Gene Information

Name : ald1 (ACPL_1056)
Accession : YP_006264021.1
Strain : Actinoplanes sp. SE50/110
Genome accession: NC_017803
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 1090381 - 1091904 bp
Length : 1524 bp
Strand : -
Note : NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACCACGTATGTTCCGCCCGGCTCCGAAGGCGCGATCGTCAGCTACCAGTCCCGTTACGACCACTACATCGGCGGCGA
ATACGTTCCGCCGGCCAAGGGCCAGTACTTCGAGAATCCCACCCCGGTCACCGGGAGTGCGTTCACCGAGGTCGCCCGCG
GCACCGCCGACGACGTCGAGCGGGCCCTGGACGCCGCGCACGGCGCCGCCGACGCGTGGGGCCGCACCTCGGTCGCCGAA
CGCGCCACCATCCTCAACCGGATCGCCGACCGGATCGAGCAGAATCTGGAGAAGCTCGCCGTCGCCGAATCCTGGGAGAA
CGGCAAACCGGTCCGCGAGACGCTCGCCGCCGACCTGCCGCTCGCGGTCGACCACTTCCGCTACTTCGCCGGGGCGATCC
GCGCCCAGGAGGGCACCGCGGGCCAGATCGACGAGGACACCGTGGCGTACCACTTCCACGAGCCGCTCGGCGTGGTCGGT
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGGTCTGGAAGCTGGCGCCCGCGCTGGCCGCCGGCAACACCGTGGT
GCTCAAACCGGCCGAGCAGACCCCCGCCTCGATCCACTACCTGTTCTCGCTGATCGGCGACCTGCTCCCGGCCGGCGTGG
TGAACATCGTGAACGGCTTCGGCGTCGAGGCCGGCAAACCGCTGGCCAGCTCGAACCGGGTCGCCAAGGTGGCTTTCACC
GGGGAGACCACCACCGGGCGGCTGATCATGCAGTACGCCTCGGAGAACCTGATCCCGGTGACCCTGGAACTCGGTGGCAA
GAGCCCCAACATCTTCTTCGACGACGTGAGCGGCGCCGACGACGACTTCTTCGACAAGGCCCTCGAAGGCTTCGCGATGT
TCGCGCTCAACCAGGGCGAGGTGTGCACCTGCCCGAGCCGCGCGCTGATCCAGCAGGGTCACTACGCCGACTTCCTGTCC
GCGGGCGTCAAGCGGGTCGAGAACCTGCGGCAGGGCAACCCGCTGGACACCGACACGATGGTCGGCGCGCAGGCGTCCAA
CGACCAGTTCGAGAAGATCCTGTCGTACCTCGACATCGGCCGGAAAGAGGGCGCGAAGGCGCTGGTCGGCGGCGCGAAGG
CGGACCTCGGCGGCGACCTGTCCGGCGGCTTCTACATCCAGCCGACGATCTTCGAGGGCCGCAACGCGATGCGGATCTTC
CAGGAGGAGATCTTCGGGCCGGTGGTCTCGGTGACGCCGTTCGCCGACTTCGACGACGCGATCAAGATCGCCAATGACAC
GTTGTACGGGTTGGGAGCCGGCGTGTGGACCCGGGACATCAACCGGGCGTACCGGGCCGGTCGGGCGATCAAGGCCGGCC
GGGTCTGGACCAACTGCTACCACCTGTACCCGGCGCACGCCGCGTTCGGCGGATACAAGCAGTCCGGAATCGGCCGGGAG
AACCACAAGATGATGCTCGACCACTATCAGCAGACCAAGAATCTGCTCGTCAGCTACTCCCCCAAGGCCATGGGATTCTT
CTAG

Protein sequence :
MTTYVPPGSEGAIVSYQSRYDHYIGGEYVPPAKGQYFENPTPVTGSAFTEVARGTADDVERALDAAHGAADAWGRTSVAE
RATILNRIADRIEQNLEKLAVAESWENGKPVRETLAADLPLAVDHFRYFAGAIRAQEGTAGQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNTVVLKPAEQTPASIHYLFSLIGDLLPAGVVNIVNGFGVEAGKPLASSNRVAKVAFT
GETTTGRLIMQYASENLIPVTLELGGKSPNIFFDDVSGADDDFFDKALEGFAMFALNQGEVCTCPSRALIQQGHYADFLS
AGVKRVENLRQGNPLDTDTMVGAQASNDQFEKILSYLDIGRKEGAKALVGGAKADLGGDLSGGFYIQPTIFEGRNAMRIF
QEEIFGPVVSVTPFADFDDAIKIANDTLYGLGAGVWTRDINRAYRAGRAIKAGRVWTNCYHLYPAHAAFGGYKQSGIGRE
NHKMMLDHYQQTKNLLVSYSPKAMGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-141 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-147 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-147 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-147 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-146 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ald1 YP_006264021.1 aldehyde dehydrogenase VFG0082 Protein 1e-141 61