Gene Information

Name : cadA_1 (PflA506_5106)
Accession : YP_006326494.1
Strain : Pseudomonas fluorescens A506
Genome accession: NC_017911
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 5599726 - 5602026 bp
Length : 2301 bp
Strand : -
Note : identified by similarity to GB:AAK48831.1; match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525

DNA sequence :
ATGAGCCACTCCATTCATACCCCGCACAAGCACGACCACAAGCATGATCACGATCACGATCACGATCACGATCACGGTCA
TGATCACAAACATGACCATGGGCCCGCCAAACTCACGCCTGTGGATAACCACGGCCATTCCGGCTCCTGCTGCTCCGGCG
CTGCCGGGCCTGCCATCGTGACCCTGAGCGAGGCGCCCACCGCCGGCTCGCGCCTGAGCACCTTCCGCATCGAAGCCATG
GACTGCCCTACCGAGCAGACGCTGATCCAGAACAAGCTGGGCAAGCTCGCTGGCGTGCAGCAACTGGAATTCAACCTGAT
CAACCGCATCCTCGGCGTCACCCATGACCTGCCGAACACCGCGCCGATCATTGAGGCAATCAAGTCCATCGGCATGCAGG
CCGACCCTATCGAAGAAGGCAGCCCTGCCGCCGCGCCGCCCGCCAAGAAACATTGGTGGCCGCTGGCGGTGTCGGGCGTG
GGTGCCCTGGGGGCCGAGGTGCTGCACTTCACTGGTGTGGCGCCCACCTGGGTAATCGCGCTGGTGGCGTTGGTGTCGAT
TCTCAGCGGCGGCCTTACCACCTACAAGAAGGGCTGGATTGCCCTGAAGAACTTCAACCTCAATATCAATGCCTTGATGA
GCATCGCGGTGACGGGCGCGATCCTGATTGGCCAGTGGCCCGAAGCGGCGATGGTGATGTTCCTGTTCACCGTGGCCGAG
TTGATCGAGGCCAAGTCCCTGGACCGTGCGCGCAACGCCATCAGCGGCCTGATGCAGATGACTCCGGAACAGGCCACGGT
GCGCCAGGCTGACGGTTCCTGGCTGGAACAAGAGGTCAAGAGCATTGATCTTGGGGCGATTGTGCGGGTAAAGCCTGGCG
AGCGCATCGGGCTCGACGGGGAAGTCACGGCCGGCCAGTCCACCATCGACCAGGCACCGATCACCGGGGAAAGCCTGCCG
ATAGAAAAAACCGTGGGCGATAAAGTGTTTGCCGGCACCATCAACCAGGCCGGCGCCCTGGAGTACAAGGTCACCGCCGC
GGCCAACAACTCCACGCTGGCGCGGATCATTCACGCCGTGGAACAGGCCCAAGGGGCACGGGCGCCAACCCAGCGCTTTG
TTGACAGTTTCTCCAAGGTCTACACCCCGGCTGTCTTCCTGTTTGCCCTCGGTGTGGCGGTGATTCCGCCGCTGTTCATG
GCGGGCGTGTGGTTTGACTGGATCTACCGCGCCCTCGTGCTGCTGGTGGTGGCCTGCCCTTGTGCCTTGGTGATCTCCAC
CCCGGTGACCATTGTCAGCGGCCTGGCGGCAGCGGCGCGCAAAGGCATCCTGATCAAGGGCGGCGTGTACCTGGAGGGCG
GCTACAAGCTCGACTACCTGGCCCTCGACAAGACCGGCACCATCACCCACGGCAAACCGGTGCAAACCGACTACCTGCCG
CTGTTCCCGAACATCGAAGACAGCGCGCCGGCCCTGGCGGCCAGCTTGGCATCGCGCTCCGATCACCCGGTGTCCCTGGC
GATTGCCAACGCAGCTGTGGATAAAAACCTGTCGACTCACGCTGTGGATAACTTCGAAGCCCTGGCCGGGCGCGGTGTGC
GGGGTGATATCAACGGCCAGACCTATCACCTGGGTAACCACCGCCTGGTGGAAGACCTGGGCTTGTGCTCAGAGGCGTTG
GAAGAAAAACTCTTCGCCCTGGAAAAACAAGGCAAGTCCGTGGTGTTGCTGTTGGACAAGTCTGGCCCGCTGGCGCTGTT
TGCCGTGGCCGACACGGTCAAGGAGAGCAGCCGCGAAGCTATTCAGCAGTTGCACGACCTGGGCATCAAGACCCTGATGC
TCACCGGCGACAACACCCACACTGCCAAGGCCATTGCGGCCCAGGTGGGTATCGACAAGGCCCAGGGCGACCTGTTGCCC
ACCGACAAACTGCAAGCCATCGAAACCCTATACGGCCAGGGCCGTCGGGTGGGCATGGTCGGTGACGGTATCAACGACGC
CCCGGCCCTGGCCCGTGCCGAGATCGGCTTCGCCATGGCCGCGGCGGGCACCGACACCGCTATCGAGACCGCCGACGTGG
CGCTGATGGACGATGATTTGCGCAAGATTCCGGCTTTCATTCGGTTGTCGCGGCAAACGTCGAGTATCCTCAAGCAGAAC
ATCGCCCTGGCGCTGGTGATCAAGGCGATCTTCCTGGCCGTCACGTTCATGGGCATGGCGACCATGTGGATGGCGGTCTT
CGCCGACATGGGCGTGAGCCTGCTCGTGGTGTTCAATGGCCTGCGCCTGGTGCGCAAATAG

Protein sequence :
MSHSIHTPHKHDHKHDHDHDHDHDHGHDHKHDHGPAKLTPVDNHGHSGSCCSGAAGPAIVTLSEAPTAGSRLSTFRIEAM
DCPTEQTLIQNKLGKLAGVQQLEFNLINRILGVTHDLPNTAPIIEAIKSIGMQADPIEEGSPAAAPPAKKHWWPLAVSGV
GALGAEVLHFTGVAPTWVIALVALVSILSGGLTTYKKGWIALKNFNLNINALMSIAVTGAILIGQWPEAAMVMFLFTVAE
LIEAKSLDRARNAISGLMQMTPEQATVRQADGSWLEQEVKSIDLGAIVRVKPGERIGLDGEVTAGQSTIDQAPITGESLP
IEKTVGDKVFAGTINQAGALEYKVTAAANNSTLARIIHAVEQAQGARAPTQRFVDSFSKVYTPAVFLFALGVAVIPPLFM
AGVWFDWIYRALVLLVVACPCALVISTPVTIVSGLAAAARKGILIKGGVYLEGGYKLDYLALDKTGTITHGKPVQTDYLP
LFPNIEDSAPALAASLASRSDHPVSLAIANAAVDKNLSTHAVDNFEALAGRGVRGDINGQTYHLGNHRLVEDLGLCSEAL
EEKLFALEKQGKSVVLLLDKSGPLALFAVADTVKESSREAIQQLHDLGIKTLMLTGDNTHTAKAIAAQVGIDKAQGDLLP
TDKLQAIETLYGQGRRVGMVGDGINDAPALARAEIGFAMAAAGTDTAIETADVALMDDDLRKIPAFIRLSRQTSSILKQN
IALALVIKAIFLAVTFMGMATMWMAVFADMGVSLLVVFNGLRLVRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-114 47
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-115 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-115 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA_1 YP_006326494.1 cadmium-translocating P-type ATPase BAC0298 Protein 0.0 66