Gene Information

Name : topB_1 (PflA506_2126)
Accession : YP_006323613.1
Strain : Pseudomonas fluorescens A506
Genome accession: NC_017911
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 2295020 - 2296969 bp
Length : 1950 bp
Strand : -
Note : identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056

DNA sequence :
ATGCGGCTGTACCTCTGTGAAAAACCCTCCCAGGCCAAGGATATCGCGGCTGTGCTTGGCGCCAGCCGCCGTGGCGATGG
GTGCTGGCTGGGTAATGGAGTCACGGTCACCTGGTGCATCGGCCACCTGCTGGAAACCGCCCCGCCCGACGCCTACGACG
CCAAATACAAACGCTGGGTGCTGGCCGACCTGCCGATCGTCCCGGAAAAATGGAAGATGCTGGTCAAGCCCAAGACCGCC
AGCCAATACAAGGCCGTCAAGCGCTTGCTGGGCGAAGCCCAGGAACTGGTGATCGCCACCGACGCCGACCGTGAAGGCGA
GATGATCGCCCGTGAACTGGTAGAACACTGCCGCTACCGCGGGCCGATCCAGCGGCTGTGGTTGTCGGCGCTCGACGACG
CCTCCATTCGCAAGGCCCTGGCGGCGCTCAAACCCGGTGCAGAAACCTTCAGCCTGTATCATTCGGCCCTGGGGCGCTCG
CGTGCGGACTGGCTGATCGGCATGAACATGAGCCGCCTGTTTACCCTGCTGGGGCGCCAATCCGGTTACCAGGGCGTGCT
GCCGGTAGGCCGCGTGCAAACCCCGACCCTGCGCCTGGTGGTGGACCGTGATCGCAGCATTGCCGACTTCGTGCCGGTGG
CCTATTGGGCCATTGATGTCGACCTGCGTCACGAGCACATGACCTTCACCGCCCAATGGCGCGCCCCTGACGATGCCTGT
GACGACCAGGACCGTTGCCTCAACCCGCAACTGGCGCGGGACGCCGCCGACGCCATGCTCAACGCCGCCACGGCGCGACT
GGTGAAACTGCGTACCGAGCGCATGCGCGAAGTGGCGCCCCTGCCCTTCGACCTCGGCACCTTGCAGGAGATCTGTTCGA
AGAAGCTCGGCCTGGGCGCCCAGGAAACCCTGGACATCGCTCAATCCCTGTACGAAACCCACAAGGCCATCACCTACCCG
CGCAGCGATTGCGGCTACCTGCCGTTGAGCCAGCACAGTGAAGCGCCGAAGATTCTTGCGGCGCTGGGCCGTGCGGACAC
GGCGGTCAACGAGCTGATGTCGCACATCGACCCTCGGCGCCGTTCGCGGGCCTGGAACGACGCGAAAGTCAGCGCCCACC
ACGGCATCATCCCCACCGGAGCCGGCAAGGAGGTCAGCCAACTGACCGGCAAGCACCGTGCGGTCTATACGCTGATTCGT
GCGCGCTACCTGGCGCAGTTCCTGCCCAACCATGAATACGACCGCACCCAGGCCGATTTGGACTGTGCCGGCCACGCGTT
GCGCGCGGTGGGCAAAGTCATCATCGAACCGGGCTGGAAACGCGCCTTGCCCGAAGCGCTGGCACCCGCCAAAGGTCGCG
AAGCCCCTGCGCCCCAAGCGTTGCCGACGCTGGTGCAGGGCCACGACTACGCCGTGGCCAAGGTCAACCTCAAGGACCTG
TGGACCCAGCCGCCCAAGCCCTTTACCGAAGGCGACCTGATCAAGGCCATGAAAAACGTCGCCAAGCTGGTGGAGGACCC
GTTGCTCAAGCAAAAACTCAAGGACACCACTGGCATCGGCACCGAGGCCACCCGCGCCGGGATCATCCAGGGCTTGCTGG
ACCGCGGTTATCTGGTGAAAAACGGCAAGGCCCTGTCGGCAACCCCGGCCGCGTTCAGCCTGATTGACGCAGTGCCCCGC
GCCATCGCCGACCCCGGCACCACCGCCATCTGGGAACAGGCGCTGGACATGGTGCAAAGCGGCGAAATGAGCCTGGAGGA
ATTCATCGCCAAGCAAGCGGCGTGGATGAGCAAGCAGGTGGCACGCTGTAACGGCATGCGCATGACTATCACTGGCCCCG
CCAGCCCGGCTGGACGAGGTGCAACGCCCTGGAAAAAGAAACGCAAGGCCGCCCCGCGCAAGGCCGGCGCCAGCCCCAAA
CGCGGGAAAAAGCCGGTAAATGCGGGATAG

Protein sequence :
MRLYLCEKPSQAKDIAAVLGASRRGDGCWLGNGVTVTWCIGHLLETAPPDAYDAKYKRWVLADLPIVPEKWKMLVKPKTA
SQYKAVKRLLGEAQELVIATDADREGEMIARELVEHCRYRGPIQRLWLSALDDASIRKALAALKPGAETFSLYHSALGRS
RADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVDLRHEHMTFTAQWRAPDDAC
DDQDRCLNPQLARDAADAMLNAATARLVKLRTERMREVAPLPFDLGTLQEICSKKLGLGAQETLDIAQSLYETHKAITYP
RSDCGYLPLSQHSEAPKILAALGRADTAVNELMSHIDPRRRSRAWNDAKVSAHHGIIPTGAGKEVSQLTGKHRAVYTLIR
ARYLAQFLPNHEYDRTQADLDCAGHALRAVGKVIIEPGWKRALPEALAPAKGREAPAPQALPTLVQGHDYAVAKVNLKDL
WTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPR
AIADPGTTAIWEQALDMVQSGEMSLEEFIAKQAAWMSKQVARCNGMRMTITGPASPAGRGATPWKKKRKAAPRKAGASPK
RGKKPVNAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 62
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 62
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 61
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-147 49
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-147 49
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 9e-148 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 3e-149 49
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-144 48
topB AAW83109.1 TopB Not tested GGI Protein 3e-112 43