Gene Information

Name : aadK (MUS_0709)
Accession : YP_006327498.1
Strain : Bacillus amyloliquefaciens Y2
Genome accession: NC_017912
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 692861 - 693730 bp
Length : 870 bp
Strand : +
Note : -

DNA sequence :
GTGAGAAGTGAAGACGAAATGATGAAATTGATTCTTGATATTGCGATGAAGGACGAGAGAATCCGTCTTGTCACTTTAGA
GGGATCAAGAACCAATAAAAATGTACCGAGAGACAAATTTCAAGACTATGATATTTCTTATTTTGTGACCGATATGGACT
CCTTCACATCTGACGAAAGCTGGCTGGATCAGTTTGGCGAAAGAATGATGATGCAAAAACCTGAAGATATGGAACTTTTC
CCTCCGGAACTCGGAGACTGGTTCTCCTATCTAATGCTATTTAAAGATCATCATAAAATCGACTTAACTTTGATCCCTCT
GGGTCAAACAGAGGATTATTTTACACGGGGTGATGGTTTGGCGGAAATAGTATTAGACAAAGATGACCGAATCAACCATA
AGATTATTGCGAGTGATGAACAATATCATATAAAGAAACCGACTCCCCGAGAGTTTGATGATTGCTGTAATGAATTTTGG
ATGGTTTCAACCTATGTGATTAAAGGATTAATGCGTAAAGAAATACTGTTTGCGCTGGATCATATGAATGACATTCTAAG
GCCTAATGTTTTGCGTATGATTGCGTGGAATATCGGGATAGAGAATCAGTTTTCATTAAGTGTAGGGAAGAATTATAAGT
ATATTCAACATTACATGAATGCGAAAGATTGGGAAATCCTGCTGAATACTTATGTCGGCAATACTTATGAAAGCGTGTGG
AAGGCATTGTTTGACTGCCAGGGTCTCTTCAGAGCATATTCAAAGTCAGTGGCTGTTTTATTGAGATATGAATATCCTGA
ATATGATCAACAAATTACGGAATATACATTGAAACATTATCAGCGCTTTCAATCAGATTTTTCATTATGA

Protein sequence :
MRSEDEMMKLILDIAMKDERIRLVTLEGSRTNKNVPRDKFQDYDISYFVTDMDSFTSDESWLDQFGERMMMQKPEDMELF
PPELGDWFSYLMLFKDHHKIDLTLIPLGQTEDYFTRGDGLAEIVLDKDDRINHKIIASDEQYHIKKPTPREFDDCCNEFW
MVSTYVIKGLMRKEILFALDHMNDILRPNVLRMIAWNIGIENQFSLSVGKNYKYIQHYMNAKDWEILLNTYVGNTYESVW
KALFDCQGLFRAYSKSVAVLLRYEYPEYDQQITEYTLKHYQRFQSDFSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 6e-87 59
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 6e-87 59
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 3e-85 58
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 6e-60 57
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 9e-78 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadK YP_006327498.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 5e-79 59
aadK YP_006327498.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 3e-76 54
aadK YP_006327498.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 4e-61 54