Gene Information

Name : guaA (HPPC18_05160)
Accession : YP_006229257.1
Strain : Helicobacter pylori PeCan18
Genome accession: NC_017742
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1088393 - 1089919 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACGCAGCTGATCGCTAGAAGATTGAGAGAGAGCGGGATTTATGCAGA
GATAGTCCCTTTTTTTGAAAGCGTAGAAAACATTCAAAAAAAAGCCCCTAAGGGCTTGATTTTGAGTGGGGGACCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAATGAAAAAATCTTTGATTTGAATTTACCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGCCTATGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CGCTCAAAATTCTGTGATTTTTGAAGGCGTAAAGATTAAAAGCCTTGTGTGGATGAGCCACATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCGCCCTATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTTGTTCAAAGCGAAGAAGGAGGCAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATTACGAGGCTGAAAGAACAAATTGCTAACGCTAAGGTGTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTACACAGAGCCATTGAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAAAGTCCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAGTCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AGACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAAAAACACCATTTAAAAGGCAAAATTGAGTTTTTAGCTCAAGGCACT
CTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACACACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTGCGCTTGTTGGGTAAAGAAT
TGGGCGTTAGTCAGGATTTTTTAATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCGATAAGGATTTTAGGCGAAATCAGT
GAGAGTAAGATCAAACGCTTGCAAGAAGCGGATGCTATTTTTATAGAGGAGCTTAAGAAAGCCCGTTTATACGATAAGGT
TTGGCAAGCCTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTGATGGGGGATAATCGCACTTATGAAAACGCTATTT
GTTTAAGAGCGGTGAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTGGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCGCCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESVENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLNLPILGICYG
MQYLVDFFGGVVAYANEQEFGKAVLEIAQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPYCAIENGKIFGL
QFHPEVVQSEEGGKILENFALLVCGCEKTWGMQHFAQREITRLKEQIANAKVLCAVSGGVDSTVVATLLHRAIEDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEVFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAIRILGEIS
ESKIKRLQEADAIFIEELKKARLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-135 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-135 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-135 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-115 48