Gene Information

Name : metC (HFX_2761)
Accession : YP_006350425.1
Strain : Haloferax mediterranei CGMCC 1.2087
Genome accession: NC_017941
Putative virulence/resistance : Resistance
Product : cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 2682692 - 2683852 bp
Length : 1161 bp
Strand : +
Note : -

DNA sequence : 
ATGTCTGAAGACGAGCGACGCATCGAGACGCGCGCCATCCACGCGGGTCAGGAACCCGACGAAGAGACCGGGGCGCTCAT
GACGCCCATCTACGCGAACTCCACGTACGCACAGGACGGTCCCGGCGACCACCGCGGATACGAGTACTCCCGAACGGGGA
ACCCGACGCGAACTGACCTCGAATCGAACCTCGCAGCGCTCGAAAACGGGTCGTACGGTCGCGCGTTCTCCTCGGGGATG
GGTGCGATAAACACCGTGCTCAACCTGCTCGAAGCGGGCGACCACGTCGTCGCCGGCAACGACGTGTACGGCGGAACCCA
CCGCATCTTCACGCAGGTCTACGAGAAGTACGACCTCGAATTCGACTTCGTCGAGACGACCGACCACGACGCGGTCCGCG
ACGCGGTCCGCGACGAGACGGCGCTCGTGTGGGTCGAAACACCGACGAACCCGCTCATGCGCGTCAACGACATCGAAGCG
CTGGCGGACATCGCACACGAGGTCGACGCACTCTGTGCCGTCGACAACACCTTCGCGACGCCGTATCTCCAGCGCCCGCT
CGACCTCGGCGCGGACATCGTCTCGCACTCCTTGACGAAGTATCTCGGCGGCCACTCCGACATCGTCGGCGGCGCGCTCA
TCACCGACGACGAAGAACTCGACGAGGAAATCGCCTTCTACCAAAACTCCGTCGGTGCGACGCCGTCGCCGTTCGACTGC
TTCCTCGTCCTCCGCGGGGCGAAGACGCTCCCGGTTCGGATGGACCGCCACTGCGACAACGCCCGCGACCTCGCCACGTG
GCTCGACAACCACGACGCGGTCGAAACCGTTCACTATCCCGGACTCGACTCCCACCCGCAACACGAACTCGCGGCCGAAC
AGATGGACGATTTCGGCGGTATGCTCTCGTTCGAACTCGACGGGACGCTCGAACAGGCGTCGACCGTCGTCGAGGAGACC
GAGGTGTTCACCCTCGCCGAAAGTCTTGGCGGCGTCGAGAGCCTCATCGAACAGCCGGCGGCGATGACCCACGCGGCCAT
CCCCCGCGAAGAACGCCTCGAAGCCGGTCTCACCGACGGTCTCATCCGCGTCTCCGTCGGCATCGAGCACATTGACGACA
TGAAGGCGGACCTCGAACAGGCGTTCGACGCGGCGTTCTAA

Protein sequence : 
MSEDERRIETRAIHAGQEPDEETGALMTPIYANSTYAQDGPGDHRGYEYSRTGNPTRTDLESNLAALENGSYGRAFSSGM
GAINTVLNLLEAGDHVVAGNDVYGGTHRIFTQVYEKYDLEFDFVETTDHDAVRDAVRDETALVWVETPTNPLMRVNDIEA
LADIAHEVDALCAVDNTFATPYLQRPLDLGADIVSHSLTKYLGGHSDIVGGALITDDEELDEEIAFYQNSVGATPSPFDC
FLVLRGAKTLPVRMDRHCDNARDLATWLDNHDAVETVHYPGLDSHPQHELAAEQMDDFGGMLSFELDGTLEQASTVVEET
EVFTLAESLGGVESLIEQPAAMTHAAIPREERLEAGLTDGLIRVSVGIEHIDDMKADLEQAFDAAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-84 51
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-83 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-66 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_006350425.1 cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) BAC0207 Protein 9e-67 43