Gene Information

Name : megL (PflA506_2292)
Accession : YP_006323775.1
Strain : Pseudomonas fluorescens A506
Genome accession: NC_017911
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.11
Position : 2482323 - 2483567 bp
Length : 1245 bp
Strand : -
Note : identified by similarity to SP:P13254; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF06838; match to protein family HMM TIGR01328

DNA sequence :
ATGCACACTCAACACACCAGCTTCGGCTTTTGCACCCGTGCCATTCACCATGGCTATGACCCTGTTGACCATCACGGCGC
CCTCGTTCCGCCCATCTACTTGTCTGCCACCTTCGCCTTCCCCACCGTCGAATACGGCGCCGCCTGCTTTGCCGGAGAAG
CCAGCGGCCACTTCTATACGCGCATTTCCAACCCCACCCTGGCCCTGCTGGAGTCACGCATGGCCAGCCTGGAAAACGGC
GAGGCCGCCGTAGCATTCAGCTCCGGCATGGGCGCGATTGCCGCAACGTTCTGGACCCTGTTGCGCCCGGGCGACGAGAT
CATCGTCAGCCAGACCCTCTATGGCTGTACCTTCGCCCTGTTGCACCATGGCCTGGGCGAATTCGGTATCAAGGTGCGGC
ATGTCGACCTGACCGACCTGGCCGCCCTGCAAGCAGCATTCTCCCCGGCCACGCGCATGCTCTACTGCGAGACGCCGGCG
AACCCCAACCTGCGCCTGATCGACATCGCCGCCGTGGCCGAGTTGGCCCATCAACAGCCGAATGTCACCGTGGTGGTCGA
TAACACTTATTGCACGCCCTATCTGCAACGCCCCCTGGAACTGGGTGCCGATGTGGTGGTGCACTCGGCCACCAAATACC
TCAGCGGCCACGGCGACATCACCGCAGGTGTTGCGGTGAGCCACCAGGCGCTGGCACAGCGCATCCGCCTGCAAGGGCTC
AAGGACCTGACCGGCGCAGTGATGTCACCCCAGGACGCGTCGTTGCTGATGCGCGGCCTCAAGACCCTGGCCCTGCGCAT
GGACCGTCATTGCAGCAATGCCCAGGCGCTGGCCGAAGCCTTGCAGGCGCACCCGGCCGTGGAGAGTGTGATCTACCCCG
GGCTGCGTTCCTTCCCCCAGTACGAACTGGCGACCCGGCAAATGAAACTGCCCGGCGGCATGATTGCCTTTGAACTCAAG
GGTGGGATCGAGACGGGCCGGCGCTTTATGAACGCACTGCAACTGTTCACCCGTGCGGTCAGCCTGGGAGATGCCGAATC
ACTGGCCCAACACCCGGCGAGCATGACCCACTCCACCTACACCCCCGAGCAACTTGCGCAGCACGGTATCAGCGAGGGCC
TGGTGCGTTTGTCGGTGGGGCTTGAAGACGTTGCCGACCTGCTGACGGATATCCAACAGGCCCTGGCCAAGTGCAGCGGT
GCCAACCTGCGGCCAGCCCCCACAGCGGTTTATGCCATGAAATAG

Protein sequence :
MHTQHTSFGFCTRAIHHGYDPVDHHGALVPPIYLSATFAFPTVEYGAACFAGEASGHFYTRISNPTLALLESRMASLENG
EAAVAFSSGMGAIAATFWTLLRPGDEIIVSQTLYGCTFALLHHGLGEFGIKVRHVDLTDLAALQAAFSPATRMLYCETPA
NPNLRLIDIAAVAELAHQQPNVTVVVDNTYCTPYLQRPLELGADVVVHSATKYLSGHGDITAGVAVSHQALAQRIRLQGL
KDLTGAVMSPQDASLLMRGLKTLALRMDRHCSNAQALAEALQAHPAVESVIYPGLRSFPQYELATRQMKLPGGMIAFELK
GGIETGRRFMNALQLFTRAVSLGDAESLAQHPASMTHSTYTPEQLAQHGISEGLVRLSVGLEDVADLLTDIQQALAKCSG
ANLRPAPTAVYAMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-59 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-60 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-54 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_006323775.1 methionine gamma-lyase BAC0207 Protein 3e-148 75