Gene Information

Name : entE (EBL_c13920)
Accession : YP_006319005.1
Strain : Escherichia blattae DSM 4481
Genome accession: NC_017910
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1450958 - 1452568 bp
Length : 1611 bp
Strand : +
Note : (dihydroxybenzoic acid- activating enzyme) (enterobactin synthetase component E) (enterochelin synthase E)

DNA sequence :
ATGGCGATTGAATTTAACCACTGGCCGGAAGATTTAGCCCGGCACTACCGGGAAAAGGGCTACTGGGTGGATTTACCCCT
CGGCGATATTCTTGACCGTCACCAGCACAGTGAGGCCATTGCCCTGATTGACGGTACGCGCCAGTACCGTTACCGGGAGC
TGTATCAGCAGGTTAACCGCCTGGCGGGTGCCTTTCAGCGCCGGGGCTTAAAACGCGGGGACACGGCCCTGGTGCAACTG
GGCAATGTGGCGGAGCTGTGCATCACGCTGTTTGCCCTGCTGCGCATCGGGGTGGCCCCGGTGAATGCGCTGTTCAGCCA
TCAGCGTACCGAGCTGGATGCCTATGCCAGCCAGATTGAGCCCGCCCTGCTGGTGGCCGACCGGGAGCATAGCCTGTTTC
AGGATGAGCAATATATTGCGTCCCTGCACGCCCGTCTGCCCGGCTTAACAGTGGTGGCCCTGCTGCACGACACCGGTGAG
CGGGGACTGGAGTTCTGGATAGCCGAGCCGCTGGATCTCCCGCTGCAGGAGCCCAGCGCCCCCGGTGAAGTGGCCTTTTT
CCAGCTTTCCGGCGGCAGTACCGGCACGCCAAAACTGATCCCGCGCACTCACAATGACTACTACTACAGCATCCGGCGCA
GCGTGGAGATCTGTGGCTTTAACGGGCAGACCCGGTTTCTGTGCGCCATTCCCGCTGCCCACAATTACGCCATGAGCTCC
CCGGGCTGGCTGGGGGTGTTTTACGGTGGCGGCACGCTGGTGCTGGCCGCCGACCCCAGCCCGACGCTGTGCTTCGGGCT
GATTGCCCGGCAGCGCATTACCCACACGGCACTGGTGCCCCCGGCAGTCAGCCTGTGGCTCCAGGCGCTGCGCGATGGTG
TCGCGGGGGATTTATCAACCCTGCAGCTGTTGCAGGTGGGGGGCGCCCGCTTGTCTGAAGCGCTGGCGCGGCGGATCCCG
GCCGAGATCGGCTGCCAGCTCCAGCAGGTATTCGGCATGGCGGAAGGGCTGGTGAACTACACCCGGCTGGATGACAGCGA
CGAGGTGATTTTTACCACCCAGGGGCGCCCCATGTGCCCGGATGATGAAATCCGGGTGGTGGATGAACAGGGCACCCCGG
TGCCGCCGGGAACAGAAGGCCGCCTGATGACCCGCGGGCCTTATACCTTCCGGGGCTATTACCGCAGCCCGGAGCACAAT
GCCCGGGCCTTCGACCAGGACGGTTTTTACAGCTCCGGTGACCTGGTTATCCTCGGTGAGGACGGCAATATCCGGGTGGT
CGGGCGCGAAAAAGATCAGATAAACCGCGGCGGCGAGAAGATAGCCGCCGAGGAGATAGAAAACCTGCTGCTGCGCCATG
AGGCCATTTTGCATGTGGCGCTGGTCTCTATGGACGACGCGCTGATGGGGGAGAAGAGCTGCGCTTTTATTGTCGGTCAC
CGTCCGCTGCGCGCCGTGGAGATCCGCCGTTACCTGCGTGAGCTGGGGGTGGCGGAATTTAAACTGCCGGACCGTGTTGA
GATGGTCCCGTCACTGCCGCTGACCCCGGTCGGGAAAGTGGATAAGAAAAAACTGCGCCACATTATCGCGCAACGCCAGC
AGGCCCGGTAA

Protein sequence :
MAIEFNHWPEDLARHYREKGYWVDLPLGDILDRHQHSEAIALIDGTRQYRYRELYQQVNRLAGAFQRRGLKRGDTALVQL
GNVAELCITLFALLRIGVAPVNALFSHQRTELDAYASQIEPALLVADREHSLFQDEQYIASLHARLPGLTVVALLHDTGE
RGLEFWIAEPLDLPLQEPSAPGEVAFFQLSGGSTGTPKLIPRTHNDYYYSIRRSVEICGFNGQTRFLCAIPAAHNYAMSS
PGWLGVFYGGGTLVLAADPSPTLCFGLIARQRITHTALVPPAVSLWLQALRDGVAGDLSTLQLLQVGGARLSEALARRIP
AEIGCQLQQVFGMAEGLVNYTRLDDSDEVIFTTQGRPMCPDDEIRVVDEQGTPVPPGTEGRLMTRGPYTFRGYYRSPEHN
ARAFDQDGFYSSGDLVILGEDGNIRVVGREKDQINRGGEKIAAEEIENLLLRHEAILHVALVSMDDALMGEKSCAFIVGH
RPLRAVEIRRYLRELGVAEFKLPDRVEMVPSLPLTPVGKVDKKKLRHIIAQRQQAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-89 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-89 44
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-89 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-89 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-89 44
ybtE CAA21394.1 - Virulence HPI Protein 7e-89 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 7e-89 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-87 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-87 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_006319005.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 0.0 69
entE YP_006319005.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-110 46
entE YP_006319005.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 8e-84 42