Gene Information

Name : ACPL_6691 (ACPL_6691)
Accession : YP_006269641.1
Strain : Actinoplanes sp. SE50/110
Genome accession: NC_017803
Putative virulence/resistance : Virulence
Product : Alkaline phosphatase synthesis transcriptional regulatory protein sphR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7347432 - 7348124 bp
Length : 693 bp
Strand : -
Note : Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
GTGGCGGTGAGCGATGCGTCGAAGGGGCTCGTCCTGGTCGTCGAGGATGAGCGGCCGATCGCCGACCTGGTCCGGCTCTA
TCTGAGCCGGGAGGGATTCGGGGTGCAGGTCGAGCACGACGGCGCCGCGGGGCTGGCGGCGGCGCGGCGGCTGCGGCCGG
TGGCGTGCATCCTGGACATCGCGCTGCCCGGGATGGACGGGACGGAGATCTGCCGCCGACTGCGCGCCGACGGCGACTGG
ACGCCGGTGATCTTCCTGACCGCGCGGGACGACGAGGTCGACCGGATCCTCGGCCTTGAGCTGGGTGGGGACGACTACGT
CACCAAGCCGTTCAGCCCGCGTGAGCTGGTCACCCGGGTCAAGGCGCTGCTGCGGCGGGCCGCCGGGCCGCCGGAGGAGG
ACGGCGTGCGCCGACTGGGCCCGGTCGCGCTCGACCGGAGCCGCCGCGCGGCCACCGTGGACGGGCAGGCGGTGACGCTG
ACCGCGACCGAGTTTGATCTGCTCGCGCACCTGCTCGGCCGGCCCGGGCGGGTGTTCACCCGGGAGGAGCTGCTGGCCGC
GGTCTGGGGCTACGCCTCGCACGCCGGCACCCGCACGGTGGACGTGCACGTGGCCCAGGTCCGGGCCAAGCTCGGCGGCG
CGGCCGGCCTGATCCGCACGGTCCGCGGCGTGGGCTACACCGCCGATGCGTGA

Protein sequence : 
MAVSDASKGLVLVVEDERPIADLVRLYLSREGFGVQVEHDGAAGLAAARRLRPVACILDIALPGMDGTEICRRLRADGDW
TPVIFLTARDDEVDRILGLELGGDDYVTKPFSPRELVTRVKALLRRAAGPPEEDGVRRLGPVALDRSRRAATVDGQAVTL
TATEFDLLAHLLGRPGRVFTREELLAAVWGYASHAGTRTVDVHVAQVRAKLGGAAGLIRTVRGVGYTADA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 1e-20 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR AE000516.2.gene3505. Protein 7e-35 45
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_012469.1.7686381. Protein 2e-39 44
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR BAC0197 Protein 3e-29 44
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_003923.1003749.p0 Protein 1e-42 43
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_002952.2859905.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_007793.3914279.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_002745.1124361.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_009782.5559369.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_002951.3237708.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_007622.3794472.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_002758.1121668.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_009641.5332272.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_013450.8614421.p0 Protein 1e-42 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR BAC0083 Protein 2e-29 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR BAC0638 Protein 9e-23 42
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR NC_012469.1.7685629. Protein 5e-37 41
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR AE016830.1.gene1681. Protein 5e-36 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR VFG1386 Protein 9e-33 45
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR VFG1389 Protein 3e-29 45
ACPL_6691 YP_006269641.1 Alkaline phosphatase synthesis transcriptional regulatory protein sphR VFG0473 Protein 2e-24 41