Gene Information

Name : guaA (LLNZ_05195)
Accession : YP_006356434.1
Strain : Lactococcus lactis NZ9000
Genome accession: NC_017949
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 973474 - 975015 bp
Length : 1542 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
TTGTCCGACACTACACTTGAAAAAATCATTGTACTCGACTATGGTTCACAATACAATCAACTTATTGCGCGTCGTATCCG
AGAAATCGGTGTTTTCTCAGAACTCATGAGTCACAAAGTCACAGCCAAAGAAATTCGTGAGATTAATCCAATCGGTATTA
TTCTTTCAGGCGGTCCAAATTCAGTTTATGATGAAGGTTCATTCGATATTGACCCTGAAATCTTCGAACTTGGTTTGCCA
GTTCTTGGTATTTGCTACGGCATGCAATTGATGAGCTACAAACTTGGCGGTATGGTAGAAGCAGCAGGCGAACGCGAATA
CGGCGTTGCACCACTTCAACTCACTGAAAAATCAGCATTGTTTGCAGGAACTCCAGAAGTTCAAGATGTTTTGATGAGCC
ATGGTGACCGTGTAACAGCTATTCCTGAAGGTTTCCACGTTGTCGGAACTTCACCAAACAGTCCATTTGCTGCCGTTGAA
AACACTGAACGCAATTTGTACGGCATCCAATTTCACCCAGAAGTTCGTCATTCAGTTCACGGAACAGAAATGCTCAGAAA
CTTTGCGCTTAACATCTGTGGAGCCAAAGGGAACTGGTCAATGGAAAACTTCATTGATATGCAAATCAAAGATATTCGTG
AAAAAGTTGGCGACAAAAAAGTACTCCTTGGACTTTCAGGCGGTGTAGATTCATCAGTTGTGGGTGTTCTTTTACAACGT
GCCATTGGTGACCAATTGACATCAATCTTTGTTGACCACGGTTTCCTTCGTAAAGGCGAAGCTGACCAAGTCATGGAAAC
ATTGGGCGGAAAATTTGGTCTTAATATCATCAAAGTAGATGCTCAAAAACGTTTCATGGACAAACTTGTTGGCCTTTCAG
ACCCAGAAACAAAACGTAAAATTATCGGTAACGAATTTGTTTATGTTTTTGATGATGAAGCAAACAAATTAGAAGGTGTT
GACTTCCTTGCTCAAGGAACACTTTACACCGATGTCATTGAATCAGGAACAGATACAGCTCAAACAATTAAGTCACACCA
TAATGTTGGTGGACTTCCAGAAGACATGCAATTCCAATTGATTGAACCATTGAACACACTTTTCAAAGATGAAGTTCGTG
CGCTTGGAACACAACTTGGAATGCCTGATGAAATTGTTTGGCGTCAACCTTTCCCAGGTCCAGGACTTGCCATTCGTGTC
CTTGGTGATTTAACAGAAGAAAAATTAGAAACTGTTCGCGAATCAGACGCAATTCTTCGCGAAGAAATTGCTGCTTCAGG
ACTTGAACGTGATGTTTGGCAATATTTCACAGTAAATACAGACGTGAAATCAGTCGGTGTCATGGGAGACCAACGGACAT
ATGACTATACATTAGCCATCCGTGCCATCACTTCAATTGATGGGATGACAGCAGACTTTGCCCAACTTCCTTGGGATCTT
CTCCAAAAAATCTCAAAACGTATCGTCAATGAGGTTGACCACGTCAACCGTATCGTCTACGATATTACGAGCAAACCACC
AGCAACTGTTGAGTGGCAATAG

Protein sequence :
MSDTTLEKIIVLDYGSQYNQLIARRIREIGVFSELMSHKVTAKEIREINPIGIILSGGPNSVYDEGSFDIDPEIFELGLP
VLGICYGMQLMSYKLGGMVEAAGEREYGVAPLQLTEKSALFAGTPEVQDVLMSHGDRVTAIPEGFHVVGTSPNSPFAAVE
NTERNLYGIQFHPEVRHSVHGTEMLRNFALNICGAKGNWSMENFIDMQIKDIREKVGDKKVLLGLSGGVDSSVVGVLLQR
AIGDQLTSIFVDHGFLRKGEADQVMETLGGKFGLNIIKVDAQKRFMDKLVGLSDPETKRKIIGNEFVYVFDDEANKLEGV
DFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRALGTQLGMPDEIVWRQPFPGPGLAIRV
LGDLTEEKLETVRESDAILREEIAASGLERDVWQYFTVNTDVKSVGVMGDQRTYDYTLAIRAITSIDGMTADFAQLPWDL
LQKISKRIVNEVDHVNRIVYDITSKPPATVEWQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-171 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-171 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-171 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-122 50