Gene Information

Name : HPPC18_00550 (HPPC18_00550)
Accession : YP_006228398.1
Strain : Helicobacter pylori PeCan18
Genome accession: NC_017742
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 111475 - 112617 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAGCTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGCTTAGCCGGGATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTAGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTTAATAA
AGTGCTTGTCAAAAACGGGCTTTCATGCACCATTATAGACACTAGCGATATATCCCAAATTAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAGACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTCGCT
AAAGATCATAATTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
TGTTGTGGTGCATAGCGGCACAAAATACTTAGGCGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACCAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTTCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTGGGATTGCGCATGGAGGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAATTTTTAGAAAAACACCC
TAAAGTGGAAAGGGTTTATTACCCAGGCCTACCCACCCACCCTAATTACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACCCTCAAAAATGACAGCGAGGCGGCTCTTTTTGTAGAAAGTCTTAAGTTATTCATTTTAGGC
GAGAGTTTGGGTGGGGTGGAAAGCTTGGTAGGGATTCCAGCGCTAATGACCCATGCGTGTATCCCTAAAGCGCAACGAGA
AGCCGCAGGGATCAGAGATGGCTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATCTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAAGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHNLLTIVDNTFATPYCQNPLLLGADVVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKAQMRGFSGMLSFTLKNDSEAALFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-97 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-98 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-71 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPPC18_00550 YP_006228398.1 cystathionine gamma-synthase BAC0207 Protein 2e-62 44