Gene Information

Name : W7S_04405 (W7S_04405)
Accession : YP_006304591.1
Strain : Mycobacterium sp. MOTT36Y
Genome accession: NC_017904
Putative virulence/resistance : Virulence
Product : two-component response transcriptional regulatory protein PrrA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 875047 - 875757 bp
Length : 711 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
ATGGGCGGCATGGACACAGGAGCTAGCTCACCTCGGGTCTTGGTCGTCGACGACGACTCCGATGTGCTCGCGTCGCTGGA
ACGTGGCCTGCGCCTGTCCGGGTTCGAGGTGTCGACCGCGGTCGACGGCGCCGAGGCGTTGCGCAGCGCCACCGAAACGC
GGCCGGACGCGATCGTGCTCGACATCAACATGCCGGTGCTGGACGGGGTCAGCGTCGTCACCGCGCTGCGCGCCATGGAC
AACGACGTCCCGGTCTGCGTGCTCTCCGCCCGCAGCTCGGTCGACGACCGGGTGGCGGGCCTGGAGGCCGGCGCCGACGA
TTACCTGGTCAAACCGTTCGTGCTGGCCGAGCTGGTCGCGCGGGTCAAAGCGCTGCTGCGCCGCCGCGGCGCCACCGCCA
CCTCCTCGTCGGAGACCATCACGGTGGGACCGCTGGAAGTCGACATCCCCGGCCGGCGGGCTCGCGTCAACGGCGTCGAC
GTCGACCTGACCAAGCGGGAATTCGACCTGCTGGCGGTGCTGGCCGAACACAAGACCGCGGTCCTGTCCCGTGCGCAGCT
ACTCGAGCTGGTATGGGGCTATGACTTTGCCGCCGACACCAACGTCGTCGACGTCTTCATCGGATACCTGCGCCGCAAGC
TCGAGGCCCACGGCGGGCCCCGGCTGCTGCACACCGTGCGCGGAGTGGGATTCGTGCTGCGCATGCAGTAA

Protein sequence :
MGGMDTGASSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVVTALRAMD
NDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGPLEVDIPGRRARVNGVD
VDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAHGGPRLLHTVRGVGFVLRMQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-25 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-24 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0083 Protein 2e-30 45
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0125 Protein 5e-30 44
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0197 Protein 3e-24 44
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA AE000516.2.gene3505. Protein 7e-29 44
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0638 Protein 1e-23 43
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_012469.1.7685629. Protein 1e-26 43
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA HE999704.1.gene1528. Protein 1e-30 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_002952.2859905.p0 Protein 6e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_003923.1003749.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_002758.1121668.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_007622.3794472.p0 Protein 6e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_009641.5332272.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_013450.8614421.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_007793.3914279.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_002745.1124361.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_009782.5559369.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_002951.3237708.p0 Protein 9e-27 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA HE999704.1.gene2815. Protein 3e-26 42
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0308 Protein 2e-27 41
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0347 Protein 2e-23 41
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA BAC0111 Protein 1e-25 41
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA NC_012469.1.7686381. Protein 2e-22 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA VFG1389 Protein 4e-83 98
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA VFG1390 Protein 5e-41 50
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA VFG1386 Protein 4e-36 46
W7S_04405 YP_006304591.1 two-component response transcriptional regulatory protein PrrA VFG0596 Protein 1e-25 42