Gene Information

Name : Theba_1276 (Theba_1276)
Accession : YP_006346207.1
Strain : Mesotoga prima MesG1.Ag.4.2
Genome accession: NC_017934
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1346419 - 1347615 bp
Length : 1197 bp
Strand : +
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase

DNA sequence :
ATGGATAAGACGAAGAAGCACCACTTTGATACCCTCTCGATTCACGCCGCAGAGCAAGAAGACCAAAATCAGTCTCTGAA
TCCGCCAATATACATGACCTCTACGTTTACATTTACTGACCTGCAGCAGGCGGAGGATACTTTTTCATTCAAACGACGTG
CCTACGTATACACACGAGGTGGGAACCCTACGATAAATCTTTTCGAACAGAGGCTGGCAACCCTGGAAAACGGTGTTGAC
GGGGTAGCCTTCTCTTCAGGCATGGCAGCCATAAGCTCAGTTGTCATGTCCTTTGCCGCCGCTGGGGATTCGTTGGTTGC
CCACAGGAATCTCTACGGCTCTACATTCGGTTTTCTAAATCACCTAATAACGAACTACGGGGTCAAGACGAAATTCATAA
ACATGACCGATCTTAACGCCGTAGAGAAAGCTATTACTTCGGAGACAAAGCTAATCTACCTTGAAACTCCTACCAATCCT
GCACTCGAGATAATCGACATAGAAGCACTCGCTAAGATCGCACATTCAAACGGTGTCAAGGTAGTTGTCGACAATACATT
TGCAACACCCGTCTTTCAACGACCGCTTGATTTCGGCGCGGATGTCGTGCTTCACAGCGCAACGAAGTACATATCCGGTC
ATGGAGACGTAATCGGCGGCTTTGCAACTTCAAAGGACTTCGACTACGTTCAAAAGCTCAAGTTTGGATACATGTGCGAA
CTGGGGGGAGTGATGAGTCCCTTCAACGCCTGGTTGTTGCTTAGAGGTATGAAGACATTGGGCCTTAGAATGGAGAGACA
CGAAAAAAACGCAAGGGAAATCGCAAACTTTCTGAGGAACCGCCCCGAAGTAGTGAAGGTATCTTATCCTGGCTTTGAAG
ATCATCCCGGACATGATATTGCATCGCGGCAGATGGAAGGATTTGGAGGTATCATAAGCTTCGAATTGAAGGGTCCAAGA
GAGAACGCTGAAAGCTTCGTGAGAAATCTGAACCTAATCAAACTCGCGGTATCTCTCGGTGATGCCGAGACACTGGTGGA
AGTGCCAGCGATGATGACTCACAGAGATTATCCGGAAGAAGAGCTGCACGAATTCGGCTTTTCAAGCAAGACTGTACGAA
TTTCTGCTGGACTTGAGCATTACTCGGATTTACTCAATGATATCGAAAATTCTCTCGACAAGGTTTACAGACAATGA

Protein sequence :
MDKTKKHHFDTLSIHAAEQEDQNQSLNPPIYMTSTFTFTDLQQAEDTFSFKRRAYVYTRGGNPTINLFEQRLATLENGVD
GVAFSSGMAAISSVVMSFAAAGDSLVAHRNLYGSTFGFLNHLITNYGVKTKFINMTDLNAVEKAITSETKLIYLETPTNP
ALEIIDIEALAKIAHSNGVKVVVDNTFATPVFQRPLDFGADVVLHSATKYISGHGDVIGGFATSKDFDYVQKLKFGYMCE
LGGVMSPFNAWLLLRGMKTLGLRMERHEKNAREIANFLRNRPEVVKVSYPGFEDHPGHDIASRQMEGFGGIISFELKGPR
ENAESFVRNLNLIKLAVSLGDAETLVEVPAMMTHRDYPEEELHEFGFSSKTVRISAGLEHYSDLLNDIENSLDKVYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-63 42
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-62 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theba_1276 YP_006346207.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 3e-80 45