Gene Information

Name : ACPL_7909 (ACPL_7909)
Accession : YP_006270855.1
Strain : Actinoplanes sp. SE50/110
Genome accession: NC_017803
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 8718726 - 8720033 bp
Length : 1308 bp
Strand : +
Note : Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
GTGACCGACGTCTTCCACCACCGCCTGCGCAGCGCGGTCGAGGCGGCCCGGCCCTCGGTGTCCGGCCGGGTCACCGGGGC
GGTCGGCCTGCGGGTCACGGTCAGCGGACTCGAAGCCCGGGTCGGCGAGCTGCTGCGGATCGGCACCGGCCCGGACGCGG
TGCTGGCGGAGGTGGCGGCGCTGGACGGACAGCAGCTCAACTGCCTGCCACTGGGCCCGATCGCCGGGATCGGCGCCGGC
ACCCCGGCGGTCAGCACCGGCGGGCCGCTGCGCATCCCGGTCGGCCCCGACCTGCGCGGGCGCATCCTGGACGGGCTCGG
CCGCCCGATGGACGGCGGGCCACCGCTGCGCGGCGAACTGGTGGGCATCGAGCAGGCCCCGCCCTCGGCGATGGAACGGC
AGCTCGTCGACAGGCCGATGTCGCTGGGCGTGCGGGTCCTGGACACGCTCGTCCCGTGCGGCCGCGGCCAGCGGATCGGC
ATCTTCGCCGGCTCCGGGGTCGGCAAGTCGACGCTGATGAGCATGATCACCCGGGGCACCTCGGCCGAACTCAACGTGGT
CGCGCTGGTCGGTGAGCGCGGCCGTGAGGTCCGCGAGTTCATCGAGCACGACCTCGGGCCGGAGGGCCTGGCCCGCTCGG
TGGTGGTGATCGCCACCTCGGACACCCCGCCGCTGGTCCGGTTGCGGGCCGGCTCGGTGGCCACCCGGATCGCCGAGTAC
TACCGCGACGAGGGCGCCGATGTGCTGCTGATGATGGACAGCGTGACCCGCGCCGCGATGGCCCAGCGCGAGGTCGGCCT
CTCGGTCGGCGAGCCGCCGGCCACCCGGGGCTACCCCCCGTCGGTCTTCGCCATGCTGGCCAGCCTCCTGGAACGCGCCG
GGCCGGGGGCCCGGGGCAGTATCACCGGCCTGTACACGGTGCTGGTCGAGGGCGACGACCACAACGAGCCGATCGCCGAC
GCGGCCCGCTCGATCCTGGACGGCCACATCGTGCTGGACCGCAAACTGGCCACCGCCGGGCATTTCCCGAGCATCCAGGC
GCTCGACTCGATCTCCCGCGTCGCCAACAAGATCACGACGCGGGAGCAGCGCGCCGACGCCACCGAACTCCGCCGGCTGA
TGGCCGCCCACCGCGACGTCCGCGAGCTGGTGGAGATCGGCGCCTATGTGCCGGGGACCAACCCGGAGGCCGACCGGGCC
AACGCGGCCTGGCCCCGGATCAGCGCGTTCCTGCGCCAGGACATCGACGAGCGCATCACCGCCGACGACGCCTGGGCCGC
CTTGCGCGCCCTTCTGGCGACGACTTAG

Protein sequence :
MTDVFHHRLRSAVEAARPSVSGRVTGAVGLRVTVSGLEARVGELLRIGTGPDAVLAEVAALDGQQLNCLPLGPIAGIGAG
TPAVSTGGPLRIPVGPDLRGRILDGLGRPMDGGPPLRGELVGIEQAPPSAMERQLVDRPMSLGVRVLDTLVPCGRGQRIG
IFAGSGVGKSTLMSMITRGTSAELNVVALVGERGREVREFIEHDLGPEGLARSVVVIATSDTPPLVRLRAGSVATRIAEY
YRDEGADVLLMMDSVTRAAMAQREVGLSVGEPPATRGYPPSVFAMLASLLERAGPGARGSITGLYTVLVEGDDHNEPIAD
AARSILDGHIVLDRKLATAGHFPSIQALDSISRVANKITTREQRADATELRRLMAAHRDVRELVEIGAYVPGTNPEADRA
NAAWPRISAFLRQDIDERITADDAWAALRALLATT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-85 56
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 55
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 55
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-81 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-81 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-81 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-81 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-81 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-81 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 53
lscN AAO18044.1 LscN Virulence TTSS locus Protein 7e-85 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-77 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-77 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-77 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-77 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-77 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-79 51
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-79 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-79 51
escN AAC38383.1 EscN Virulence LEE Protein 4e-79 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-79 51
escN AAC31513.1 L0034 Virulence LEE Protein 3e-79 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-79 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-79 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-79 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-78 51
escN AAK26715.1 EscN Virulence LEE Protein 8e-79 50
escN AAL57542.1 EscN Virulence LEE Protein 8e-79 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-79 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-79 49
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-66 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-61 46
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-78 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-57 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-57 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-64 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-63 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-63 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-63 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-63 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-68 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-61 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-63 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-63 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-64 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-64 42
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-62 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-62 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0048 Protein 3e-88 55
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0192 Protein 1e-92 54
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0390 Protein 4e-89 52
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0515 Protein 3e-77 51
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0812 Protein 2e-79 51
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0730 Protein 2e-79 51
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG2331 Protein 1e-82 50
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG1254 Protein 4e-85 49
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG2144 Protein 4e-79 46
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG2459 Protein 1e-64 45
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG1778 Protein 1e-67 45
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG0555 Protein 2e-63 44
ACPL_7909 YP_006270855.1 flagellum-specific ATP synthase VFG1008 Protein 7e-64 44