Gene Information

Name : metB (ACPL_964)
Accession : YP_006263929.1
Strain : Actinoplanes sp. SE50/110
Genome accession: NC_017803
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 957541 - 958692 bp
Length : 1152 bp
Strand : +
Note : Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGACTACCGATCACTATGGGTTCGACACCCTCGCCATCCACGCGGGGCAGGACCCGGATCCCCGCACCGGCGCGGTGGT
TCCGCCGATCTACCAGACCAGCACGTACGCGCAGGACGCGGTCGGCGCGCCGCGCCTCGGCTACGAGTACAGCCGTTCCG
GCAACCCGACCCGGGACGCCCTCCAGGAGTGCCTGGCCGCGATCGAGGGCGGCCGGCGCGGCCTGGCCTTCGCCAGCGGG
CTCGCCGCGGAGGACACCCTGCTGCGCGCGGTCTGCCGGCCCGGTGACCACGTCGTCATCCCGAACGACGCGTACGGCGG
CACGTACCGCCTGTTCTCCAAGGTCGCCGAGCGCTGGGGCCTGGACTGGACTGCCGTCCCGCTGGACGACTTCGACGCGG
TGCGGGCCGCCTTCCGTCCCGGGCACACCCGGCTGATCTGGGCCGAGACGCCGACCAACCCGCTGCTCAACATCGCCGAC
GTGACCACCCTGGCGACGCTGGCCCACGAGTACGACGCGATGCTCGCCGTGGACAACACCTTCGCCTCGCCGTACCTGCA
GCAGCCGCTCGCGCTCGGCGCCGACGTGGTGATCCACTCGACCACGAAGTACCTGGGCGGGCACTCCGACGTGGTCGGCG
GCGCGCTGGTGGTGGCCGACCCGGGGCTCGGCGACGAGCTGGCCTTCCACCAGAACGCGATGGGCGCGGTGAACGGCCCG
TTCGACGCCTGGCTGACGCTGCGGGGGATCAAGACCCTGGGTGTACGCATGGACCGGCACTGTGACAACGCCGAGCGGAT
CGTCGGGTTCCTCAGCGAGCACGAGAAGGTGGCGAGCGTGCTCTACCCGGGGCTGGAGAGCCACCCCGGCCACGAGACCG
CGGCCAAGCAGATGAGCCGGTTCGGCGGCATGGTGTCGTTCCGCGCGGCCGGCGGCCCGGAGCAGGCGGTGGAGATCTGC
AACCGGACGAAGCTGTTCGTGCTCGCCGAGTCGCTCGGCGGAGTCGAGTCGCTGATCGAGCACCCTGGGCAGATGACACA
TCTGTCGGCTGCGGGCTCAGCGCTTGAAGTTCCCGCCGATCTCGTGCGACTGTCTGTCGGCATCGAAACCGTTGACGATC
TGCTCGCCGACCTCGAGCAGGCGCTCGGCTAA

Protein sequence :
MTTDHYGFDTLAIHAGQDPDPRTGAVVPPIYQTSTYAQDAVGAPRLGYEYSRSGNPTRDALQECLAAIEGGRRGLAFASG
LAAEDTLLRAVCRPGDHVVIPNDAYGGTYRLFSKVAERWGLDWTAVPLDDFDAVRAAFRPGHTRLIWAETPTNPLLNIAD
VTTLATLAHEYDAMLAVDNTFASPYLQQPLALGADVVIHSTTKYLGGHSDVVGGALVVADPGLGDELAFHQNAMGAVNGP
FDAWLTLRGIKTLGVRMDRHCDNAERIVGFLSEHEKVASVLYPGLESHPGHETAAKQMSRFGGMVSFRAAGGPEQAVEIC
NRTKLFVLAESLGGVESLIEHPGQMTHLSAAGSALEVPADLVRLSVGIETVDDLLADLEQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-70 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-71 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_006263929.1 cystathionine gamma-synthase BAC0207 Protein 7e-63 44