Gene Information

Name : OOM_1068 (OOM_1068)
Accession : YP_006316989.1
Strain : Francisella noatunensis Toba 04
Genome accession: NC_017909
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 1066513 - 1068648 bp
Length : 2136 bp
Strand : +
Note : COG1982;OKR_DC_1;(PatternScan:IPR000310);Orn/Lys/Ar g decarboxylase, major region;Molecular Function: catalytic activity (GO:0003824);OKR_DC_1_N;(HMMPfam:IPR005308);Orn/Lys/Arg decarboxylase, N-terminal;Molecular Function: carboxy-lyase activity (GO:00168

DNA sequence :
ATGAAGACAATTGTATTTGTATATAAAGACACTTTAAAATCCTATAAAGAAAAGTTCTTACTAAAGATTGAAAAAGATTT
ACAAAGTTATGAATATCATACTTTAACAGTAGATGATTTATCTGAGGTTGTAGAGATTCTTGAGGATAATTCAAGAATAT
GTTGTATTGTGCTTGATAGAACTAGTTTTAGTATTGAAGCATTTCATAATATTGCTCATCTTAACACTAAACTACCAGTA
TTTGTGGTTTCTGATTATAGCCAAAGTATCAAACTTAATTTACGTGATTTTAATTTAAATATTAACTTTTTACAGTATGA
TGCTTTAGCTGGTGAGGATTCTGATTTTATTCATAGAACTATTACAAACTACTTCAATGATATTTTGCCACCTTTAACTT
ATGAGTTGTTTAAATATTCTAAATCGTTTAACTCATCATTCTGTACTCCAGGTCACCAAGGAGGCTACGGTTTTCAGCGT
TCGGCAGTAGGCGCATTATTCTATGATTTTTATGGCGAGAATATTTTTAAGACAGACTTATCTATTTCAATGAAAGAGCT
AGGAAGTTTATTAGATCATTCTGAGGCTCATAAAGATGCCGAAGAGTATGTCGCAAAAGTTTTCCAAGCTGATAGATCGT
TAATTGTTACTAACGGAACATCAACAGCTAATAAAATAGTAGGTATGTATAGTGTTGCCGATGGCGATACAATTCTTGTT
GATAGAAATTGCCATAAATCAGTTACACACCTAATGATGATGGTAGATGTTAATCCAATATATCTAAAACCAACAAGAAA
TGCTTATGGCATAATTGGTGGTATACCTAAAGAAGAATTTCAGCACCAAACTATCCAAGAAAAAATTGATAATAGTAGCA
TTGCAGATAAATGGCCTGAATATGCTGTTGTTACAAATTCAACTTATGATGGTATTTTATATAATACAGATACTATTCAT
CATGAACTAGATGTTAAAAAGTTACATTTTGATAGTGCTTGGATACCATACGCGATATTTCATCCAATCTATAAGCATAA
GTCTGCGATGCAGATTGAACCAAAGCCAGAGCATATAATCTTTGAGACACAATCCACTCACAAACTTTTAGCGGCCTTCA
GTCAGTCATCAATGTTGCACATAAAAGGTGATTATAACGATGAAGTTTTAAATGAAGCATATATGATGCATACTTCAACA
TCTCCTTTTTATCCAATAGTTGCTAGTGTTGAGACGGCAGCAGCAATGATGGAGGGTGAGCAGGGATATAATCTTATCGA
TAAAACTATTAATCTAGCGATAGATTTTAGACGAGAGCTAGTCAAGCTTAGATCAGAGGCTGGTGATTGGTTCTTTGATG
TTTGGCAACCTGATAATATTTCTAATAAAGAGGCGTGGTTATTAAGAAATGCTGATAAATGGCATGGATTTAAAAATATA
GATGGAGATTTTCTTTCATTAGACCCGATTAAGATAACAATCTTAACTCCAGGTATAAAAGATAATGATGTCCAAGATTG
GGGTGTACCAGCAGATATAGTAGCTAAGTTTTTAGATGAGCATGATATTGTAGTTGAGAAATCAGGACCTTATTCATTGT
TGTTTATCTTTAGTTTAGGCACTACAAAAGCAAAATCAGTAAGGCTAATATCGGTACTTAATAAATTCAAACAAATGTAT
GATGAAAATACATTAGTTGAGAAGATGCTACCAACATTATATGCTGAAGATCCTAAGTTCTATAAAGATATGAGAATCCA
AGAAGTTAGTGAAAGATTACACCAGTATATGAAAGAAGCTAATCTTCCTAATCTTATGTACCATGCCTTTAATGTGTTAC
CTGAACAGCAACTTAATCCTCATAGAGCTTTTCAGAAATTACTAAAAGGTAAAGTCAAAAAAGTCCCGTTAGCAGAGCTA
TATGGACAGACCTCAGCCGTGATGATATTACCATATCCACCAGGTATACCAGTGATATTCCCAGGCGAAAAAGTTACTGA
AGAATCTAAGGTAATATTAGATTTCTTATTGATGTTAGAGAAGATAGGATCAATGCTGCCAGGATTTGATACAGATATAC
ATGGACCAGAGAGAGCAAAAGATGGTAAATTATATATCAAAGTGATTGATGATTAA

Protein sequence :
MKTIVFVYKDTLKSYKEKFLLKIEKDLQSYEYHTLTVDDLSEVVEILEDNSRICCIVLDRTSFSIEAFHNIAHLNTKLPV
FVVSDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHRTITNYFNDILPPLTYELFKYSKSFNSSFCTPGHQGGYGFQR
SAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYVAKVFQADRSLIVTNGTSTANKIVGMYSVADGDTILV
DRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKEEFQHQTIQEKIDNSSIADKWPEYAVVTNSTYDGILYNTDTIH
HELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPKPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNDEVLNEAYMMHTST
SPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELVKLRSEAGDWFFDVWQPDNISNKEAWLLRNADKWHGFKNI
DGDFLSLDPIKITILTPGIKDNDVQDWGVPADIVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQMY
DENTLVEKMLPTLYAEDPKFYKDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLAEL
YGQTSAVMILPYPPGIPVIFPGEKVTEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 54
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 1e-170 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
OOM_1068 YP_006316989.1 lysine decarboxylase VFG1670 Protein 6e-171 50