Gene Information

Name : D7S_00602 (D7S_00602)
Accession : YP_006286265.1
Strain : Aggregatibacter actinomycetemcomitans D7S-1
Genome accession: NC_017846
Putative virulence/resistance : Virulence
Product : hemolysin D
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 593871 - 595304 bp
Length : 1434 bp
Strand : -
Note : -

DNA sequence :
ATGAAAACTTGGCTTTTGGCATTGTATGATGTGCTTTCCCGTTATAAAAACGTGTGGAATGAAACTTGGAAAATTCGTAA
ACAGCTTGATTCTCCGGTTAGAGAAAAAGATGAAAATGAATTTCTGCCCGCGCATTTGGAATTAATTGAAACACCTGTAT
CAAATGCACCACGATTCGTGTCTTATTCCATTATGCTCTTTTTAACTTTAGCGATTATTGTTTCTATTTTTAGCAATGTG
GAAATTATCGCAACGGCTTCAGGAAAATTCGCACTAAGCGGGAGAAGCAAAGAAATTAAACCGATTGAAAACTCATTGGT
TAAAGATATTTTTGTGAAAGAGGGCGAATACGTGAAAAAGGGTGAACTATTGTTAAAACTGACCGCACTTGGTGCCGAAG
CGGATACGTTAAAAACGAAGACATCGCTTTCTCAGGCTAAACTGGAGGAATTTCGTTATAAATCTTTATTGGAAGCTGTT
GAAAAAGATCAATTACCAATATTAGATTTTTCTAAAATTGATTTGCCTTTTATGACGGAAAACGATCAAAAAAGAGTGAC
TTTACTGATTGAAGAACAATTCTCTACTTGGCAAAAACAACGCCATCAGAAAACCTTGAATCTTAATAAAAAAGAAGCGG
AAAAACTCAGTTATTTGGCACGAATAAAAAAATATGAAGGTCTGATTAATACAGAGCAAGTCCGATTGGATGATTTTAGA
GCCTTATATAAGGAACATGCTATTGCAAAACATACAGTTTTAGATGAAGAGAATAAATATCAGGATGCAATCAATGAGCT
TGAGGTATATAAGGCGAGTTTAATGCAAGTTGAAAACGAAGTTTTATTGGCCAAGGAAGAGCAGGAATTAGTCACACAAT
TGTTCAAAAATGATATTTTAGACAAGCTAAAACAGGCGACGGATAATGTGAATTTATTGACATTCGAACTAGACAAAAAC
AATCAACGCCAGCAAGTCTCTGAAATTCGAGCTCCTGTATCAGGTACTGTACAACAATTAAAAGTTCACACAATAGATGG
CGTTGTTACTACGGCTGAAACATTAATGGTAGTTGTGCCGGAAGAAGATTCCCTTGAAGTCACCGCACTTATTCAAAATA
AAGATATTGGTTTTGTGAAAGAAGGGCAAGAGGTTGTAATTAAGGTCGAAGCCTTCCCCTATACCCGTTATGGTTATTTA
ACGGGAAAAGTGAAAAATATTACTTTAGATGCGATTGAACATCCAAAGCTTGGACTTGTATTTAATACGATTATTGAACT
GGATAAAAAAACACTTTCTGCCGAAGAAAAAGAAATCCCACTTTCCGCAGGGATGGAAATTACTGCAGAAATTAAGACAG
GCATGAGAAGCGTTATAAGCTATCTACTTAGCCCATTAGAAGAATCTATTGATAAAAGTTTAAGAGAACGTTAA

Protein sequence :
MKTWLLALYDVLSRYKNVWNETWKIRKQLDSPVREKDENEFLPAHLELIETPVSNAPRFVSYSIMLFLTLAIIVSIFSNV
EIIATASGKFALSGRSKEIKPIENSLVKDIFVKEGEYVKKGELLLKLTALGAEADTLKTKTSLSQAKLEEFRYKSLLEAV
EKDQLPILDFSKIDLPFMTENDQKRVTLLIEEQFSTWQKQRHQKTLNLNKKEAEKLSYLARIKKYEGLINTEQVRLDDFR
ALYKEHAIAKHTVLDEENKYQDAINELEVYKASLMQVENEVLLAKEEQELVTQLFKNDILDKLKQATDNVNLLTFELDKN
NQRQQVSEIRAPVSGTVQQLKVHTIDGVVTTAETLMVVVPEEDSLEVTALIQNKDIGFVKEGQEVVIKVEAFPYTRYGYL
TGKVKNITLDAIEHPKLGLVFNTIIELDKKTLSAEEKEIPLSAGMEITAEIKTGMRSVISYLLSPLEESIDKSLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 2e-156 68
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 3e-156 68
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 4e-156 68
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 2e-141 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D7S_00602 YP_006286265.1 hemolysin D VFG1502 Protein 2e-156 68
D7S_00602 YP_006286265.1 hemolysin D VFG0908 Protein 8e-157 68
D7S_00602 YP_006286265.1 hemolysin D VFG1556 Protein 2e-156 68
D7S_00602 YP_006286265.1 hemolysin D VFG0843 Protein 5e-119 53