Gene Information

Name : W7S_02290 (W7S_02290)
Accession : YP_006304168.1
Strain : Mycobacterium sp. MOTT36Y
Genome accession: NC_017904
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit ClpC1
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 464987 - 467530 bp
Length : 2544 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTTGAAAGATTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCGCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGTTTGATTCACGAGGGCGAAGGCGTCGCGGCGAAGTCGCTGGAGTCGCTGGGCA
TCTCGCTCGAGGGCGTTCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCGGGCCACATCCCGTTC
ACCCCGCGCGCCAAGAAGGTTCTCGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTGGGCCTGATCCGTGAGGGTGAGGGCGTGGCCGCGCAGGTGCTGGTGAAGCTGGGCGCGGAGCTGACCCGGG
TGCGCCAGCAGGTCATCCAGCTGCTGAGTGGCTACCAGGGCAAGGAGGCCGCCGAGGCGGGCACCGGTGGCCGCGGTGGC
GAGTCCGGCAGCCCCTCGACGTCGTTGGTGCTCGACCAGTTCGGCCGCAACCTGACGGCCGCCGCGATGGAAGGCAAGCT
GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTGATGCAGGTGCTGAGCCGGCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACGGCCGTCGTCGAGGGCCTGGCGCAGGCCATCGTGCACGGCGAGGTCCCGGAG
ACACTCAAGGACAAGCAGCTCTACACGCTGGACCTGGGCTCGCTGGTCGCGGGCTCGCGCTACCGCGGTGACTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACCCTGGTGG
GTGCGGGCGCCGCCGAGGGCGCGATCGACGCCGCGTCGATCCTCAAGCCCAAGCTGGCCCGCGGCGAGCTGCAGACGATC
GGCGCCACCACGCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGCCGCTTCCAGCCGGTGCAGGT
CGGGGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGCCTGCGCGACCGCTACGAGGCGCACCACCGGGTCTCGA
TCACCGACCCGGCGCTGGTCGCGGCGGCCACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCGGGCGCCCGGATGCGGATCCGCCGGATGACCGCGCCGCCAGACCTGCGCGAGTTCGACGAGAA
GATCGCCGACGCGCGCCGGGAGAAGGAATCGGCGATCGACGCCCAGGACTTCGAGAAGGCGGCCAGCCTGCGGGATCGGG
AGAAGCAGCTGGTGGCCCAGCGCGCCGAGCGCGAAAAGCAGTGGCGCTCCGGCGATCTCGACGTGGTCGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACGGGCATCCCGGTGTTCAAGCTCACCGAGGCCGAGACCACGCGGTT
GCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCCGTCTCCAAGGCGATCCGCC
GCACCCGCGCCGGGCTGAAAGACCCCAAGCGCCCGTCGGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGGTTCACCGCGTCGCGGTTGTTCGGCGCCCCGCCGGGATACGTCGGCTATGAGGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGCAAGCCGTTCTCCGTGGTGCTGTTCGACGAGATCGAGAAGGCGCACCAGGAGATCTACAACAGCCTGCTGCAG
GTCCTCGAGGACGGTCGGCTCACCGACGGTCAGGGACGCACGGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTCGGCACGTCCGACATCTCCAAGCCGGTCGGCCTGGGCTTCACCCAGGGTGGCGGTGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACCCGCGACGAGATCATCCGGATGGTCGATCTGATGATCCAGCGCGTCGGCAACCAGCTCAAGAGCAAGGACAT
GGCGATGGAGCTGACCGACAAGGCCAAGGCATTGCTGGCCAAGCGCGGCTTCGACCCCGTGCTGGGTGCCCGTCCGCTGC
GGCGCACCATCCAGCGCGAGATCGAGGACCAGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGTCCCGGCCAGGTTGTC
ACGGTCGACGTCGACAACTGGGACGGCGAGAGCGCCGGCGAGGACGCGAAGTTCACCTTCACCGGCACCCGCAAGCCGCC
GGCCGAGCCGGACCTGGCCAAGGCCGGGGCGCACGCCGCGCCGCAGGGGCCGGACCCGCAGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDPALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTRDEIIRMVDLMIQRVGNQLKSKDMAMELTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVV
TVDVDNWDGESAGEDAKFTFTGTRKPPAEPDLAKAGAHAAPQGPDPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
W7S_02290 YP_006304168.1 ATP-dependent protease ATP-binding subunit ClpC1 VFG0079 Protein 0.0 60
W7S_02290 YP_006304168.1 ATP-dependent protease ATP-binding subunit ClpC1 VFG0080 Protein 9e-149 51