Gene Information

Name : W7S_09330 (W7S_09330)
Accession : YP_006305568.1
Strain : Mycobacterium sp. MOTT36Y
Genome accession: NC_017904
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1999339 - 2000976 bp
Length : 1638 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGACCCCGAACACAACGCCGCCGGCCGGAGTCCTCGACGGGTTCGTGCCCTTCCCCGCTGATCGCGCCGCCGCCTACCG
GGCGGCCGGCTATTGGGCGGGACGGACGCTGGACACGATCCTGACCGACGCGGCCCGGCAGTGGCCCGATCGAACCGCGG
TGCGCGACGCCGTGGCCGGTACCGGCTTCAGTTATGCGGACCTCGACGACCAGGCTAACCGCGCCTCCGGCGGGCTGCGG
GCACTGGGTATCGCGCCGGGCGACCGGGTGCTGCTGCAGTTGCCGAACAGCTGCCAGTTCGCGGTGGCCTTGTTCGGGTT
GCTGCGGGCGGGGGCGGTCCCGGTGATGTGCCTGCCGGGACACCGGGCCGCCGAGCTTGGGCATTTCGCCGCGGTCAGCG
CGGCCACCGGTCTGTTGATCGCCGATACCGCGGCGGGTTTCGACTATCGCACGATGGCGCTCGGCCTCATCGAGGAACAC
CCAACGCTGCGGCACGTCATCGTCGACGGCGACCCGGGGCCGTTCACCTCGTGGGCGCAGTTGTGCGAGCGGGCGCCCGG
CCCGCCGTCCTCGGCTGACCCGGGATCGCCTGCGCTGCTTCTGGTTTCCGGCGGGACCACGGGCACACCCAAGCTCATCC
CCCGCACCCACGACGATTACGTGTTCAACGCGACGGCCAGCGCCGAACTCTGCCGGCTCACCTGCGATGACGTCTATCTG
GCTGTGCTGTCGGCCGGACACAATTTTCCCCTCGCCTGTCCCGGCCTGCTCGGCGCGATGACGGTGGGCGCCACCACCGT
CTTCGGCACCGATCCCAGCCCCGAGGCGGCCTTCGCCGCCATCGACCGCCATGGCGTCACGGTCACCGCCCTGGTGCCGG
CCCTGGCCAAACTGTGGGCGCAGGCCTGCGAGTGGGAAACGGTGACTCCAAAAACCTTGCGGCTCTTACAAGTCGGTGGC
GCCAAGCTGGAGCCCGAGGACGCCCGCCTGGTGCGCACCGCCTTGACGCCGGGCCTGCAGCAGGTGTTCGGGATGGCCGA
GGGGCTGCTGAACTACACGCGCCCCGACGATCCGCCCGAAGTCACCGAGCACACGCAGGGCCGGCCGTTGTCCGCCGCCG
ACGAACTGCGCGTCGTCAATGCGGCGGGCGAGCCCGTGCCCCCCGGCGAGGAAGGCGAATTGCTGGTCCGCGGACCCTAC
ACGTTCAACGGCTACTTTCGCGCCGAGCGCGACAACGAGCGCTGCTTTGACGCGCAAGGCTTCTTCCGCAGCGGTGATCT
GGTCCGGATCACCGACGACGGCTACGTCGTGGTCACCGGCCGCGTCAAAGACGTCATCTGCCGCGGCGGCGAAACCATCT
CCGCGGCGGACCTCGAGGAGCAGATGCACAGCCACCCGGCGATCTTCTCGGCGGCCGCGGTGGCGCTCCCCGACCCTTAT
CTGGGCGAGAAGATCTGTGCGGCAATCGTTTTCGACGGCCCTGAGCTATCGCTCGCGGAGCTTAACGGCTACCTCGACGG
GCGTGGCGTGGCCGCGCACGCGCGTCCCGACGTCTTGGTTCCGATGACCACGCTGCCCACCACGCCGATCGGCAAGATCG
ACAAAAAGGCGATCGCCGGCCAGATTTCGGCGCGCTAG

Protein sequence : 
MTPNTTPPAGVLDGFVPFPADRAAAYRAAGYWAGRTLDTILTDAARQWPDRTAVRDAVAGTGFSYADLDDQANRASGGLR
ALGIAPGDRVLLQLPNSCQFAVALFGLLRAGAVPVMCLPGHRAAELGHFAAVSAATGLLIADTAAGFDYRTMALGLIEEH
PTLRHVIVDGDPGPFTSWAQLCERAPGPPSSADPGSPALLLVSGGTTGTPKLIPRTHDDYVFNATASAELCRLTCDDVYL
AVLSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFAAIDRHGVTVTALVPALAKLWAQACEWETVTPKTLRLLQVGG
AKLEPEDARLVRTALTPGLQQVFGMAEGLLNYTRPDDPPEVTEHTQGRPLSAADELRVVNAAGEPVPPGEEGELLVRGPY
TFNGYFRAERDNERCFDAQGFFRSGDLVRITDDGYVVVTGRVKDVICRGGETISAADLEEQMHSHPAIFSAAAVALPDPY
LGEKICAAIVFDGPELSLAELNGYLDGRGVAAHARPDVLVPMTTLPTTPIGKIDKKAIAGQISAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-82 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-82 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-82 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 7e-82 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-82 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-82 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-82 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-82 42
ybtE CAA21394.1 - Virulence HPI Protein 7e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
W7S_09330 YP_006305568.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-177 78
W7S_09330 YP_006305568.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-79 45
W7S_09330 YP_006305568.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 4e-69 41