Gene Information

Name : topB (ES15_2311)
Accession : YP_006343395.1
Strain : Cronobacter sakazakii ES15
Genome accession: NC_017933
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2471508 - 2473454 bp
Length : 1947 bp
Strand : -
Note : COG0550;K03169

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAGCCCAGTCTGGGGCGCGCCATCGCCGACGTGTTGCCGAAACCGCACCGCCGGGGCGA
CGGGTTTATTGAGTGCGGGAACGGCCAGGTGGTCACCTGGTGCGTCGGGCATCTGCTGGAGCAGGCGCAGCCGGACGCCT
ATGACAGCCGCTATGGCCGCTGGAATCTCGCCGACTTACCCATCGTGCCGGAAAAGTGGCAGCTCCAGCCGAAACCGTCG
GTTGCAAAGCAGCTTAATGTGATTAAAAAGCTGCTGCGCGAGGCGCAGGAGATTGTTCACGCAGGCGACCCGGACCGCGA
AGGGCAACTGCTGGTGGATGAAGTGCTCGACTACCTGCAACTGCCCGCGGAAAAGCGCCAGCAGGTGCGCCGCTGCCTGA
TTAACGATCTCAACCCGCAGGCGGTGGAGCGCGCTATCGATAAACTGCGCGAGAACCGCGAGTTTGTGCCGCTCAGCACC
TCGGCGCTCGCCCGCGCCCGCGCGGACTGGCTTTACGGCATTAACATGACGCGCGCTTATACGCTGCTCGGGCAGAACGC
GGGCTACCAGGGCGTGCTTTCGGTAGGCCGCGTCCAGACGCCCGTGCTGGGGCTGGTGGTGCGGCGCGACGAAGAGATTG
AAAACTTTGTCGCCAAAGATTTCTTTGAGGTCAAAGCGCACATCGTCACGCCCGCGCAGGAGCGCTTTACCGCGCTCTGG
CAGCCGAGCGAGGCCTGCGAGCCGTACCAGGATGAAGAGGGGCGGCTCCTCAACCGCGCGCTGGCGGAGCATGTCGTTAA
GCGTATAGAAGGGCAGCCAGCGGTTGTCACCAGCTATAACGACAAGCGCGAAAGCGAGGCCGCGCCGCTGCCGTTCTCTC
TCTCGACGCTGCAAATCGAGGCCGCCAGACGCTTCAACCTGAGCGCGCAGACGGTGCTGGATATCTGCCAGAAGCTGTAC
GAAACCCACAAACTCATTACGTACCCGCGCTCCGACTGCCGCTATCTGCCGGAAGAACATTTCGCGGGCCGTCATGCGGT
GCTGAAGGCGATTGGCGTTCACGCGCCGGATCTCCTGCCGCAGCCCGCGGTCGATCCGGAGCGCCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGACGCGCACCACGCCATTATCCCGACCGCCCGCAGCGCGCCCGCGTCGCTCTCTGACGGCGAGGCG
AAAATCTACGGGCTTATTGCCCGTCAGTACCTGATGCAGTTCTGCCAGGACGCGCAGTTCCGCAAATGCGTAATTGAGCT
TGAAATCGCGGGCGGCAAATTCATCGCCAAAGCGCGCTTTCTGGCGGAGACGGGCTGGCGCGCGCTGCTTGGCGCGAAAG
AGCGTGACGAAGAGAACGACGGTACGCCGCTGCCGGTGGTGGCAAAAGGCGACGAGCTGCACTGCGAGCGTGGCGAAGTG
GTTGAACGCCAGACCCAGCCGCCGCGCCACTTTACCGACGCCACGCTGCTCTCGGCCATGACCGGCATCGCGCGTTTCGT
GCAGGATAAAGATCTGAAGAAGATCCTGCGCGCCACCGACGGGCTTGGCACCGAGGCGACCCGCGCGGGCATTATCGAGC
TTTTATTTAAGCGCGGTTTTCTTGAAAAGCAGGGGCGCTATATTCATTCGACGCCCGCCGGGAAAGCGCTTATCCACGCG
CTGCCGGAGCTTGCCGCGCGCCCGGACATGACCGCGCAGTGGGAATCGACGCTGACGCAAATTAGCGAGAAACAGTGCCG
CTATCAGGATTTCATGCAGCCGCTGGTGCAGACGCTCTACTCGCTGATTGATCAGGCGCGCAGCGCCCCGGTGCGTCAGT
TCCGCGGTCTGGTGGCGCCCCAGCAGGCGCAAAAACGCCGCGCGGGCAAGGGCGGTAAAAAGCCGGCGTCCCGCAAGCGC
GGCAGTGCCCAGCCTGCGGCGGAGTAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIECGNGQVVTWCVGHLLEQAQPDAYDSRYGRWNLADLPIVPEKWQLQPKPS
VAKQLNVIKKLLREAQEIVHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDKLRENREFVPLST
SALARARADWLYGINMTRAYTLLGQNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPAQERFTALW
QPSEACEPYQDEEGRLLNRALAEHVVKRIEGQPAVVTSYNDKRESEAAPLPFSLSTLQIEAARRFNLSAQTVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVLKAIGVHAPDLLPQPAVDPERRNRCWDDKKVDAHHAIIPTARSAPASLSDGEA
KIYGLIARQYLMQFCQDAQFRKCVIELEIAGGKFIAKARFLAETGWRALLGAKERDEENDGTPLPVVAKGDELHCERGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKQGRYIHSTPAGKALIHA
LPELAARPDMTAQWESTLTQISEKQCRYQDFMQPLVQTLYSLIDQARSAPVRQFRGLVAPQQAQKRRAGKGGKKPASRKR
GSAQPAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-109 41
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-109 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-109 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 8e-102 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-103 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 4e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-111 41