Gene Information

Name : pykF (SMULJ23_0855)
Accession : YP_006251132.1
Strain : Streptococcus mutans LJ23
Genome accession: NC_017768
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 906633 - 908135 bp
Length : 1503 bp
Strand : +
Note : similar to gi|24379618, percent identity 100 in 500 aa, BLASTP E(): 0

DNA sequence :
ATGAATAAACGCGTAAAAATTGTTGCAACTTTAGGTCCAGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
CTATTGGGGTGAAAAGCTTGATGTTGAAGCTTCAGCAGCAAAAATTGCTGAATTGATTACAGAAGGAGCCAATGTTTTTC
GTTTTAACTTTTCACATGGTGACCATGCTGAGCAAGGTGAACGTATGGCGACCGTACGTCGCGCGGAAGAATTGGCACGT
CAAAAGGTTGGATTCCTTCTTGATACTAAAGGACCTGAAATGCGTACGGAATTGTTTGCAGATGGTGTCAAAGAATATGA
ATATAAGACTGGTGATAAACTTCGTATAGCAACTAAACAAGGTATTGAATCAACTAAGGATGTCATTGCTTTAAATGTTG
CAGGCGGTCTTGATATTTATGATGATGTTGCTGTCGGTCAGACTATTCTTATTGATGATGGGAAACTTGGCCTTACAGTA
ACTGCTAAAGATATTACGACTCGCGAGTTTGAAGTAACCGTTGAAAATGATGGTATTATTGCTAAACAAAAAGGTGTCAA
TATTCCTAATACTAAAATTCCTTTCCCAGCACTTGCTGAGCGTGATAATGCAGATATTCGCTTTGGTTTGGAACAAGGTC
TTAACTTTATTGCTATTTCTTTTGTTCGTACTGCTAAGGATGTTAATGAAGTTCGTCAAATTTGTAAAGAAACAGGTAAC
GAGCACGTAAAACTTTTTGCTAAAATTGAAAATCAACAAGGTATTGATAACATTGATGAAATCATTGATGCAGCTGACGG
TATCATGATTGCTCGCGGTGACATGGGTATTGAAGTGCCGTTTGAAATGGTTCCAGTTTATCAAAAAATGATTATCACGA
AAGTTAATGCAGCAGGGAAGTCAGCTATCACAGCAACAAATATGCTTGAAACAATGACTGACAAACCACGTGCAACACGT
TCTGAAGTCTCTGATGTCTTTAATGCTGTCATTGATGGTACTGATGCAACAATGCTTTCTGGTGAATCAGCTAATGGTAA
GTATCCAGTTGAAGCTGTTCGTACCATGGCAACAATTGATAAGAATGCTCAAACACTTCTTAATGAATATGGCCGTTTGA
ATTCAGATAATTTGCCACGTACCAACAAGACTGAAGTTGTCGCTTCAGCTGTTAAAGATGCGACTAAATCAATGGATATT
AAATTGGTTGTTACAATTACAGAATCTGGTAACACAGCTCGTTTAATTTCAAAATACCGTCCGGATGCAGATATCTTAGC
TTTAACATTTGATGAAAAAGTCCAAAAATCATTGATGATTAACTGGGGAGTTATTCCAATCTTAACAGAAAAACCTGCAT
CTACTGATGATATGTTTGAAATTGCAGAAAAAGCAGCTCTTAAATCAGGTTTGGTAGAGTCTGGTGACAACATCGTTATT
GTTGCTGGTGTACCGGTTGGATCTGGTGGTACTAATACTATGCGTGTTCGTACCGTTCAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAAKIAELITEGANVFRFNFSHGDHAEQGERMATVRRAEELAR
QKVGFLLDTKGPEMRTELFADGVKEYEYKTGDKLRIATKQGIESTKDVIALNVAGGLDIYDDVAVGQTILIDDGKLGLTV
TAKDITTREFEVTVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVNEVRQICKETGN
EHVKLFAKIENQQGIDNIDEIIDAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKSAITATNMLETMTDKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLNSDNLPRTNKTEVVASAVKDATKSMDI
KLVVTITESGNTARLISKYRPDADILALTFDEKVQKSLMINWGVIPILTEKPASTDDMFEIAEKAALKSGLVESGDNIVI
VAGVPVGSGGTNTMRVRTVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-69 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-70 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_006251132.1 pyruvate kinase VFG0479 Protein 1e-70 43