Gene Information

Name : SAEMRSA15_00470 (SAEMRSA15_00470)
Accession : YP_006236424.1
Strain : Staphylococcus aureus HO 5096 0412
Genome accession: NC_017763
Putative virulence/resistance : Unknown
Product : type I restriction-modification system endonuclease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 61051 - 64185 bp
Length : 3135 bp
Strand : +
Note : -

DNA sequence :
ATGAAGATGATCTTTCAATTTAGTGAAGATGATTTAGAACAGGTTGCACTGAAGTGGTTTGAGGGTCTTGGCTATTCTGT
TAAGAATGGTCGAGATAGTAGTGACAATGGGATTATGAATGAACGGGAGAGCGACAAAGATGTTGTGCTTGATGATCGTT
TGGAAGCAGCTTTGAGACGCATTAATCCTGAACTAAACAATAGTGCAATTGAACAGGCAATTCATGAAATTTCTATTGAG
AAGTCTCCTAGTTTATTAGAGAATAATCGTTCTTTCCATGAAATGATTACTAATGGTATCGAGGTTGAACACTATAATGA
TGATGGTGAGACGATTAATGATTTGGTCTATGTGCTTGACTTTGATAACCCAGGAAATAATGATTTCTTAGCGGTTAATC
AATTAACTGTTGTAAATGGAGATTATAAAAAAAGACCTGATATTGTGTTATTCATAAATGGATTACCAGTAGTGGTAATT
GAACTGAAAAATTCTACAAATGAATCTGTTGGTATTGAAGACGGGTATCATCAGTTAGAAACTTATAAAATGAGAATTCC
ACAATTATTTAATCATAATGCAGTATTAGTAACGAGTGATGGTGTCAATACAAAAGCTGGTTCTTTAACTGCTGATTATG
ACCGTTTTATGACTTGGCGTACTAAAGATGGAAAAACTGAAGATTCATCAACGTTTCGTAGTTTAGATATATTGATTCAC
GGTATGTTAAATAAAGAGGTACTATTAGATTTAATTCGTCATTTTGTTTTGTTCCAAGATGATGGTAAAGGAAATATAGT
TAAAATATTAGCTGCATATCATCAATATTATGCGGTTAATAAAGCTGTTGATCGTGCTATGGAAGCAACATCTGAACATG
GTGATGGTAAGGGCGGCGTTATTTGGCACACACAAGGTTCTGGTAAGAGTTTGACAATGGTCTTCTTCTCAGGAAAGTTA
ATTCAAAAATTAAATAATCCAACATTAGTGGTCGTAACAGACCGTAATGACTTAGACAATCAATTATATGGTACTTTTGT
TAAGTCCAAAGGACGCTCAGGTAAAGGATTACTAAGACAAACACCTAAACAAGCAGAATCACGAAAAGAATTGAAAGAAC
TATTATCTGTAGAATCAGGTGGTATTGTATTTACAACTATGCAGAAATTCGAACCTGAAGAAGGTCAAGTGACAATGGAT
GCTTTAACAGAACGTAAAAATGTAGTAGTTATGGCAGACGAAGCACACCGCACACAATATGGTTTTAAAGCAACTTACAA
TGAAAAAGGTGAAGGTATAAAATATGGTTATGCAAAATATTTAAGAGACGCTTTACCTAACGCTTCGTTCGTTGGTTTTA
CTGGAACACCTGTATCTTCGACAGATAAGAATACGCAAATGGTATTTGGTAATTATATTGATGTATATGATATGACACAG
TCTGTAGAAGACGGTAGTACGGTTAAAATATACTATGAAAGTCGTATTATTCCATTAAATTTACCAACTGATTTAGATAT
TGATGATGCATATGATGTCATTACTTTTGGCCAAGAAGAAGATACTAAATCTCGATTGAAATCTAAATGGTCACGTATAG
AAGCTCTATCTGGTGCAGAAAAACGAGTACATGCTTTAGCGACTGAAATTATTAATCACTTTGAAACAAGACAGAAGGCA
ATGAACGGTAAAGGTATGATTGTCACAATGAGTCGTCGTATTGCAGTTGATTTATATGATGAAATTATAAGACTTAAACC
TGAATGGCATTCTGATGATGACGACAAAGGTGTAATTAAAGTCGTTATGACAGGTTCATCAAGTGATCCGCAAAACTTCC
AAAAACATATAGGTCCGAAAAAGAGAAGAAACCTTTTAGAGAATCGTATGAAAGATATTAATGATGAACTGCAACTCGTA
ATTGTGCGAGACATGTGGTTAACAGGATTTGATGTACCTTCAATGCATACAATGTACATAGATAAACCGATGAAAGGTCA
TAATTTAATGCAAGCTATTGCACGTGTTAATAGAGTATTTAAAGATAAACCAGGTGGCTTAATTGTTGACTATGTAGGTA
TTGCTGAAAGCCTGAAGGAAGCACTAAAAGAGTATACGGACTCTGATAGAGAACAAACAGGTATAGATACAGATAAAGCG
CTAGAACTAATGTTAGTGAAATACGATATCATTCAAGATATGCTATATAACCATGACTATTCTGACTTTGAGTCAGAAGA
TCAATTAAATCGCTATAATGCTATCTCAAATACGATGGATTATATCATTGGATTAGGTGAGAAAGAAAGAGAGCGATTTG
TGACAACAGTTACAGAACTTTCTAAGGCTTTTGCATTATGTGCAACAGAGGAAGCTGCTCAAGAACTAAATAGTGAAATT
GCGTTTTTAAAAGCAGTAAAATCAGGACTTGTTAAATTATTAGCTCCACCTAATGAAGGAAGCAAGCTTAAAAAGACACC
TGCTGAAATAGAAGCAGAAATAAATCAATTGATTTCAAAGTCAGTTGTAACTGAAGAAGTTGTAGATATTTATCAAACAC
TCGGAATTGAAAATCCAGATATCTCAATATTGTCGGATGATTTCTTAAAAGATGTAGAAGGACTACAGCAAAAAAATGTT
GCAGTTGAATTGTTGAACAAATTACTCAAAGGACAAGTTAAGTCATTAATGAAAACTAATACTACTGTATCTAAAAGGTT
TTCTGAGATGCTAAGTAAATCAATACAAAAATATAATAACCGTTCTATCGAAGCATCAAAAGTCATAGAAGAATTAATTC
AAATGGCGAAAGAAATAAATCAAGAAAAAGAAAGAGGAAAAGAATTAGGTTTAAGTACTGAAGAAATTGCATTTTATGAC
GCATTAGCTTCACATGAAACAGCAAAAGAAGCGATGGATGATAAAGAATTAAGGGCTATTGCACATGAATTAACAAAAAC
GGTTAAGAATAATATGAGCGTAGACTGGTCAAAACGTGAGAGCGCAAAGGCTAAAATGAGAGTCCAAGTAAGACGACTAT
TAAAGAAATATGGTTATCCACCAGACATACAAAAAATGGCAGTAGAACAAGTAGTGGAACAAGCAGAATTAATGGCAAGT
CAACAATATAAATAA

Protein sequence :
MKMIFQFSEDDLEQVALKWFEGLGYSVKNGRDSSDNGIMNERESDKDVVLDDRLEAALRRINPELNNSAIEQAIHEISIE
KSPSLLENNRSFHEMITNGIEVEHYNDDGETINDLVYVLDFDNPGNNDFLAVNQLTVVNGDYKKRPDIVLFINGLPVVVI
ELKNSTNESVGIEDGYHQLETYKMRIPQLFNHNAVLVTSDGVNTKAGSLTADYDRFMTWRTKDGKTEDSSTFRSLDILIH
GMLNKEVLLDLIRHFVLFQDDGKGNIVKILAAYHQYYAVNKAVDRAMEATSEHGDGKGGVIWHTQGSGKSLTMVFFSGKL
IQKLNNPTLVVVTDRNDLDNQLYGTFVKSKGRSGKGLLRQTPKQAESRKELKELLSVESGGIVFTTMQKFEPEEGQVTMD
ALTERKNVVVMADEAHRTQYGFKATYNEKGEGIKYGYAKYLRDALPNASFVGFTGTPVSSTDKNTQMVFGNYIDVYDMTQ
SVEDGSTVKIYYESRIIPLNLPTDLDIDDAYDVITFGQEEDTKSRLKSKWSRIEALSGAEKRVHALATEIINHFETRQKA
MNGKGMIVTMSRRIAVDLYDEIIRLKPEWHSDDDDKGVIKVVMTGSSSDPQNFQKHIGPKKRRNLLENRMKDINDELQLV
IVRDMWLTGFDVPSMHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLIVDYVGIAESLKEALKEYTDSDREQTGIDTDKA
LELMLVKYDIIQDMLYNHDYSDFESEDQLNRYNAISNTMDYIIGLGEKERERFVTTVTELSKAFALCATEEAAQELNSEI
AFLKAVKSGLVKLLAPPNEGSKLKKTPAEIEAEINQLISKSVVTEEVVDIYQTLGIENPDISILSDDFLKDVEGLQQKNV
AVELLNKLLKGQVKSLMKTNTTVSKRFSEMLSKSIQKYNNRSIEASKVIEELIQMAKEINQEKERGKELGLSTEEIAFYD
ALASHETAKEAMDDKELRAIAHELTKTVKNNMSVDWSKRESAKAKMRVQVRRLLKKYGYPPDIQKMAVEQVVEQAELMAS
QQYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 82
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 81
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 81
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 46