIACPCALVISTPVTIVSGLAAAARRGILIKGGVYLEGGRKLKALALDKTGTLTHGKPEQ
TDFVPLIGEAQEVAAWAASLAARSDHPVSQAIARKANRDGIALHEVDDFAALPGRGVRGRVAGRMLHMGNHRLAQELGLS
EATLQARLETLERQGKTAILLMDDATVLGIFAVADTVKETSREAVADLQALGVRTLMLTGDNQHTAAAIAAQVGISEARG
DQLPEDKLKTIESLVGGEGQVGMVGDGINDSPALARADIGFAMGAAGTDTAIETADVALMDDDLRKIPAFIRLSRSTAAI
LTQNIVLALGIKAVFLALTFTGHATMWMAVFADMGASLLVVVNGLRLLKFKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 100
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-111 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-114 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-114 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_006373675.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 71