Gene Information

Name : ACPL_8281 (ACPL_8281)
Accession : YP_006271227.1
Strain : Actinoplanes sp. SE50/110
Genome accession: NC_017803
Putative virulence/resistance : Virulence
Product : putative transcriptional regulator ycf27
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 9123893 - 9124597 bp
Length : 705 bp
Strand : +
Note : Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
GTGGAGACGATGACGGAGCGGCGGGTTCTGGTCGTCGAGGATGAGCGGGCCATCGCGGATGCGGTGGCCGCGCGGCTGCG
CGCCGAGGGGTTTCTGGTGCAGGTGGTCGGGGACGGGCCCAGCGCGGTGGAGGCGGCTCGGCGGGTCCCGCCGGATGTGG
TCGTGCTCGACGTGATGCTGCCCGGGTTCGACGGACTGGAGGTGTGCCGGCGGATCCAGGCCGAACGGCCGGTGCCGGTG
CTGATGCTGACCGCCCGTGGGGACGAGACCGACCTGCTCGTCGGGCTCGCGGTGGGGGCCGACGACTACATGGCCAAGCC
GTTCTCGATGCGCGAACTCGCCGCCCGGGTGCATGCGCTGCTCCGGCGGGTCGGCAAGACCGGAGCGGCCCGGGTGGCGG
CGCCGGCCGGGCCGCCGACGCTGCGGCTCGGGGACCTGGAGATCAACCAGGCGGAGCGGCGGGTGCTTCGCGGCGGGGCT
GAGGCGCATCTGACGCCGACCGAGTTCGACCTGCTCGTGCACCTCGCCCGGACCCCGCGGACGGTGCTGCCCCGGGAGCG
GCTGCTGGCCGAGGTCTGGGGCTGGGCGGACGCGTCCGGCACGCGGACCGTCGACAGCCACATCAAAGGCCTGCGCCGTA
AGCTGGGCGCCGACCTGATCCGCACCGTGCACGGGGTCGGCTACGCCCTGGACATCGAACGATGA

Protein sequence :
METMTERRVLVVEDERAIADAVAARLRAEGFLVQVVGDGPSAVEAARRVPPDVVVLDVMLPGFDGLEVCRRIQAERPVPV
LMLTARGDETDLLVGLAVGADDYMAKPFSMRELAARVHALLRRVGKTGAARVAAPAGPPTLRLGDLEINQAERRVLRGGA
EAHLTPTEFDLLVHLARTPRTVLPRERLLAEVWGWADASGTRTVDSHIKGLRRKLGADLIRTVHGVGYALDIER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 3e-22 42
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-21 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 AE000516.2.gene3505. Protein 3e-27 45
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_012469.1.7685629. Protein 5e-27 44
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 BAC0083 Protein 3e-23 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 AF155139.2.orf0.gene Protein 1e-24 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_002952.2859905.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_007793.3914279.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_002758.1121668.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_003923.1003749.p0 Protein 3e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_009641.5332272.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_013450.8614421.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_002951.3237708.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_007622.3794472.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_002745.1124361.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 NC_009782.5559369.p0 Protein 4e-26 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 CP001918.1.gene3444. Protein 7e-22 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 CP000647.1.gene2531. Protein 1e-21 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 VFG1390 Protein 5e-27 43
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 VFG1389 Protein 2e-22 42
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 VFG1702 Protein 1e-22 42
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 VFG0473 Protein 6e-23 41
ACPL_8281 YP_006271227.1 putative transcriptional regulator ycf27 VFG1563 Protein 9e-22 41