Gene Information

Name : metB2 (HFX_2939)
Accession : YP_006350590.1
Strain : Haloferax mediterranei CGMCC 1.2087
Genome accession: NC_017941
Putative virulence/resistance : Resistance
Product : cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 2847405 - 2848610 bp
Length : 1206 bp
Strand : -
Note : -

DNA sequence : 
ATGAACGATTATGAACTACACCGCGAAACGCTCGCGGTGACCCATGGTGAACGCGGCCAGCTGCCCGCGCCGGGGGTCGA
GGATGTTACTGTTCCGGTCCACCTCTCGTCGACGTATTCGATTCCCGACGTGGACCCAGACGCGGACCTGGAGACGCTCG
ACCCCGACGCGGGCGAGTACCTCTACTCGCGGTTGTCGAACCCGACGCGGAATGCGCTGGAACACCGGCTTGCGGCACTC
GAAGGTGGCGAACACGCGCTCGCGTTCGTCTCCGGGACGGCGGCCATTGCCGCGACCATGACGGCGGTGGTCCACCCCGG
CGACCACATCGTTGCGTTCGAAGACCTCTACGGTGGTACGAAGACGATGCTGAACCGCCTGTTCGCCGAGCGACTCGACG
TGGACGTGACGTTCGTGGACGCGACGGACACCGAAAACGTCGAGGCCGCAATGCGCGACAACACGCGTCTCGTCTGGATG
GAGACGCCGTCGAACCCGCTCATGCACCTCTGTGATGTCGAGGCCATTGCGGCCATCGCCGACGAGTGGGACGCCGTCTT
CGGCGTGGATAACACCTTCCTCAGCCCGTACTTCCAGAATCCGCTGTCGCTCGGTGCCGACGTGGTCGTCCACAGCACCA
CGAAGTACCTCAACGGTCACTCCGACTCTATCGGTGGTGCGGTCGTCACCGACCGCGACGACATCATGGACGAACTCGCG
TTCCTCCAGCGTGTCGGCATGGGGTCGATGCTCTCGCCGTTCGACTCCTATCTGACACTTCGCGGTATCAAGACGCTTCC
CCTGCGGATGCGCCAGCACGAGGAGAACGCGATGGAAATCGCGCAGTACCTCGAATCCCACGACGCTGTCACGCGCGTTC
TCTACCCGGGTCTCGAATCGCACCCACAACACGACCTCGCCGCCCGCCAGCAGTCCGGGTTCGGCGGCGTCCTCTCGTTC
GAACTCGACACCGACCTCGACGGGACGGCCGAGTTCCTCGGGAACCTCGACGAGTTCCCGCTCGCGGTCAGCCTCGGCGG
CGTTGAGAGCCTCATCGAGCACCCGGCGACGATGACGCACTCGCCGCTCTCACAGACCGAACGCGACAGACTCGGCATCT
CGGATTCCTTCCTCCGACTGTCCGTGGGCGTCGAACACGTCGATGACCTGATTTCGGACCTCGACGAAGCGCTGTCGACG
GTCTAA

Protein sequence : 
MNDYELHRETLAVTHGERGQLPAPGVEDVTVPVHLSSTYSIPDVDPDADLETLDPDAGEYLYSRLSNPTRNALEHRLAAL
EGGEHALAFVSGTAAIAATMTAVVHPGDHIVAFEDLYGGTKTMLNRLFAERLDVDVTFVDATDTENVEAAMRDNTRLVWM
ETPSNPLMHLCDVEAIAAIADEWDAVFGVDNTFLSPYFQNPLSLGADVVVHSTTKYLNGHSDSIGGAVVTDRDDIMDELA
FLQRVGMGSMLSPFDSYLTLRGIKTLPLRMRQHEENAMEIAQYLESHDAVTRVLYPGLESHPQHDLAARQQSGFGGVLSF
ELDTDLDGTAEFLGNLDEFPLAVSLGGVESLIEHPATMTHSPLSQTERDRLGISDSFLRLSVGVEHVDDLISDLDEALST
V

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-52 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-53 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-47 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB2 YP_006350590.1 cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) BAC0207 Protein 1e-49 44