Gene Information

Name : ureB (HPPC18_00360)
Accession : YP_006228366.1
Strain : Helicobacter pylori PeCan18
Genome accession: NC_017742
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 73922 - 75631 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGCTTCTATGTATGGCCCTACTACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACTTTAAGAGAAG
GCATGAGCCAATCCAACAACCCCAGCAAAGAAGAACTGGATTTAATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGCAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCTGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCATTTCATCTCCCCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACGATGATTGGTGGCGGA
ACTGGCCCTGCTGATGGCACTAACGCAACCACTATCACTCCAGGCAGAAGAAATTTAAAATTTATGCTCAGAGCGGCTGA
AGAATATTCCATGAACTTTGGTTTCTTGGCTAAAGGTAACGTTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGTTTTAAAATCCACGAAGACTGGGGAACAACTCCTTCTGCAATCAACCATGCGTTAGATGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCAGCCATTGCCGG
ACGCACTATGCACACTTTCCACACTGAAGGCGCTGGTGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTGCCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCAGAACACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACTAGTTCTGACTCTCAAGCTATGGGTCGTGTGGGTGAAGTTATCA
CCAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCCGCATTCTTTGGCGTAAAACCCAACATGATCATCAAAGGCGGGT
TCATTGCGTTAAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACTCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCAAACATCACTTTTGTATCCCAAGCGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKFMLRAAEEYSMNFGFLAKGNVSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 7e-159 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 7e-159 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-146 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-146 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-146 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 9e-146 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006228366.1 urease subunit beta VFG0270 Protein 0.0 99