Gene Information

Name : metB (MODMU_4606)
Accession : YP_006368451.1
Strain : Modestobacter marinus BC501
Genome accession: NC_017955
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 4600613 - 4601776 bp
Length : 1164 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 87326410, 90148970, 9843488; Product type e : enzyme

DNA sequence :
ATGAGCTCCCGAGTCGATGCGCAGGGCTTCAACACCCGCGCCATCCACGCCGGCCAGGAACCGGACCCGGCGACCGGTGC
GGTCATCCCGCCGCTGCACCTGACGACCACCTACAAGCAGGACGGCGTCGGCGGGCTGCGCGGCGGGTACGAGTACAGCC
GCAGCGCCAACCCCACCCGGGACACCCTGCAGACGGCGCTGGCCGCGCTCGAGCAGGGCACCCGCGGGTTCGCCTTCGCC
TCCGGGCTGGCGGCCGAGGACACCCTGCTGCGCACCGTCTGCCGACCGGGCGACTCGATCGTGCTCGGCGGCGACGCCTA
CGGCGGCACCTACCGGCTCATCTCCAAGGTGCTCGAGCCCTGGGGCATCAGCCACCAGCCGGTCGACCTCAACGACCTCG
ACGCCGTCCGCGCCGCCGTGGCCCCGGAGACCACCCGGGTGGTCTGGTGCGAGACGCCCAGCAACCCGCTGCTCAACATC
TCCGACATCGCCGCGCTGGCCGAGATCGCGCACTCCTCGGGCACGCTGCTGGTGGTCGACAACACCTTCGCCAGCCCGTA
CCTGCAGCAGCCGCTGACGCTGGGCGCCGACGTCGTCGTCCACTCGACGACGAAGTACCTCGGCGGGCACTCCGACGTCG
TCGGGGGCGCGCTGGTCGTCTCCGACGCCGAGCTGGGCGAGCGGCTGGCCTACCACCAGAACGCGATGGGCGCGGTCGCC
GGCCCGTTCGACTCATGGCTGGTGCTGCGCAGCCTGAAGACGCTCGGCGTCCGGGTGGAGCGGCACAGCGCCAACGCCGG
CCGGATCGCCGAGTGGCTGCTGGAGCACCCCGCCGTGGGCGACGTCCTCTACCCGGGCCTCCCCCAGCACCGCAACCACG
ACATCGCGGCGAAGCAGATGTCCGGCTTCGGCGGGATGCTCTCGTTCCGGCTGCGCGGCGGTGAGGAGGCGGCGCTGCGG
GTGTGCGAGCGCACGTCGCTGTTCACGCTGGCCGAGTCCCTCGGCGGCGTCGAGTCGCTGATCGAGCACCCGCACCGGAT
GACCCACGCCAGCGCCGCCGGGTCGCCGCTCGAGGTGCCCGCCGACCTGGTCCGGCTGTCGGTCGGCATCGAGGACGTCG
AGGACCTCCTCGCCGACCTGGAAGGAGCGCTGGGAACTCACTGA

Protein sequence :
MSSRVDAQGFNTRAIHAGQEPDPATGAVIPPLHLTTTYKQDGVGGLRGGYEYSRSANPTRDTLQTALAALEQGTRGFAFA
SGLAAEDTLLRTVCRPGDSIVLGGDAYGGTYRLISKVLEPWGISHQPVDLNDLDAVRAAVAPETTRVVWCETPSNPLLNI
SDIAALAEIAHSSGTLLVVDNTFASPYLQQPLTLGADVVVHSTTKYLGGHSDVVGGALVVSDAELGERLAYHQNAMGAVA
GPFDSWLVLRSLKTLGVRVERHSANAGRIAEWLLEHPAVGDVLYPGLPQHRNHDIAAKQMSGFGGMLSFRLRGGEEAALR
VCERTSLFTLAESLGGVESLIEHPHRMTHASAAGSPLEVPADLVRLSVGIEDVEDLLADLEGALGTH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 49
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-76 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-59 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_006368451.1 cystathionine gamma-synthase BAC0207 Protein 9e-66 43